Calcium glycerophosphate – medicine, used as a regulator of calcium-phosphorus metabolism in the body.
Calcium Glycerophosphate is produced in the form of white flat-cylindrical tablets with a chamfer, in contour cellless packages of 10 pcs.
One tablet contains 200 mg of calcium glycerophosphate and such excipients, How:
Calcium glycerophosphate is prescribed for a decrease in the overall resistance of the body, malnutrition, hypocalcemia, fatigue and exhaustion nervous system.
The drug is also used as a general tonic in cases of rickets.
The use of calcium glycerophosphate is contraindicated in case of hypersensitivity to the components included in the product, as well as in cases of:
The tablets are taken orally after meals. The dosage for adults is 1-2 tablets twice or thrice a day; children (including newborns) are prescribed 1 tablet. 1-3 times a day.
It is recommended to crush calcium glycerophosphate tablets and dissolve them in a small amount of water when using the product for children under 1 year of age. The duration of therapy varies between 14-28 days, with possible repetition of the course as prescribed by the doctor.
The instructions for calcium glycerophosphate indicate that the drug can cause hypercalciuria, hypercalcemia, nausea, diarrhea, abdominal pain and constipation.
In case of an overdose of the drug, an increase in the above side effects is observed. In such cases, it is recommended to stop taking the drug and prescribe calcitonin.
With simultaneous use, calcium glycerophosphate can increase the absorption of tetracyclines, potentiate the toxic and therapeutic effects of cardiac glycosides, as well as:
It should be taken into account that glucocorticosteroids reduce the absorption of calcium, and loop diuretics increase the excretion of the trace element by the kidneys.
Foods such as rhubarb, spinach, grains and bran can reduce the absorption of calcium from the gastrointestinal tract.
When using the drug during breastfeeding It should be taken into account that calcium is released with breast milk. In this regard, it is important to avoid the use of calcium glycerophosphate in cases where infant Vitamin D3 or calcium supplements are prescribed.
A synonym for the drug is Glycerophosphate granules. Analogs of calcium glycerophosphate include Calcium gluconate, Additive calcium, Calcium-Sandoz forte and Hydroxyapatite paste.
In accordance with the instructions, calcium glycerophosphate should be stored in a place protected from light, dry and out of reach of children, at room temperature.
Calcium glycerophosphate is a means of regulating calcium-phosphorus metabolism. It has a general strengthening and tonic effect, and also affects stimulation metabolic processes body.
This remedy helps increase protein production and is a source of calcium and phosphorus. Thanks to its intake, the functions of the nervous system are noticeably improved, the body’s metabolic process is stimulated, as well as strengthening bone tissue accelerates.
Pharmacodynamics
The product speeds up anabolic processes and replenishes calcium deficiency. Calcium ions are involved in the transmission of nerve impulses, playing an important role in the process:
The drug normalizes metabolic process calcium and phosphorus in the body and has a general strengthening effect.
Pharmacokinetics
Calcium is absorbed in the gastrointestinal tract in the form of ions that are distributed in the tissues. Half total calcium, found in the blood serum, are calcium ions, 45 percent are directly bound to protein, and only 5 percent are part of anion complexes. Most of the calcium, namely 4/5, is excreted through the intestines, the rest - 1/5, is excreted in the urine.
The product is released in the form of tablets, which are sold in contour packaging without cells. Quantity of 10 or 20 pieces.
Price
Calcium glycerophosphate, tablets can be bought at the pharmacy. On average the price for this product starts from 85 rubles.
Storage conditions and periods
This drug is available without a prescription and is valid for 5 years.. Storage conditions are also simple - keep in a cool place or at room temperature, dry and protected from sunlight.
Taking the drug together with other calcium supplements can cause:
GCS influences the reduction in calcium absorption. Hypercalcemia may result from the simultaneous use of calcium-containing drugs or thiazide diuretics. Loop diuretics increase calcium excretion through the kidneys.
Taking calcium glycerophosphate is prohibited:
There is no need to use the drug if:
OverdoseSymptoms of overdose manifest themselves in allergic reactions. For treatment, it is necessary to discontinue use of the drug. The antidote is calcitonin, administered intravenously from 5 to 10 IU per day per 1 kg of total body weight.
In general, the drug is well tolerated if its dosage has not been changed, but in some situations allergic reactions caused by increased level sensitivity or individual intolerance to the components of calcium glycerophosphate.
When the drug is taken for a long time in large quantities, side effect will appear as:
When such negative reactions the drug is stopped and symptomatic treatment. Calcitonin is an antidote and is administered at a dose of 5 IU per day per 1 kg of total body weight.
Calcium glycerophosphate for children is given starting from 3 years old due to the form of its release. If there are indications, the doctor may prescribe the remedy for children under three years of age. In this case, the tablet is crushed and dissolved in water in an amount of one teaspoon.
When undergoing a course of treatment with medications containing calcium, experts recommend taking products with iron. At this stage, it is necessary to bring the diet back to normal, namely, to exclude from it:
During long-term treatment drug, when taken cardiac glycoside or a diuretic, you need to monitor the level of creatinine and calcium in the blood.
If the indicators are elevated, then the drug is stopped for a while or the calcium dosage is reduced. The absorption of the element that enters the gastrointestinal tract is enhanced by vitamin D3, so taking into account the presence of these two components from food and other sources will help prevent an overdose.
When is the drug prescribed? pregnant woman, who takes vitamins, you need to contact a specialist. The use of the drug during breastfeeding should be discontinued if the child receives calcium and vitamin D3 from other drugs, since calcium tends to quickly penetrate into breast milk.
Calcium glycerophosphate in bodybuilding. The value of the drug for bodybuilders is its ability to accelerate protein absorption and improve the metabolic process. It helps increase appetite. When taking it, you need to limit the amount of fats that are replaced with proteins. It is recommended to take the product in courses. The reviews are positive.
Additive E 383 combines two vital necessary element: calcium and phosphorus. It would seem that an antioxidant should be present in many products. For a long time so it was. But then the food industry was banned from using the synthetic substance.
Let's look at the reasons for this decision.
Calcium glycerophosphate is the name of the product, enshrined in official documents of the Ministry of Health of the Russian Federation and the State Committee for Sanitary and Epidemiological Supervision.
International name- Calcium glycerophosphate.
In the European codification, the substance is registered under the index E 383 (E-383).
You can find synonyms:
Calcium glycerophosphate is included in the category. Until 2010, in food production it performed the technological function of a thickener and consistency.
Nicotinic acid has nothing to do with a dangerous alkaloid. Detailed information You will find information about this dietary supplement in.
Calcium glycerophosphate as a medicinal and vitamin preparation They are produced by many domestic enterprises (Veropharm, Kaustik, Uralbiopharm and others). All of them use foreign raw materials.
As an intermediate chemical ingredient, food additive E 383 is supplied by: 
Calcium glycerophosphate is a synthetic substance. Like any product of modern chemistry, it can be equally beneficial and harmful.
It's safer to replenish your body's calcium stores daily use his natural sources: cottage cheese, milk, nuts, cereals.
Instructions for use describe in what cases and for what these tablets can be used. Since these tablets belong to the pharmacotherapeutic group “calcium-phosphorus metabolism regulator,” they also have a tonic and restorative pharmacological effect, regulate the exchange of calcium and phosphorus and stimulate metabolic processes. The medicine is indicated for a lack of calcium in the body, for rickets. It is also recommended if there are signs physical fatigue and nervous exhaustion in humans.
There are also contraindications. Although they are few, they exist. This drug should not be prescribed to small children under the age of two years, with an excess of calcium, if thrombosis, thrombophlebitis and atherosclerosis have been diagnosed. Side effect only one is indicated - this allergic reaction, which doesn't happen very often. The drug is available in the form of 200 mg tablets, 10 or 20 tablets per package. It is acceptable to take the medication during pregnancy and lactation.
The regimen for taking this type of calcium is extremely simple: it is taken before meals, 1 tablet three times a day. For children over two years of age, the dosage is from a quarter to whole tablet twice or thrice a day. For children better than a pill crush before use. There are also special instructions during treatment. It is recommended to exclude vinegar and sorrel from the diet and add iron supplements.
It is not recommended to combine calcium supplements with potassium supplements due to possible overdose calcium. If calcium and glucocorticosteroids are taken at the same time, calcium absorption deteriorates. When used simultaneously with cardiac glycosides, their toxic effects on the body may increase, and when used together with tetracyclines, their absorption may increase.
medicine
Calcium glycerophosphate
Trade name
Calcium glycerophosphate
International nonproprietary name
Dosage form
Pills
Compound
One tablet contains
active substance - calcium glycerophosphate 0.2 g;
excipients - potato starch, calcium stearate, talc
Description
Flat-cylindrical tablets, white, with chamfer
Pharmacotherapeutic group
Mineral supplements. Calcium preparations
ATX code A12AA
Pharmacological properties
Pharmacokinetics
Calcium is absorbed in ionized form in the gastrointestinal tract and distributed in tissues. 50% of total serum calcium is represented ionized calcium, 5% is part of anionic complexes, 45% is associated with proteins in blood plasma. About 20% of calcium is excreted in the urine, 80% through the intestines.
Pharmacodynamics
A remedy that replenishes calcium deficiency. Calcium ions take part in the transmission nerve impulses, contraction of smooth and striated muscles, myocardial functioning, blood coagulation; necessary for the formation of bone tissue, maintaining electrolyte balance and the functioning of other systems and organs. Normalizes the exchange of calcium and phosphorus in the body, has a general strengthening effect.
Indications for use
Hypocalcemia
Reduced general resistance, fatigue and nervous exhaustion
Hypotrophy
Directions for use and doses
Prescribed orally after meals for adults: 1-2 tablets (0.2-0.4 g) 2-3 times a day, for children over 6 years old - 1 tablet (0.2 g) 1-3 times a day.
The course of treatment is 2-4 weeks, can be repeated if necessary.
Side effects
Mild nausea, diarrhea, constipation, abdominal pain
Hypercalcemia, hypercalciuria
Allergic reactions
Contraindications
Hypersensitivity to the components of the drug
Hypercalcemia
Severe hypercalciuria
Thrombosis, thrombophlebitis
Severe atherosclerosis
Increased blood clotting
Severe renal failure
Children under 6 years old
Drug interactions
When used together, calcium preparations can potentiate the therapeutic and toxic effects of cardiac glycosides, increase the absorption of tetracyclines and reduce the absorption of bisphosphonates from the gastrointestinal tract. Glucocorticosteroids reduce calcium absorption. Concomitant use with thiazide diuretics or calcium-containing drugs increases the risk of developing hypercalcemia. Loop diuretics On the contrary, they increase the excretion of calcium by the kidneys.
It is recommended to combine with iron supplements. When used in patients receiving cardiac glycosides and/or diuretics, as well as during long-term treatment, the concentration of calcium and creatinine in the blood should be monitored. If their concentration increases, the dose of the drug should be reduced or temporarily stopped taking it. Due to the fact that vitamin D3 increases the absorption of calcium from the gastrointestinal tract, in order to avoid calcium overdose, it is necessary to consider the intake of vitamin D3 and calcium from other sources.
Absorption of calcium from the gastrointestinal tract may be reduced by concomitant intake of certain foods, such as spinach, rhubarb, bran and grains.
Special instructions
Pregnancy, lactation period
Calcium is excreted in breast milk, which should be taken into account when prescribing the drug to women during lactation. If the child is taking vitamin D3, the woman should stop taking calcium glycerophosphate.
The use of the drug during pregnancy and lactation is possible if the benefit/risk ratio in the mother exceeds the potential risk for the fetus or infant.
Features: the effect of the drug on the ability to drive vehicles or potentially dangerous mechanisms
Does not affect
Overdose
Symptoms- increased side effects
Treatment - stop taking the drug. Calcitonin is used as an antidote, which is administered intravenously at the rate of 5.0 - 10.0 IU per 1 kg of body weight per day.
Release form and packaging
10 tablets per blister-free packaging. Outline packaging along with the appropriate number of instructions for medical use or inserts are placed in a corrugated cardboard box.
Storage conditions
Store at temperatures from 15 0 C to 25 0 C.
Keep out of the reach of children!
Shelf life
Do not use after expiration date
Conditions for dispensing from pharmacies
Over the counter
Manufacturer
Lugansk, st. Kirova, 17
PJSC "Lugansk Chemical and Pharmaceutical Plant", 91019, Ukraine,
Lugansk, st. Kirova, 17
Address of the organization that accepts claims from consumers regarding product quality in the territory of the Republic of Kazakhstan
IP Tleubergenova G.S., Republic of Kazakhstan, 010000, Akmola region.
Astana, st. Bosingen 8, tel.
