Acetylsalicylic acid is included in the list of the most important medicines not only of the Russian Federation, but also of the World Health Organization.
Acetylsalicylic acid was first synthesized in 1853, and in 1887 this medicine was patented by the German company Bayer under trade name"Aspirin".
| Manufacturer | Commercial name drug | Country | Release form | Dosage |
| Update | Acetylsalicylic acid | Russia | Pills | Acetylsalicylic acid is usually prescribed to adults and children over 14–15 years of age. For fever, as well as to relieve mild or moderate pain syndrome 40-1000 milligrams of aspirin are used one-time. The frequency of use should be from 2 to 6 times a day at intervals of at least 4 hours. The maximum daily dosage should not exceed 3 grams. Aspirin is taken immediately after meals. As an analgesic drug, the course of treatment should not exceed 7 days, and as an antipyretic drug - 3 days. |
| Pharmstandard-medicines | Acetylsalicylic acid | Russia | ||
| Dalkhimpharm | Acetylsalicylic acid | Russia | ||
| Moscow pharmaceutical factory | Acetylsalicylic acid | Russia | ||
| Bayer | Aspirin | Germany | ||
| Obolenskoe | Russia | Enteric-coated tablets | ||
| Bayer | Aspirin cardio | Germany | ||
| Obolenskoe | Acetylsalicylic acid cardio | Russia | Capsules | |
| Bayer | Aspirin-S | Germany | Effervescent tablets | |
| Bayer | Aspirin complex | Germany | Included in combination drug for the treatment of acute respiratory diseases (acute respiratory infections). Prescribed for adults and children over 14–15 years of age. The medication is taken one sachet every 6 to 8 hours. You can take no more than 4 sachets per day at intervals of at least 6 hours. The course of treatment lasts, on average, 3 – 5 days. |
Acetylsalicylic acid, like other drugs from the group of non-steroidal anti-inflammatory drugs, has combined action. The antipyretic effect of aspirin is based on its ability to influence the thermoregulation center, which is located in the hypothalamus. Aspirin is able to shift the body temperature regulation point to a lower one. Subsequently, there is an increase in heat transfer processes and a decrease in heat generation processes ( increased sweating, expansion of peripheral blood vessels, as well as increased ventilation).Aspirin also has a moderate anti-inflammatory effect. This action is possible due to the ability of the drug to bind to a special enzyme - cyclooxygenase. Cyclooxygenase is the main “supplier” of various biologically active substances ( mediators), which are involved in the inflammatory response ( prostaglandins). Aspirin irreversibly binds to the enzyme cyclooxygenase and inhibits the release of prostaglandins. Acetylsalicylic acid also reduces energy supply inflammatory process.
Painkiller ( analgesic) the effect of aspirin is based on the ability to reduce the concentration of bradykinin, which, in fact, is one of the main mediators that provide pain sensitivity in tissues. Also this effect is also achieved by reducing the production of prostaglandins, which increase pain.
Aspirin can be used as a blood thinner. By irreversibly binding to the enzyme cyclooxygenase, acetylsalicylic acid blocks the formation of not only prostaglandins, but also thromboxanes. These biologically active substances can constrict blood vessels, increase pressure inside the arteries, and also activate platelet aggregation ( process of gluing blood platelets together). Also, other mechanisms that allow aspirin to reduce the risk of blood clots are not fully understood. It is worth noting that acetylsalicylic acid is used to prevent thrombosis in persons who have suffered a myocardial infarction, stroke, or those with vascular atherosclerosis.
| Name of pathology | Mechanism of action | Dosage |
| Rheumatism
(a systemic disease that primarily affects the heart) | It has antipyretic, analgesic, anti-inflammatory and antiplatelet effects. Cups ( eliminates) fever due to the effect on the hypothalamus and lowering the point of regulation of body temperature, as well as by increasing the process of heat transfer. The analgesic effect is achieved by suppressing the effects of the main biological active substance, providing pain sensitivity in tissues, and also due to a decrease in the production of prostaglandins. The anti-inflammatory effect is achieved mainly due to the irreversible binding of the cyclooxygenase enzyme and suppression of the secretion of prostaglandins, which contribute to the development of the inflammatory response. The blood-thinning effect is based on reducing the production of thromboxanes, which significantly reduces the chance of blood clots in the veins and arteries. | Daily dosage for adults is 2–4 grams per day ( depending on the severity of the disease). A single dosage for children one year old is 50 milligrams, from two years old 100 milligrams, from three years old 150 milligrams and at the age of four years it is 200 milligrams of aspirin. |
| Rheumatoid arthritis
(disease connective tissue, which affects small joints) |
||
| Infectious-allergic myocarditis
(inflammation of the heart muscle) |
||
| Fever | Children over 14 - 15 years of age and adults are prescribed orally after meals. A single dose of the drug is 250 – 500 milligrams ( sometimes 1 gram). Frequency of reception acetylsalicylic acid– three or four times a day. For children, a single dose, depending on the current age, is 100 – 300 milligrams. | |
| Headache | ||
| Menstrual pain | ||
| Toothache | ||
| Muscle pain | ||
| Prevention of blood clots | Single dose are selected individually. The daily dose should be 100 – 300 milligrams of aspirin. In some cases, the drug can be taken every other day, but it is necessary to take a dose of 300 milligrams. | |
| Prevention of myocardial infarction | ||
| Prevention of the development of cerebrovascular accidents |
Aspirin can be taken either alone or as part of various medicines. To reduce overall body temperature during fever, as well as to relieve various pain sensations ( headache, toothache, muscle pain, nerve pain) take 40–1000 milligrams of aspirin one time ( the dose is selected individually). Tablets must be taken at intervals of 4 to 6 hours. Maximum dose, which can be consumed per day is 3 – 4 grams ( overdose leads to damage to the brain, liver, kidneys, lungs). Aspirin is recommended to be taken after meals. To relieve fever, the drug should be used for no more than 3 days, and to reduce the severity of pain - no more than a week. Allergic rhinitis, or hay fever, is nothing more than inflammation of the nasal mucosa. Given this allergic reaction Nasal congestion, swelling, itching of the mucous membrane of the nasal passages and frequent sneezing are observed.
Angioedema, or Quincke's edema, as well as urticaria is one of the most common manifestations drug allergies. For Quincke's edema skin, as a rule, does not blush. This form of allergy affects the deeper layers of the skin ( unlike urticaria), namely the subcutaneous fatty tissue of the eyelids, lips, oral cavity, cheeks, genitals, and sometimes limbs. Swelling, as a rule, disappears within a few hours after its occurrence. Quincke's edema may be accompanied by symptoms such as nausea, vomiting, and pain in the upper abdomen.
Respiratory distress syndrome is a life-threatening condition in which a diffuse inflammatory process occurs in the lungs ( most of it is affected lung tissue ). Initially, shortness of breath and a dry cough occur. Pathological processes lead to the accumulation of inflammatory fluid in the lungs ( exudate). Subsequently, the gas exchange process in the lungs is disrupted, which contributes to the development of respiratory failure.
Anaphylactic shock represents one of the most dangerous forms drug allergies, since if you do not provide assistance to the victim in a timely manner, there is a high probability of death. Anaphylactic shock is characterized by the release of histamine in very large quantities, which leads to poor circulation in organs such as the liver, lungs, heart and brain. This condition manifested by decreased blood pressure, increased heart rate, urticaria and cyanosis ( the skin and mucous membranes acquire a bluish tint).
It is worth noting that it is highly undesirable to prescribe acetylsalicylic acid for the treatment of fever caused by various viral diseases ( chickenpox, measles, influenza) children under 12 years of age. This is due to the fact that in in this case An extremely life-threatening complication may occur - Reye's syndrome. The main manifestations of this pathology are cerebral edema and liver damage ( fatty infiltration). Reye's syndrome occurs due to disruption of certain metabolic processes. These disorders lead to damage to cellular components ( mitochondria), which are responsible for providing energy to various processes. Approximately 4 – 6 days after viral disease children appear severe vomiting which does not bring relief. There is also a violation mental state up to coma. The mortality rate for Reye's syndrome is approximately 25–30%.
| City | Average cost of the drug | ||
| Acetylsalicylic acid | Aspirin | Aspirin cardio | |
| Moscow | 4 rubles | 5 rubles | 141 ruble |
| Kazan | 3 rubles | 4 rubles | 137 rubles |
| Krasnoyarsk | 3 rubles | 4 rubles | 135 rubles |
| Samara | 3 rubles | 5 rubles | 134 rubles |
| Tyumen | 6 rubles | 8 rubles | 144 rubles |
| Chelyabinsk | 6 rubles | 9 rubles | 146 rubles |
Latin name: Aspirin®
ATX code: N02BA01
Active ingredient: acetylsalicylicum acidum
Manufacturer: Bitterfeld (Germany),
Chemica Pharmaceuticals (Spain),
Nizhpharm (Russia), Perrigo (USA)
Conditions for dispensing from a pharmacy: Over the counter
Most people try to use multicomponent drugs for pain, colds, and fever. At the same time, they forget about such an effective and effective means like Aspirin tablets. Typically, pharmaceutical innovative compounds are not cheap, compared with ordinary acetylsalicylic acid - budget option. It copes well with chills and helps with colds, so there is no need to take antiviral tea bags. It is prescribed to children, but there are a number of diseases when the drug cannot be taken.
The drug Aspirin belongs to the group of symptomatic drugs that are prescribed for pathologies and conditions accompanied by pain and fever:
The manufacturer produces several forms of the drug, and almost all types of Aspirin are combined. The usual drug is a tablet, the active ingredient of which is salicylic ester of acetic acid in a volume of 500 mg. Additionally, starch and cellulose are used as fillers.
The product refers to non-narcotic analgesics soft type of action. It can be found in almost every home medicine cabinet; the medication has a reputation as a safe medicine. The history of Aspirin goes back more than 150 years. Initially, it was found that willow bark contains salicyl, which is an excellent pain reliever. It is a fine-crystalline yellowish substance with a bitter aftertaste. Subsequently, Italian scientists obtained this substance by synthesis, but in an unrefined form. They separated the element into sugar and aldehyde, after which salicylic acid was obtained through hydrolysis and oxidation.
But the problem was that the resulting composition had a negative effect on the gastric mucosa. Therefore, pharmacists tried several times to improve the formula in order to obtain a safer compound using buffering. In the mid-19th century, the French scientist C.F. Gerhadt neutralized the acid using sodium and acetyl chloride. But the project was suspended for 40 years, and then the German concern Bayer rediscovered the formula, and the drug was intended for arthritis. Registered it as Aspirin m.n.s. full description already in 1900. But the medicine was sold only in powder form. The tablet form was created 4 years later.
It was at this time that the anti-inflammatory and antipyretic properties of the drug were discovered. And only 80 years later it was discovered that regular use of Aspirin orally can reduce the symptoms of unstable angina, which lead to myocardial infarction. Due to this, the risk and quantity deaths have decreased significantly.
As a result of repeated research and chemical reactions It was recognized that the product alleviates the condition of fever, relieves pain and eliminates inflammation. It belongs to the group of non-steroidal drugs, as it can act similarly to Diclofenac and Ibuprofen. The active substance inhibits the production of cyclooxygenase compounds, interferes with the metabolism of arachidic acid and prevents the synthesis of prostaglandins and thromboxanes.
By inhibiting the production of adenosine triphosphates, the element reduces hyperemia, reduces the secretion of exudate, increases the permeability of capillary walls, and blocks the activity of hyaluronidase. Thus, it creates conditions that limit the inflammatory process. In addition, acetylsalicylic acid affects neurons, controlling the functions of thermoregulation and sensitivity. A decrease in temperature occurs as a result of increased sweating and dilation of blood vessels.
It is believed that the main factor causing painful sensations, bradykinin acts. This is a peptide that is part of amino acids and belongs to the kinin protein group. It is a plasma dibenzoxyziline irritant of complex action, which at a concentration of 2 mg provides discomfort, and at 20 mg already causes unbearable pain. Aspirin, even in low dosages, can reduce the activity of bradykinin and alleviate the patient’s condition.
By reducing the production of thromboxane, aggregation is suppressed, so the vessels are able to dilate. The effect lasts for a week after taking the drug. The drug increases the fibrinolytic properties of plasma and normalizes blood clotting. Thanks to these qualities, the drug is actively used to treat strokes, ischemia and heart attacks. For thrombophlebitis and damage to arterial walls, as well as after surgery on the veins, the drug must be taken for life.
Also, recent studies have shown that the medicine helps with hypertension, as it regulates blood pressure. Its action is aimed at preventing diabetes. Oncological diseases. But it should be borne in mind that exceeding the daily dose of Aspirin can also lead to rupture and damage to blood vessels, which can lead to gastric bleeding.
With any intoxication, and especially alcoholic, the properties of the blood change. It becomes more viscous, so acetylsalicylic acid is great for overcoming a hangover. It prevents the formation of clots and blood clots, relieves swelling and intracranial pressure. Thanks to her, aching joints and headaches go away. But it is better to take the tablets in combination with other drugs. You should also not forget about recovery water balance. Important point The problem is that regular black tea and Aspirin are incompatible, so you should drink plain, slightly acidified water.
As for use in children, the drug is contraindicated under 15 years of age. This is associated with the risk of acute hepatic encephalopathy, the etiology of which is not fully understood. One version is a side effect due to the use of acetylsalicylic acid for the treatment of fever of viral origin. There is an American form - children's Aspirin, but this medicine is not available on the domestic market. Therefore, for children with chills and colds It is better to drink tea with honey or raspberries, unless it is contraindicated due to allergies.
It is important to cancel the value and benefits of the drug in cosmetology. For treatment acne, acne, comedones and pimples, it is recommended to use not only orally, but also externally. The composition is useful for skin prone to redness and increased oil production. It helps with dysfunction sebaceous glands and tightens the fading integument. Basically, salicylates are used as part of peeling masks. They interact well with familiar foods - cottage cheese, honey, herbs. But you need to know that such masks and scrubs are not suitable for dry epidermis.
Cosmetologists also advise using medicine to eliminate corns. In combination with lemon juice the acid quickly reduces callus tissue, while eliminating pain and inflammation. Also, tablets are often taken with you to the pool. Water containing greater concentration chlorine is bad for hair and skin.
Salicylate helps soften harmful effects and protect against infection. If you have been bitten by a wasp or mosquito, you can eliminate the swelling and pain with regular aspirin. If the drug is not at hand, willow bark, a precursor of the active substance, will come in handy. A decoction is made from it and applied to the affected area. In addition, it can be taken as a medicinal tea.
The drug should be taken orally with liquid. It is absorbed quickly, absorbed into upper sections intestines. During absorption, it undergoes a process of natural excretion through the walls of the organ; deacytylation occurs in the liver. Since hydrolysis is carried out with the participation of esterases, the evacuation period lasts no more than half an hour.
The main thing in the bloodstream active substance binds 85% to albumin. Distributed throughout tissues and fluids in the form of anionic acid. Maximum concentration achieved 120 minutes after administration. During reactions, metabolites are formed in the liver, which are necessary for the functioning of all systems. Excretion is carried out through the kidneys. The duration depends on the pH. With an alkaline cycle, the gap increases and reabsorption worsens.
Cost: Aspirin tablet 500 mg No. 10 – 30-40 rubles. No. 20 – 50-60 rub.
The manufacturer offers the product only in tablet form. In other forms, for example, as a solution in ampoules, it is prepared in combination with other medications (Analgin). Usually the medicine is packaged in plastic jars or aluminum strips of 5 pieces. The composition is odorless, but has a sour taste. The tablets are white, round, the company logo is embossed on both sides. The box is white and green, it contains a bottle or blister of Aspirin 500 mg, instructions for use. There is also a pack that contains two plates. Due to the peculiarity of acid affecting the mucous membrane, the drug is not available in syrup form.
Before starting treatment with medication, you need to check with your doctor whether Aspirin is taken before or after meals. Due to the fact that acid has a negative effect on the gastric mucosa, oral administration should be carried out only half an hour after breakfast or dinner. The dosage ranges from 300 to 1000 mg at a time, but not more than 4,000 mg per day. The course of treatment is 5 days, it can be extended only as prescribed by a doctor. Wash down the mixture with milk or jelly; tea is not suitable in this case.
The drug is contraindicated in the first and last trimester and during lactation. In some cases, the doctor considers prescribing medication appropriate, but constantly monitors the condition expectant mother and fruit.
Despite the fact that the drug has been recognized as relatively safe, there are pathologies and conditions for which it should not be taken:
The drug can both enhance the effects of various medications and lose its properties when interacting:
If you take the composition simultaneously with alcoholic drinks, the harmful effects on the gastric mucosa are enhanced many times over.
In most cases, the medication is well tolerated, but may cause negative reactions, if contraindications have not been taken into account. This is an attack bronchial asthma, allergic manifestations on the skin. In addition, some patients opened stomach bleeding which were accompanied by anemia, general weakness, abdominal pain and specific diarrhea. Dysbacteriosis of the oral mucosa and impaired zinc and copper metabolism were also observed.
If the recommended amount of 4,000 mg is exceeded, intoxication occurs. IN medium degree it is expressed in nausea, vomiting, pain in the stomach. Rapid breathing and increased sweating appear. First aid is to lavage the stomach with activated charcoal.
Severe overdose is accompanied by acidosis, hypoglycemia, and respiratory failure. In such cases, the patient must be urgently hospitalized. He is taken to intensive care, where they symptomatic therapy, measures to stabilize the condition. If necessary, hemodialysis is started.
The pharmaceutical product can be used for 5 years. It is necessary to protect from light and moisture, do not give access to children.
There are a number of medicines containing acetylsalicylic acid. This group includes the most well-known compounds:
Manufacturer: Vertex (Russia)
Price: tab. 100 mg No. 30 - 60-70 rub.
The drug is a tablet medicine, highly soluble in water, made according to a special formula. It contains acetylsalicylic acid and additional components for shell formation: lactose, starch, cellulose, flavorings, preservatives and dyes. It has a sweet and sour taste, but has no odor. When immersed in water, it instantly dissolves with a hissing sound. The tablets are round, packaged in double-sided blisters with a transparent surface. The pack contains two plates and an annotation.
Aspicor is intended for the treatment of lumbago, neuralgia, and arthralgia. By blocking the activation of cyclooxygenases and inhibiting the synthesis of prostaglandins, the main element eliminates inflammation, removes swelling, and relieves pain. He is also capable of causing increased sweating and dilation of blood vessels, which helps lower the temperature. The dosage is 0.5-3 g, divided into three doses. The amount depends on the condition and age of the patient. The duration of the course should not exceed two weeks.
Advantages:
Flaws:
Manufacturer: AKO Sintez (Russia)
Price: tab. 100 mg No. 30 – 20-25 rub.
This medicine also contains acetylsalicylic acid. The difference is that the manufacturer produces it in a shell with castor oil. This helps protect the gastric mucosa from negative impact active element. Thanks to these properties, the process of dissolution and absorption occurs already in the intestines. The tablets are white, round, odorless, slightly bitter in taste. They are placed in 10 pieces in blisters. The pack includes 3 records and instructions. Prescribe medication for inflammatory processes accompanying thrombosis, in order to prevent recurrent heart attacks, to prevent pulmonary embolism. It is also effective for high cholesterol levels and helps normalize blood clotting in older people.
In high dosages, the composition is capable of relieving pain, eliminating inflammation, and lowering temperature. Contraindicated in heart failure, severe kidney pathologies, and the aspirin triad. The use of the medication is discontinued 2 weeks before surgery to prevent bleeding.
Advantages:
Flaws:
Aspirin is a “folk” medicine with many uses: it lowers the temperature, thins the blood, and moderates headaches (toothaches). Also, this wonderful pill has been taken since the 70s of the last century to prevent heart attacks, strokes and oncology. And housewives have long been able to use it even for preservation. Inexpensive and familiar medicine to everyone, time-tested: date of invention - 1838
Acetylsalicylic acid is still a medicine wide application. It is a pain reliever and anti-inflammatory drug used to treat:
Cases of childhood illnesses after taking aspirin during the flu put the antipyretic functions of this drug in second place.
The beneficial properties of aspirin include the antithrombotic and cardioprotective properties of acetylsalicylic acid.
By suppressing platelet aggregation (through inhibition of the production of thromboxane A2) and the synthesis of prostaglandins, acetylsalicylic acid prevents the development of thrombosis and cardiovascular pathologies.
Today, aspirin is often used as a prophylaxis against thrombosis and associated dangers to the heart and blood vessels.
For the discovery in 1971 and evidence of the thinning and cardioprotective properties of acetylsalicylic acid, John Vane, an English pharmacologist, received the Nobel Prize in 1982.
Prophylactic administration of small doses of acetylsalicylic acid reduces the risk of thrombosis in the coronary and cerebral arteries, which prevents heart attack, ischemic stroke and other cardiovascular diseases.
Chewing an aspirin tablet during a myocardial infarction gives the patient a chance to survive and is used in first aid.
A few words about the new season swine flu, in which the medical standard protocol does not recommend taking aspirin.
In 2016, it leads, by the way, not only to pneumonia, but also to thrombosis.
Leonid Zhabotinsky died from a complication of swine flu - thrombosis of the intestinal arteries. Maybe acetylsalicylic acid, on the contrary, would have saved the weightlifter?
If aspirin is contraindicated, other drugs should be used for thrombosis:
When choosing a medicine, you need to carefully study its composition, since a number of modern thinning drugs are based on the same acetylsalicylic acid: for example, cardiomagnyl, aspecard, cardopyrin.
Oxford University Professor Peter Rothwell, having examined a large group of patients, found that constant use of acetylsalicylic acid leads to a decrease in the incidence of:
Aspirin was taken for 5 years in small doses: 75 - 100 mg.
Later, the experiment was repeated on specific tumors and the actual effect of aspirin on gastrointestinal tumors was determined - the likelihood of cancer decreased by 20%. A reduction in the likelihood of cancer of other organs (breast, lung, etc.) when taking aspirin has not been proven.
The short duration of the effect was also established: as soon as the drug was stopped, the risk of developing cancer resumed.
Long-term prophylaxis with acetylsalicylic acid, even in small doses, can lead to intestinal gastroduodenopathy, duodenal and gastric ulcers, as well as gastrointestinal bleeding. Therefore, it is necessary to periodically take protectors for the gastrointestinal tract and monitor the level of platelets in the blood.
What is a benefit - the thinning properties of aspirin, becomes deadly in the presence of:
All these pathologies are contraindications for taking the drug.
One of the misconceptions common among the population: aspirin irritates the mucous membranes due to the acetylsalicylic acid it contains.
In fact, acetylsalicylic acid has nothing to do with side effects medications on the gastrointestinal tract - this effect is characteristic of absolutely all drugs from the NSAID series, which include aspirin.
The method of any NSAID is to block cyclooxygenase (an enzyme involved in the production of prostaglandins, which cause inflammatory processes).
There are two types of enzyme - COX-1 and COX-2.
In addition to the synthesis of prostaglandins, COX-1 also brings benefits - it protects the mucous membranes of the gastrointestinal tract, ensuring the proliferation (division) of epithelial cells.
Most drugs (and aspirin among them), except for selective ones that act selectively, block both types of enzyme, which leads not only to the relief of the inflammatory process, but also to the depletion of the protective mucous layer of the gastrointestinal tract and the subsequent development of erosion phenomena.
Selective drugs (movalis, nimesulide, celecoxib) inhibit only COX-2. They are less harmful to the gastrointestinal tract, but also have side effects. These NSAIDs are intended for long-term use and are used mainly for diseases of the joints and spine.
Second myth: A coated aspirin tablet with additives is less dangerous for the stomach and intestines than a regular one.
This bluff was intensively spread by pharmacologists, producing all sorts of variants of expensive “mild” aspirin - in a shell mixed with other elements, in particular, magnesium hydroxide:
In reality, despite the protective coating of the tablets, the harm from them to the stomach and intestines is exactly the same as from a regular aspirin tablet: side effect occurs not from direct contact of the drug with the surfaces of the gastrointestinal tract, but from its absorption into the blood. Therefore, regardless of the form in which NSAIDs are taken (intramuscularly, intravenously, orally or as a topical gel), only the absorption rate will be different - side effects will remain the same.
As a result, the drug is unwittingly considered almost the most dangerous of all NSAIDs.
In fact beneficial properties This medicine, as you have seen, has a lot, and the contraindications are relative:
Absolutely everyone has contraindications medical product, and they should always be carefully studied, and not take medicine indiscriminately, guided by the principle: the more pills I take, the healthier I will be.
In each home first aid kit There is acetylsalicylic acid - Aspirin. The medicine helps reduce fever, get rid of toothache or migraine, and it is also useful for the face. But for some categories of people this drug is strictly contraindicated. What features of the product should be taken into account during treatment?
Acetylsalicylic acid (ASA), name in Latin - Acetylsalicylic acid, white crystalline powder, belongs to the group of analgesics and antipyretics. In medicine it is used as a non-steroidal anti-inflammatory and analgesic, as an auxiliary drug against adhesions blood cells. The substance has a slight odor, is highly soluble in water and ethanol, and is included in more than 100 medications for various purposes.
Release form: tablets containing 100, 250, 500 mg of acetylsalicylic acid. Additionally, the composition contains ingredients that do not affect therapeutic effect drug. You can buy acetylsalicylic acid tablets at any pharmacy without presenting a prescription, the price does not exceed 20 rubles.
Popular preparations of acetylsalicylic acid:
Pay attention! Aspirin is compressed acetylsalicylic acid plus cellulose and corn starch. There is no difference in the therapeutic effect between the drugs; the cost and manufacturers may differ, so you can safely buy cheaper analogues.
After taking acetylsalicylic acid into the body, hyperemia decreases, capillary permeability at the site of inflammation decreases - all this leads to a noticeable analgesic and anti-inflammatory effect. The drug quickly penetrates into all tissues and fluids, absorption occurs in the intestines and liver.
Action of acetylsalicylic acid:
The drug can be taken to prevent thrombosis and reduce the risk of developing circulatory disorders in the brain.
Pay attention! The antiaggregation effect of ASA is observed for 7 days after a single dose of the drug. Therefore, you should not drink the product before surgical interventions, shortly before menstruation.
Regularly taken acetylsalicylic acid inhibits (inhibits) the formation of blood clots (thrombi), which can close the lumen of the artery. This reduces the risk of heart attack by almost half Due to its wide spectrum of action, acetylsalicylic acid is used for the treatment and prevention of diseases of various etiologies in adults, children over 15 years of age.
What does acetylsalicylic acid help with:
ASA is included in complex therapy in the treatment of pleurisy, lumbago, heart defects, prolapse mitral valve. This drug is recommended for use when the first signs of flu or cold appear - it helps increased sweating, which leads to rapid improvement condition.
Advice! Aspirin is one of the the best means to eliminate the consequences of a hangover, the drug thins the blood, eliminates headache and swelling, reduces intracranial.
Acetylsalicylic acid is popularly called aspirin or a universal headache tablet. It is an anti-inflammatory and antipyretic agent The instructions for acetylsalicylic acid detail all contraindications and possible negative consequences when taking the drug. Before you start using the product, you should carefully study the instructions to avoid serious complications.
Contraindications:
You should not drink acetylsalicylic acid if you are hypersensitive to salicylates, while taking Methotrexate, and should not be taken simultaneously with alcoholic beverages or ethanol-based medications.
Most negative consequences while taking ASA it is associated with the digestive system - most often patients complain of pain in the epigastric region, nausea, vomiting, etc. During treatment, pain in the head may intensify, tinnitus may appear, and organ function may deteriorate. urinary system. If you are prone to allergies, a rash, bronchospasm, and swelling may occur. In rare cases, erosions and ulcers develop in organs digestive tract, renal or liver failure. But if patients take the medicine strictly following the instructions, then adverse reactions rarely appear.
Do not take acetylsalicylic acid together with other non-steroidal drugs anti-inflammatory action, anticoagulants, Aspirin reduces the therapeutic effect of diuretics.
Pay attention! At long-term use ASC often causes a temporary deterioration in hearing and vision. The consequences are reversible and go away on their own after discontinuation of the drug.
Acetylsalicylic acid is contraindicated in children under 14 years of age, since the drug can displace bilirubin, which can cause the development of severe kidney and liver pathologies in infants and preschoolers and adolescents. Pediatric dosage: 250 mg twice daily, maximum allowed daily dose is 750 mg.
Acetylsalicylic acid is strictly prohibited during pregnancy in the first trimester - the drug has a teratogenic effect and can provoke development in the child birth defects heart, cleft palate.
Pay attention! ASA often becomes the cause in the early stages.
You should not take acetylsalicylic acid or paracetamol in III trimester- the drug causes pulmonary hypertension in the fetus, which causes the development of pathologies in respiratory tract, blood flow disorders. Using ASA at this time can provoke severe uterine bleeding.
During breastfeeding ASA cannot be taken, since the acid penetrates into the milk, which can lead to a deterioration in the baby’s health and the development of severe allergic reactions.
During the second trimester, admission is possible, but only in the presence of acute indications and with the permission of the doctor; in the last period of gestation, admission is completely prohibited ASA should be taken only after meals so as not to cause deterioration in performance digestive system You can drink it with still water or milk. The standard dosage is 1-2 tablets 2-4 times a day, but not more than 1000 mg at a time. You can take no more than 6 tablets per day.
How to take ASA for certain pathologies:
Advice! Take Aspirin when slight increase arterial parameters, if there are no antihypertensive drugs at hand.
Acetylsalicylic acid can be used in homemade recipes for face masks, hair restoration, and dandruff removal.
Acetylsalicylic acid effectively helps against - grind 3 tablets of ASA into powder, add 5 ml of liquid and fresh aloe juice. Mixture thin layer Apply to steamed skin and leave until completely dry. Before removing the composition, you need to massage the dermis with light movements and wash warm water. Carry out the procedure twice a week.
Recipe for an anti-wrinkle mask with acetylsalicylic acid - dissolve 6 ASA tablets in 5 ml of lemon juice, add 5 g of fine salt, blue clay and honey. The skin should first be steamed and the mixture should be applied for a quarter of an hour. Sessions are held every 2-3 days.
To reduce oily hair and eliminate dandruff, one Aspirin tablet should be added to a portion of shampoo. Use remedy maybe once a week.
Acetylsalicylic acid is an affordable and effective remedy to eliminate pain and inflammation. The drug has not only wide range actions, but also many contraindications, so you should first consult with your doctor and carefully study the instructions for use.
Among widely used medicines, Aspirin is in great demand. People use this drug in medicinal purposes at various diseases, sometimes opposite to each other. What qualities does this medicine have?
The properties of aspirin are very multifaceted. No wonder this drug taken by people suffering from the following ailments:
Acetylsalicylic acid has a unique effect on the body. Its structure actively suppresses the activity of cyclooxygenase enzymes, which are involved in the formation of inflammatory centers (prostaglandins).
Timely administration of this drug reduces the energy reserves of the processes, against the background of which the latter begin to attenuate. Such healing effect very important in situations related to the development of rheumatic diseases in the body.
The main component of aspirin is acetylsalicylic acid. Its properties are aimed at eliminating the source of pain and lowering body temperature. Analgesic and antipyretic effects arise as a result of the inhibitory effect of acetylsalicylic acid on central areas in the brain.
Against what background does it disappear? pain sensitivity and thermoregulatory processes are normalized. Based on this, patients with high fever are given a tablet of the described medicine.
Aspirin tends to influence the activity of blood platelets. This medicine reduces the ability of blood to stick together, which reduces the likelihood of blood clots. As a result, the blood becomes more diluted, and the vascular lumens increase.
This has a positive effect on general condition body, taking into account increased level intracranial pressure.
For all its versatility, Aspirin is recommended to be taken in doses and when necessary.
The benefits of using Aspirin for medicinal purposes are noticeable to the naked eye.
This cardiac medication is classified as a non-steroidal anti-inflammatory substance. Penetrating into the body, the active compound of Aspirin eliminates the processes of synthesis of prostaglandins with thromboxanes in an irreversible way.
The antipyretic effect of taking the described tablets is achieved by normalizing thermoregulatory processes controlled by brain cells. The analgesic effect begins with the effect of acetylsalicylic acid on inflammatory mediators located in the central nervous system.
Once in the blood, the active compounds of the drug prevent platelet clotting, resulting in a decrease in blood viscosity. And the blood vessel also expands.
Anti-inflammatory properties are produced due to a decrease in permeability of small capillaries located in the painful area. Against this background, the formation of inflammatory agents stops, which limits access to cellular energy reservoirs.
From all of the above we can conclude that pharmacological effect very versatile and effective.
The described medicine helps reduce the risk of circulatory disorders that feed brain cells during ischemia.
Regardless of the nature of the origin of myocarditis (allergic or infectious), acetylsalicylic acid copes with the disease.
Damage to the body by infectious and inflammatory diseases is accompanied by an increase in temperature, which the described tablets can reduce.
Acetylsalicylic acid is effective in rheumatoid arthritis with manifestations of rheumatism.
With the help of acetylsalicylic acid, it is possible to rid the body of various headaches associated with neuralgia or myalgia.
Aspirin prevents blood from thickening and the formation of emboli with blood clots inside it.
This drug is an excellent prophylactic against myocardial infarction.
Aspirin should be taken as prescribed by a doctor or based on the instructions. For each disease, a specific dose of medication and frequency of administration have been developed.
For adults, a therapeutic dose of the drug in one dose is considered to be from 40 mg to 1 g. In some cases, up to 6 tablets of medication are taken per 24 hours during the day. This should be done on a full stomach, since acetylsalicylic acid can have a detrimental effect on its mucous membrane.
If you take these tablets without a doctor’s prescription, the duration of the treatment course should not be more than a week until the analgesic effect is achieved.
With great caution, this medicine is used to treat people with symptoms of gout. Before using the described medication for treatment, you must consult a doctor or familiarize yourself with the contraindications to the drug.
This medication should be taken in certain doses prescribed by the doctor or taken from the instructions. This will save a person’s health from harm that can be caused by an incorrectly taken medication.
When treating with Aspirin, you should not get carried away with drinking alcohol. This can provoke the development of attacks of bronchial asthma or bronchospasms.
Drink Aspirin with a small amount of water or milk after meals. If necessary, the tablet is divided into shares or drunk completely. High temperature body requires simultaneous administration of not just one tablet, but 2 or more. It is not recommended to take more than 3000 milligrams of acetylsalicylic acid per day (no more than 6 tablets).
