Diclofenac is a solution of eye drops based on phenylacetic acid, a non-steroidal anti-inflammatory drug. Used in ophthalmology to treat inflammatory processes anterior segment of the eye of a non-infectious nature, including processes of inflammation after eye surgery, inhibition of miosis in cataract surgery, pain relief in excimer laser surgery. Effective for the prevention of cystoid edema of the optic nerve during operations involving lens removal.
Diclofenac is a solution of eye drops 0.1%, light yellow, transparent, sterile, contains:
Package. Polymer bottles with a dropper, 5 and 10 ml in a cardboard pack.
Diclofenac solution is a topical NSAID based on phenylacetic acid with anti-inflammatory and analgesic effects.
By indiscriminately inhibiting COX-1, COX-2, diclofenac sodium disrupts the metabolism of arachidonic acid, reducing the number of prostaglandins at the site of inflammation. When applied topically, it relieves swelling and pain syndrome. Prescribed for the treatment of inflammatory processes of non-infectious etiology of the anterior segment of the eye.
Diclofenac solution is instilled conjunctivally 5 times, 1 drop each, within 3 hours before surgery (interval 20-25 minutes) and three times after surgery, 1 drop each, with the same interval. Then, for the required time, drop 1 drop up to 5 times a day. For other indications - 1 drop 4-5 times a day.
Diclofenac solution is prescribed with caution to elderly patients, persons with aspirin-induced asthma, epithelial herpetic keratitis (including history), with blood clotting disorders (hemophilia) and peptic ulcer stomach in the acute stage. According to indications, it can be prescribed until the third trimester of pregnancy, as well as for lactating women.
The interval after instillation of Diclofenac solution with other eye drops should be 5-10 minutes. If necessary, the drug can be combined with solutions containing glucocorticosteroids.
Treatment with Diclofenac solution requires refusal to use soft contact lenses. Hard contact lenses must be removed from the eyes before instillation of the drug. They can be returned to the eye 20 minutes after the end of the procedure.
Immediately after instilling Diclofenac solution, some patients experience visual disturbances (no more than 15 minutes). During this period, it is better to refrain from driving vehicles and working with moving mechanisms.
Store Diclofenac solution in a dark place at room temperature, do not give it to children. Shelf life - 3 years.
The eyes quite often suffer from fatigue and inflammation. They may be caused by illness or external factor, but it is always important to choose optimal treatment. One way to help your eyes is to use modern and effective drops Diclofenac.
A non-narcotic, non-steroidal drug used in ophthalmology for the treatment of post-traumatic and post-operative interventions. Quickly relieves the inflammatory process, suppressing the production of pathogenic bacteria. Due to inhibition of work and the appearance of prostaglandins, it effectively eliminates pain and relieves swelling in the area of inflammation.
The drug enters the anterior chamber of the eye within 15-30 minutes after administration and remains effective for several hours. Only a small part of the substance enters the main bloodstream, taking into account the correct dosage.
Included medicine contains several components, the main one of which is diclofenac. This substance belongs to the class of non-steroidal components that prevent the formation of inflammatory processes. To enhance the impact and maintain long-term results in the composition eye drops also includes:
The substances organically complement each other, promoting better penetration and eliminating the causes of inflammation and irritation.
The drug is available in two forms:
The first is used mainly in hospital treatment conditions, the second type of packaging is intended for use at home.
The main cases of taking Diclofenac drops include:
The drug is always instilled into the conjunctival sac in the area adjacent to the outer corner of the eye.
The exact course of treatment is drawn up by the doctor, taking into account aggravating factors and the patient’s medical history. The duration of use of Diclofenac cannot be more than 28-30 days. In rare cases, the course of treatment is extended from 7 to 21 days for very severe and complex forms of disease and swelling eyeball.
Side effects are most often observed with long-term use Diclofenac, in case of individual intolerance and in case of incorrectly calculated dosage. Side effects include:
Contraindications for the use of Diclofenac include:
Before taking the medicine you should know the following:
It is prohibited to use the drug during pregnancy, as it can cause blood flow problems in the fetus. In rare cases, if there is no other option, Diclofenac is prescribed in the third trimester of pregnancy if there is no benefit to the mother significant harm child. During lactation, breastfeeding is prohibited when taking Diclofenac.
| Analogue | Description | Approximate price |
|---|---|---|
| Phloxal | Is antimicrobial medicine, also applicable during the period postoperative treatment and to eliminate inflammatory processes. Thanks to its antimicrobial effect, Floxal quickly eliminates pathogenic bacteria and pain, prevents swelling and suppuration | 185 RUR |
| Stillavit | Drops based on panthenol, due to which they quickly restore damaged tissues and prevent neoplasms. Active substances quickly suppress the metabolism of the formation pathogenic bacteria what's in short terms relieves inflammation and swelling | 361 RUR |
| Tobradex | Drops based on the antibiotic thoramycin. Anti-inflammatory and antimicrobial effect achieved thanks to fast work antibiotic. Most often used in postoperative period or for the treatment of conjunctivitis | 329 RUR |
When taking Diclofenac, you should definitely coordinate treatment with your doctor to prevent complications and allergic reactions.
Diclofenac- This eye drops with a pronounced analgesic and anti-inflammatory effect.
Capable of quickly relieving severe pain, and also reduce inflammatory swelling at the site of the lesion.
Most often, these drops are used for the prevention and treatment of various types of inflammation of a non-infectious nature, post-traumatic inflammatory processes in the eyes, as well as in the case of cataract surgery.
The drug Diclofenac is a slightly yellowish or completely colorless liquid, which is intended exclusively for topical use.
The drug is used to prevent various inflammatory processes of infectious and non-infectious nature.
In addition, the drug has various effects such as:
Application this drug- a necessary measure. Home distinctive feature Diclofenac is fast and quite effective removal pain and inflammation. Symptoms caused by an eye infection go away even faster in this case.
The main mechanism of action of eye drops called Diclofenac is the suppression of the synthesis of substances that activate and maintain the process of inflammation in the affected area, reducing the severity of possible pain, gradually reduces the severity of possible inflammatory edema.
In terms of anti-inflammatory activity, this drug is significantly ahead of drugs such as aspirin (acetylsalicylic acid), ibuprofen and butadione.
In the cornea and conjunctiva this active substance after instillation of drops, it can reach its maximum concentration within thirty minutes. In the systemic circulation in high concentrations Diclofenac is not detected.
Diclofenac eye drops are used both for the prevention and treatment of various inflammatory non-infectious processes such as keratoconjunctivitis, corneal erosion, conjunctivitis, post-traumatic complications on the cornea, inflammation of the conjunctiva, photophobia.
They are used for the prevention and treatment of various post-traumatic inflammations immediately after any wounds of the eyeball (both penetrating and non-penetrating) as an addition to antibacterial therapy.
The drug Diclofenac is quite effective in the prevention of miosis during surgery due to cataracts and various processes inflammatory in nature immediately after any surgical interventions, for the prevention and treatment of cystoid macular edema immediately after cataract removal.
The drug Diclofenac is used exclusively topically. It should be instilled one drop four times a day for one to four weeks.
To inhibit pupil constriction in the case of surgical interventions, it is necessary to instill one drop of the drug Diclofenac into the conjunctival sac even before the operation. After this, for two hours, necessarily with breaks of 30 minutes (four times).
After cataract removal, it is necessary to instill one drop three times a day; the duration of this course of treatment should be determined by the doctor. Prevention of macular edema requires instillation of one drop of the drug per day four times for one month immediately after surgery.
Possible local reactions as a result of using the drug:
Digestive system: vomiting and nausea.
Possible allergic reactions: hyperemia, chills, itching of the eyes, angioedema of the face, fever, skin rash, urticaria, photosensitivity or exudative erythema multiforme.
One ml of this drug contains 1 mg of diclofenac sodium, as well as some auxiliary ingredients such as:
The release form of the drug is 0.1% eye drops in special dropper bottles with a total capacity of 5 ml; the package includes 1 dropper bottle and instructions for use. They are also produced in special dropper tubes with a total capacity of 1 ml, two tubes per package.
Experts do not recommend combining Diclofenac with diflunisal, as bleeding from the gastrointestinal tract, or with various NSAIDs (acetylsalicylic acid in doses /≥3 g/day) and drugs Methotrexate, Sulfonylurea.
The combined use of the drug Diclofenac with lithium preparations, indirect anticoagulants and digitoxin can lead to a gradual increase in their effect.
If necessary, Diclofenac can be used in conjunction with other eye drops that contain corticosteroids. In this case, the break between applications should be more than 5 minutes to prevent all active ingredients the following doses.
Diclofenac should not be prescribed to children under two years of age, as well as to women during pregnancy for more than 6 months.
These drops are used with extreme caution in cases of epithelial herpetic keratitis, bronchial asthma, possible violations blood clotting, as well as in adolescents under 16 years of age and elderly patients.
Up to 6 months of pregnancy, you can use the drug if there is a potential healing effect for the mother is much higher than the possible risks for the fetus. During treatment with these eye drops breast-feeding definitely stop.
During pregnancy, taking the drug is justified only if the potential benefit to the expectant mother outweighs the potential risk.
Breastfeeding should be discontinued while using the drug.
Taking Diclofenac eye drops can only mask some signs bacterial infection, which is why it is necessary to take into account the possible sudden development of a bacterial infection as a result of using the drug.
If this drug is used for a long time, it is necessary to carry out regular preventive examination eyes and control intraocular pressure.
During treatment you should not wear contact lenses. If it is impossible to refuse to wear contact lenses, you must remove them 5 minutes before instilling the medicine. After using the drug, contact lenses can be put back in 15 minutes.
If hypersensitivity reactions occur after taking the drug (itching, sudden swelling of the neck and face, redness or attack bronchial asthma), treatment must be stopped and immediate medical attention is required.
Patients with chronic rhinitis, bronchial asthma, chronic sinusitis have a risk of developing various allergic reactions when using aspirin or non-steroidal anti-inflammatory drugs.
Such anti-inflammatory drugs, as well as Diclofenac, inhibit re-epithelialization of the cornea even with short-term use. The risk of infection and the consequences of slow corneal healing have not yet been established.
Taking NSAIDs increases the risk of bleeding from eye tissue during surgery. Experts recommend that this drug be prescribed with extreme caution to patients with an increased risk of bleeding or to patients who are taking medications that can prolong bleeding time.
If NSAIDs are used in fairly large doses over a long period of time, keratitis may develop.
In some cases, with long-term use of Diclofenac by particularly susceptible patients, it is possible:
All of the above complications can affect visual function.
Store strictly away from light and out of reach of children, at temperatures from 15° to 25°C. Freezing is not allowed. After opening the bottle, it can be stored for no more than four weeks.
The shelf life of the drug is 2 years.
The average price of the drug "Diclofenac" in Russia is 30 rubles, and in Ukraine 9 hryvnia.
The following drugs are excellent analogues of this drug:
Probably everyone has encountered problems with eye fatigue or inflammation. It is very important to consult a doctor in a timely manner and take a course correct treatment. It is for such cases that there are special drugs in the form of drops.
Diclofenac is an eye drop that has an analgesic effect. They are great in situations of inflammation and mechanical damage organs of vision.
The product is available in the form of 0.1% drops in bottles with a dropper, which ensures easy and economical use of the drug.
The consistency of the medicine is liquid. Color - transparent with a hint of yellow. Diclofenac sodium is the main component of the drug. Excipients are:
The use of the medicine ensures the elimination of infectious diseases, while the drug does not enter the blood, but only accumulates in the tissues of the cornea. Diclofenac instantly relieves swelling of the eyes and restores the mucous membrane.
Indications:
Drops are contraindicated for use on their own. Consultation with your attending physician - an ophthalmologist is required. After prescribing the drug, the patient must carefully study the instructions and act strictly according to them. You should not use the medicine if:
It is also very important to consider the patient's age. Special dosages are intended for children under 12 years of age and older people (read the instructions for Diclofenac eye drops in more detail).
The instructions for using Diclofenac eye drops state that for conjunctivitis, use 1 to 2 drops of the drug up to 5 times a day. However, the dosage and duration of treatment are prescribed by an ophthalmologist, based on the characteristics of the body and the degree of the disease.
If carried out surgery, the medicine is dripped every hour for five hours. The next day, the drug is taken according to the instructions.
The course of treatment depends on the diagnosis. In order to prevent swelling of the central part of the retina, drops are prescribed for seven days, 3 to 4 drops per day.
During inflammation (without infection) - 2 drops, three to four times a day.
Drops should not be used during the 1st trimester of pregnancy. In subsequent trimesters, the drug can be taken only after a visit to the doctor. The treatment is short-term and carried out under the supervision of a specialist.
During lactation, medication can also be taken under the supervision of a doctor.
If the medicine is used strictly according to instructions, the risk side effects null. If the dosage is incorrect, the following side effects have been identified:
During treatment, you should stop wearing contact lenses. Elderly people should use the drug strictly as prescribed by a specialist in order to avoid unwanted side effects. Also not recommended for treating children under 6 years of age.
Instructions for use state that alcohol consumption should be avoided during the treatment period. Also, during treatment you should stop driving a car, as there may be a temporary deterioration in vision.
Analogues of Diclofenac are Diphtal drops (imported), Voltaren Ofta, Diclofenaclong. These drugs are similar in pharmacological actions. However, Diclofenac is most effective in combating inflammatory processes in the organs of vision.
active ingredient: diclofenac sodium - 1.0 mg/ml;
auxiliarysubstances: sodium thiosulfate, disodium edetate, propylene glycol, boric acid, potassium chloride, sodium hydroxide, water for injection.
Medicines used in ophthalmology. Non-steroidal anti-inflammatory drugs.
ATS code: S01BC03.
Pharmacological action
Has anti-inflammatory and analgesic effects. In inflammatory processes that occur after operations, it relieves pain and reduces inflammatory swelling at the wound site.
Inhibition of miosis during cataract surgery; prevention of inflammatory processes associated with surgical removal cataracts or surgery in the anterior segment of the eye; reduction of pain and photophobia after keratectomy during the first 24 hours after surgery.
Adults:
Inhibition of miosis during cataract surgery‘
Prevention of inflammatory phenomena associated with surgical removal of cataracts or surgery in the anterior segment of the eye: Before surgery: Instill up to five times within three hours before surgery.
After surgery: 3 drops at the end of the intervention, then three to five times a day. It is not recommended to use the drug for more than 4 weeks.
Reduction of pain and photophobia after keratectomy within 24 hours after surgery:
Within one hour before surgery, 1 drop 1-2 times, after surgery, 1 drop 2 times within an hour, then 1 drop four times within 24 hours after surgery.
Children:
No special studies have been conducted.
Dosage in the elderly:
Before use, read this section carefully and follow the steps presented below in the text.
Remove the bottle from the packaging. Place the scissors at an angle of 45 degrees to the lid, picking it up bottom edge, using an upward motion, remove the aluminum cap along with the rubber cover. Remove the dropper from the packaging and place it tightly on the bottle. Turn the bottle vertically to remove any air bubbles and wait a few seconds. In the case of a large bubble, return the bottle to its original position, and then slowly repeat the action, gently tapping the bottom of the bottle. Apply instillation by pressing the pipette with your index finger and thumb. Turn the bottle over and close the pipette with a special stopper.
Before using the medicine, remove the protective cap from the dropper tube and cut off the membrane of the body neck with scissors without damaging the threaded part.
Wash your hands before instillation.
Tilt your head back.
Pull your lower eyelid down and look up.
Turn the body of the dropper tube with the medicine upside down and soft movement, pressing on the body of the dropper tube, drop 1 drop into the space between the eyelid and the eyeball.
Do not touch the tip of the dropper tube to your eyelids, eyelashes, or touch it with your hands.
Close your eye and pat it dry with a cotton swab.
Without opening your eyes, lightly press the inner corner for 2 minutes. This will increase the effectiveness of drops and reduce the risk of developing systemic adverse reactions. Wash your hands after use.
After use, keep the dropper tube tightly closed.
Side effectsoh action
The frequency of side effects is given in the following gradation: very often (≥1/10); often (≥1/100,
Infections and infestations: unknown - rhinitis.
Immune system: rarely – hypersensitivity reactions.
Eye diseases: infrequently – burning in the eye, blurred vision after instillation; rarely - punctate keratitis, thinning of the cornea, corneal ulcer; unknown - conjunctival hyperemia, eyelid edema.
Respiratory system: rarely – shortness of breath, provoking an attack of bronchial asthma; unknown - cough.
Skin and subcutaneous fatA: rarely – erythema, itching, photosensitivity reactions; unknown - urticaria, rash, contact dermatitis. Corneal thinning or corneal ulcers have been reported in rare cases, especially in patients with increased risk development, for example, when using corticosteroids in persons with concomitant rheumatoid arthritis. Most patients used the drug for long period time.
Post-marketing data indicate that in patients with complications from ocular surgery, corneal epithelial defects, diabetes mellitus, superficial diseases of the eye (for example, dry eye syndrome), rheumatoid arthritis, repeated operations on the eye for a short period of time, there may be an increased risk of developing side effects from the cornea.
In the event of the above adverse reactions or adverse reactions not listed in this instructiontions for medical usemedication, you must consult a doctor.
Contraindicationania
Increased individual sensitivity to diclofenac and other non-steroidal anti-inflammatory drugs, as well as to any of the auxiliary components of the drug, a history of allergic reaction or bronchial asthma caused by taking diclofenac, acetylsalicylic acid and other non-steroidal anti-inflammatory drugs, pregnancy, lactation, childhood(up to 18 years old).
WITH caution: epithelial herpetic keratitis (including history); diseases, causing disturbances blood clotting (including hemophilia, prolongation of bleeding time, bleeding tendency); old age.
There is no information about cases of overdose.
Do not administer parenterally, do not swallow. The drops should not be used as a peri- or intraocular injection. It is necessary to wash your hands thoroughly before instilling eye drops, avoid contact of the bottle or dropper tube with the eye or eyelid, and tightly close the bottle or dropper tube after use. The use of diclofenac sodium eye drops masks the signs of a bacterial eye infection, so the possibility of sudden development bacterial infection due to the use of the drug. With long-term use of the drug, it is necessary to regularly carry out preventive eye examinations, as well as monitoring intraocular pressure.
Wearing contact lenses is not recommended during treatment. If it is impossible to refuse to wear contact lenses, they should be removed at least 5 minutes before instillation of the drug and placed back no earlier than 15 minutes after instillation. If, after using the drug, hypersensitivity reactions occur, such as itching, redness, an attack of bronchial asthma or sudden swelling of the face and neck, treatment should be stopped, immediate treatment is necessary. Non-steroidal anti-inflammatory drugs, including diclofenac, inhibit reepithelialization of the cornea even with short-term use. The consequences of delayed corneal healing and the risk of infection have not been established. The use of NSAIDs increases the risk of bleeding from the eye tissue during surgery. It is recommended to prescribe the drug with caution to patients with an increased risk of bleeding or receiving drugs that may prolong bleeding time.
When using NSAIDs in large doses for a long time, keratitis may develop. In some particularly susceptible patients, long-term use of the drug can lead to disruption of the epithelial barrier, thinning of the cornea, corneal infiltration, development of corneal erosion and ulcers, and corneal perforation. These complications can affect visual function.
Corticosteroids are known to slow healing. Simultaneous use of NSAIDs and steroids may increase the risk of impaired regeneration.
Use during pregnancy and lactation
