Essentiale Forte in ampoules is cheaper. Essentiale analogues and prices

The occurrence of heaviness and pain in the right hypochondrium occurs when the activity of the liver or gallbladder of various etiologies is disrupted. Essentiale forte analogues will help start the recovery process and stop the destruction of the organ. The effectiveness of the original medicine is confirmed by doctors and patient reviews. What can you say about Essentiale's analogues?

Essentiale forte is a hepatoprotector used in medicine for the treatment and prevention of liver diseases. The drug minimizes the negative effects of other medications on the organ, restoring it.

The medicine is freely available and sold in the form of capsules and solution in ampoules. Capsules are in cardboard packaging containing blisters of 10, 12 and 15 pieces.

The main active component of Essentiale Forte are essential phospholipids, the maximum content of which in capsules is 300, and in solution - 250 milligrams.

As auxiliary components, Essentiale Forte includes:

  • hard fat, making it easier to swallow the medicine;
  • castor oil, which prevents constipation during therapy;
  • distilled water acting as a solvent;
  • dyes.

Essentiale and its analogue substitutes are prescribed to protect the liver from intoxication and other adverse factors.

When toxins enter the human body, the integrity of the membrane structures of liver cells is disrupted. This interferes with the performance of the initial functions of the organ.

The liver is capable of regeneration. It can be accelerated with the help of essential phospholipids. These substances are able to restore diseased areas of the liver in a minimum amount of time. That is why phospholipids are the main component of Essentiale.

Timely and correct treatment Essentiale has the following effects on the human body:

  1. Provides protection to hepatocytes from negative impact harmful factors.
  2. Cleanses the liver of toxins.
  3. Prevents intoxication of the body.
  4. Restores the structure of liver cells.
  5. Helps normalize metabolic processes.

Absorption of the active component occurs in small intestine. After this, phospholipids enter the bloodstream and are transported along it to the liver.

Maximum saturation of the blood plasma with the active component of the drug occurs 6-24 hours after the first dose of the drug.

Essentiale Forte is not an inexpensive medicine. Therefore, some patients choose analogues for treatment.

Russian analogues of the drug

The average cost of Essentiale Forte is from 600 to 850 rubles for 1 package with 30 capsules. Their domestic analogues cheaper.

Taking into account the financial capabilities of patients, doctors offer them the following replacements for Essentiale:

  1. Essliver forte. The cost of the medicine for 1 package does not exceed 550 rubles. The composition of the Essliver Forte substitute is identical to the original, containing phospholipids of natural origin. They are supplemented and vitamin complex, accelerating the process of cell regeneration in cirrhosis, liver damage caused by exposure to radiation, drugs, and alcohol. Essliver forte, analogues with other names, show high efficiency as prophylactic agents to prevent liver diseases caused by taking antibiotics. Treatment is carried out under the supervision of a specialist. The Essliver therapy regimen involves taking 2 capsules daily three times a day for 3 months.
  2. Livolin forte. This is a cheap Essentiale analogue, costing no more than 200 rubles. The active components of Livolin are phospholipids and lecithin. The main indications for use are: different types hepatitis, liver cirrhosis, liver failure and nephropathy.

The drug is taken three times a day, 1 capsule for 2 months. The duration of the course depends on the severity of the disease and the individual characteristics of the body.

Is in particular demand Russian analogue Essentiale forte Carsil. It is available. TO

The number of tablets consumed at a time can reach 4 pieces. Consumers find this inconvenient, as is the long course of treatment.

Generics from neighboring countries

Generics or substitutes for Essentiale Forte from neighboring countries are often represented by drugs of Belarusian and Ukrainian origin. The cost of analogues is lower than the price of Essentiale Forte.

  1. Essencecaps. Inexpensive analogue of Essentiale Forte. Country of origin - Belarus. The hepatoprotective effect of Essencecaps helps protect the liver from damage by alcohol, radiation, antibiotics, hormonal drugs And external factors. The drug is recommended by doctors for poor appetite, a feeling of pressing heaviness in the right hypochondrium and complex therapy serious diseases requiring simultaneous use of multiple medications.
  2. Antral. A medicine for liver diseases, belonging to the budget category. The average cost of a package of tablets is 400 rubles. Country of origin - Ukraine. The main active component of Antral is a complex of phospholipids. The drug is presented in tablet form and as a solution for injection.
  3. Larnamine. The medicine, which has a hepatoprotective effect, is intended to combat liver diseases, intoxication of the body and encephalopathy. Larnamin is more expensive than Essentiale and is available in the form of sachets and solution for intravenous administration.

Each of these medications has contraindications and side effects. This must be taken into account before using the products. The doctor will take into account all risks. Consultation with him is required.

Among the drugs from American and European pharmaceutical manufacturers, the following analogues of Essentiale are especially popular:

  1. Brenziale. This replacement for Essentiale Forte has a composition similar to the original. The main active component is the phospholipid of soybean extract. Brenziale is available for sale in tablet form and solution for injection. The drug is recommended for the treatment different forms hepatitis, intoxication, fatty liver, cirrhosis and hepatic coma. Generic Essentiale Forte costs 150 rubles.
  2. Rezalut PRO. Different from original drug excipients. Compared to Essentiale, Rezalut PRO has a smaller spectrum of action. The medicine is prescribed in the presence of cirrhosis, elevated level cholesterol, hepatitis and liver damage of other origins. The advantage of Rezalut PRO in comparison with other analogues is the possibility of prescribing the medication to children. The drug has contraindications. The doctor will take them into account when prescribing the medicine.
  3. Liver protect. Produced in Serbia. The medicine is made on the basis of soy phospholipid and is a 100% analogue of Essentiale Forte. The generic is intended for the treatment and protection of the liver. Used as prescribed by a doctor. It differs from other analogues in its natural composition and the absence of dyes.

The list of drugs from American and European pharmaceutical manufacturers can be called unlimited. The choice of medication depends on the degree of liver damage and the financial capabilities of the patient.

The liver is sensitive to medications because it is responsible for processing them. Therefore, when selecting an analogue of Essentiale Forte, the doctor and the patient must carefully weigh the pros and cons of each drug.

When considering an alternative to the original, the patient needs to know the differences between the substitutes and Essentiale Forte.

They are as follows:

  • component composition, which often differs in excipients and, as a result, can cause various adverse reactions;
  • cost, which is lower than analogues, which is due to the lack of a patented international name and advertising costs;
  • dosages and treatment regimens, including course duration.

Included Essentiale Forte contains a complex active additives, accelerating the therapeutic effect and increasing the cost of the drug.

The list of diseases for which medications are intended to treat may also differ.

Comparison of prices of Essentiale and analogues

The cost of the original drug is higher than Essentiale analogues of domestic and foreign production.

Below are the prices of medicines in Moscow and St. Petersburg:

Cheap Essentiale analogues Moscow Peter
Minimum in rubles Maximum in rubles Minimum in rubles Maximum in rubles
Rezalut PRO (capsulated form) 507 547 464 535
Livolin Forte (capsules) 426 459 380 444
Hepatosan (capsule form) 370 397
Carsil Forte (capsules) 378 379 328 391
Essliver Forte (capsules) 266 370 276 370

In comparison with the indicated prices, the minimum cost of Essentiale Forte is 698 rubles (30 capsules), and the maximum is 1351 rubles. That's what they ask for for 90 tablets.

For various liver problems, doctors often resort to prescribing Essentiale. It's effective, but not enough expensive product, capable of coping with the task. If you wish, you can choose cheaper analogues instead of Essentiale. There are many medications that have similar effects, but are available at a lower price.

Essentiale: analogues are cheaper (price in rubles)

The cost of this drug is about 650 rubles. This is the reason that many are beginning to think about how to replace Essentiale and are trying to find more affordable drugs. There are many of them:

  • Karsil. Sold in pharmacies for 350 rubles;
  • Essliver Forte. The cost of the drug is only 250 rubles;
  • Rezalut Pro. Its price does not exceed 450 rubles;
  • Phosphogliv. Sold for 500 rubles;
  • Brenziale. One of the cheapest drugs, costing only 150 rubles;
  • Phosphonziale. The price varies between 330-400 rubles;
  • Livolife Forte. Sold in pharmacies for 280 rubles.

Essentiale or Essentiale forte: which is better?

There are several types of drugs that are marketed under the name Essentiale.

When prescribing them, doctors usually do not specify which medication they mean. In this case, only its general name is used.

The medication with the prefix forte is available in the form of capsules that are taken orally. Medicines that do not have such a prefix are ampoules for intravenous administration.

This is the only difference between these means. They have absolutely the same effect on the body, since they contain identical active substance– essential phospholipids.

Phosphogliv or Essentiale: which is better?

Doctors often prescribe Phosphogliv instead of Essentiale. This medication has membrane-stabilizing, hepatoprotective and antiviral effects.

It is produced in the form of capsules and diophilisate, which is administered intramuscularly.

Indications for the use of this medication are as follows:

  • liver cell intoxication;
  • organ tissues are filled with fat cells;
  • cirrhosis;
  • hepatitis;
  • eczema and neurodermatitis;
  • psoriasis.

This medication is not used in the treatment of children under twelve years of age, pregnant women, during lactation, or in case of an allergic reaction to the components of the drug.

In some cases, the following side effects are observed:

  • promotion blood pressure;
  • swelling;
  • gastrointestinal disorders;
  • allergy.

Rezalute or Essentiale

This is an inexpensive analogue of Essentiale, which can also be used in the treatment of liver pathologies. It has a pronounced hepatoprotective effect.

It is produced in the form of capsules, which contain a whole complex of substances that have a beneficial effect on the condition of the organ.

This analogue is used in the following cases:

  • excess fat cells in the liver tissue;
  • toxic organ damage;
  • hepatitis;
  • cirrhosis;
  • elevated cholesterol levels.

There are a number of contraindications to the use of the drug Rezalut:

  • lactation period;
  • children under 12 years of age;
  • increased sensitivity to the components of the product;
  • pregnancy;
  • antiphospholipid syndrome.

The difference between this drug and its analogue is that among side effects as a result of its use, not only dysfunction of organs located in the epigastric region and allergies are noted, but also uterine bleeding.

Karsil or Essentiale

In the treatment of liver diseases, it is allowed to use Karsil instead of the original. This drug is developed for plant based.

It is produced in the form of dragees. Its active ingredient is milk thistle extract.

Karsil is used for various organ problems caused by the following diseases:

  • intoxication;
  • cirrhosis;
  • hepatitis;
  • rehabilitation period after hepatitis;
  • stearosis

The drug is not used in the treatment of children under twelve years of age or in case of hypersensitivity to its components.

There are no significant differences between the substitute and the analogue. These medications have a beneficial effect on the liver and have similar indications for use and contraindications.

In rare cases, both medications may cause an allergic reaction and dysfunction gastrointestinal tract. They resort to replacing the original with Karsil because the cost of the analogue is half as much.

Essliver or Essentiale

Replacement with Essliver is used if it is necessary to restore liver activity. Indications for its use are the following:

  • lipid metabolism is impaired;
  • cirrhosis;
  • psoriasis;
  • hepatitis;
  • intoxication;
  • radiation sickness.

The drug is taken only as prescribed by a doctor. It is contraindicated during pregnancy and in case of individual intolerance to its components. Sometimes, against the background of its use, there are allergic reactions and problems with the gastrointestinal tract. The main advantage of Essliver is its low cost.

Heptral or Essentiale

is a hepatoprotective medication that has cholekinetic, choleteric, antioxidant, detoxifying, and antidepressant effects. It is prescribed in the following cases:

  • damage to the organ by toxins;
  • depressive or withdrawal syndrome;
  • encephalopathy;
  • intrahepatic cholestasis.

Replacing the original with an analogue is allowed only after agreement with the doctor.

Essentiale or Brenziale

The properties of the substitute and analogue are identical. Indications for use of Brenziale are the following:

  • fatty degeneration;
  • liver damage from toxins;
  • organ dysfunction;
  • psoriasis;
  • hepatic coma;
  • hepatitis.

An inexpensive analogue is used when various violations functioning of the organ. Among the side effects, just like Essentiale, allergic reactions and gastrointestinal disorders are sometimes observed.

Fosfontiale or Essentiale

Phosphonciale is a cheap domestic substitute for Essentiale. The active ingredients of this medication lipod and silymara act. Thanks to them, it is possible to perform the following tasks:

  • eliminate inflammatory process in the liver;
  • restore metabolism at the cellular level;
  • remove toxins from the body;
  • activate the process of protein synthesis.

With the help of this drug it is possible to restore metabolic and lipid processes and eliminate the consequences caused by alcohol abuse. It is often used in integrated approach in the treatment of diabetes mellitus.

The medication is contraindicated in hormonal disorders. During lactation and pregnancy, it is used only after prior consultation with a doctor.

Essentiale or Ursosan

One of the popular and effective drugs that has the widest spectrum action is Ursosan. It is often prescribed instead of Essentiale. The main functions of the drug are the following:

  • protecting the organ from negative influences;
  • normalization of liver activity, stimulation of bile outflow, dissolution of stones and creation of a barrier to their formation;
  • elimination of bile stagnation;
  • therapy of hepatitis, cirrhosis and indigestion syndrome;
  • lowering cholesterol levels;
  • strengthening the immune system;
  • preventing the formation of fibrous tissue.

The high effectiveness of the drug is due to the presence of ursodeoxycholic acid in it, which can bind cholesterol and bile acids.

Due to the appearance of these compounds, micelles are formed that help eliminate the toxic effect on the cells of the organ.

The drug is also used in for preventive purposes. With its help, it is possible to reduce the rate of development of colon cancer, remove toxins that appear in people who long time take antibiotics or work in hazardous work.

Among the indications for use of the analogue are:

  • hepatitis, occurring in chronic or acute form;
  • alcoholic organ pathology;
  • underdevelopment of the fetus in pregnant women;
  • cholelithiasis;
  • gallbladder diseases;
  • taking hormonal contraceptives.

Contraindications to the use of the drug are:

  • individual intolerance to components;
  • acute infectious diseases;
  • gallbladder not performing its functions;
  • liver or kidney failure;
  • period of pregnancy and lactation.

Unlike Essentiale, Ursosan can cause significantly more side effects. Often, nausea and vomiting, constipation, painful sensations in the lumbar region, allergies, diarrhea and psoriasis may worsen. This remedy should be used only as prescribed by a doctor. It is impossible to independently determine the dosage and duration of therapy.

There are many inexpensive ones, but effective analogues Essentiale. Each of them has a number of both advantages and disadvantages. Replacement can be made only after coordinating therapy with a doctor. Without consulting a specialist, such manipulations are strictly prohibited.

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Essentiale Forte N belongs to a group of pharmacological drugs that are used to restore the functional activity of the liver. The drug quickly and effectively eliminates damage that occurs due to cirrhosis, fatty degeneration, various forms hepatitis. Due to its ability to restore liver cells (hepatocytes), Essentiale Forte N is used not only for the treatment of pathologies, but also for their prevention. To avoid complications after taking the drug, you must adhere to the dosages prescribed by the doctor, and also not exceed the duration of the course of treatment.

Essentiale Forte N helps quickly restore liver cells

Characteristic features of hepatoprotectors

The therapeutic effect of Essentiale Forte N is based on the properties of the phospholipid compounds included in its composition. Organic substances have the ability to normalize metabolic processes occurring in hepatocytes. Phospholipids also:

  • restore the structure of liver cells;
  • normalize the functioning of hepatocytes.

The main biological filter of the human body is subjected to significant stress. It neutralizes toxic compounds that have entered the systemic bloodstream, converting them into harmless compounds. But under the influence of provoking factors, the liver itself undergoes destructive changes. Hepatoprotectors, which include Essentiale Forte N and its analogues, help to reverse the process and improve the functioning of cells:

  • Heptor;
  • Rezalut Pro.

The active ingredients of these drugs eliminate not only the symptoms of the disease, but also the cause of its development. They prevent the degeneration of hepatocytes into rough connective tissue, unable to take part in metabolic processes. The above drugs are not structural analogues, that is, their composition is not identical. But they all have the ability to quickly and effectively restore liver function.

Composition and release forms

The manufacturer produces Essentiale Forte in the form of a solution for parenteral administration and capsules for oral administration. The main active ingredient of the drug is phospholipids obtained from the processing of soybeans. The primary packaging of the solution is 5 ml dark glass ampoules placed in blisters with contour cells. To stabilize this dosage form The following auxiliary components were used:

  • sodium chloride;
  • sodium hydroxide;
  • benzyl alcohol;
  • deoxycholic acid.

Characteristic yellowish color The solution is given the B vitamin riboflavin. The liquid form of Essentiale Forte is intended for intravenous administration only and does not combine well with other injectable drugs. The solution decomposes quickly at room temperature, so it should be stored in the side wall of the refrigerator. Secondary packaging of the drug is a cardboard box with an annotation inserted inside.

The solid form of the drug is represented by brown, oblong, opaque capsules filled with thick dark contents. They are placed in contour blisters made of metallized foil, 10 pieces each. In addition to essential phospholipids, Essentiale Forte N includes the following ingredients:

  • gelatin;
  • iron oxide;
  • ethanol;
  • castor oil;
  • solid fats;
  • ethyl vanillin;
  • alpha tocopherol.

Auxiliary components are intended for the formation of capsules. The protective shell prevents aggressive gastric juice inhibit phospholipids. They freely penetrate into small intestine and begin to gradually release from the shell. Additional ingredients also enhance the therapeutic properties of the active substance, facilitating rapid absorption into the systemic circulation, from where they enter the liver. Essentiale Forte capsules should also be stored in a cool place, protected from sunlight.

Advice: “The manufacturer produces Essentiale Forte capsules in secondary packaging No. 30 and No. 100. If you purchase a large pack of the drug for a long course of treatment, you can save significantly.”

Therapeutic effect of hepatoprotectors

Phospholipids Essentiale Forte N are similar in structure to phospholipids that are found in the liver. Thanks to this, the active ingredients of the drug are easily integrated into hepatocytes and begin to actively function. Essentiale Forte N phospholipids are characterized by a high concentration of polyunsaturated fatty acids, especially linoleic. These compounds, after penetrating the liver, become part of hepatocytes, including intercellular membranes. Fatty acids:

  • accelerate tissue regeneration;
  • promote active division of liver cells.

Phospholipids of Essentiale Forte and its analogues combine the hydrophobic and hydrophilic properties of the molecule due to the presence of different sections. This provides a variety of functions they perform by stimulating the permeability of intercellular membranes. Ion exchange on their surface accelerates, and the deficiency of nutrients and biologically active substances is gradually compensated. Phospholipids of hepatoprotectors normalize intracellular respiration by binding mitochondrial enzymes.

In a person with normal condition health, polyunsaturated fatty acids are synthesized as needed. As diseases develop, the structure of intercellular membranes is disrupted and the functioning of enzymatic compounds is disrupted. All this leads to a distortion of the processes of phospholipid formation, and cell membranes cease to perform their functions. A course of taking Essentiale Forte N replenishes the supply of substances necessary for the liver and prevents the development of irreversible consequences.

Analogs

Essentiale Forte N is an expensive medicine. Since the drug is intended for long-term course therapy, the patient will need to purchase several large packages. Gastroenterologists often recommend capsules and an injection solution to prevent liver dysfunction. This is especially true for people with chronic diseases who are forced to take large amounts of medications every day. It is not surprising that there is a forced need to choose a substitute for Essentiale Forte. In this case, the following conditions must be met:

  • the analogue should be cheaper;
  • the therapeutic effectiveness of the substitute cannot be lower than that of the original.

Despite the wide range of hepatoprotectors in pharmacies, choosing an inexpensive analogue equivalent to Essentiale Forte is quite problematic. Cheap drugs usually contain only medicinal herbs which have a beneficial effect on the liver. And if capsules or tablets contain essential phospholipids, then their concentration is significantly lower than in the original. To choose a worthy substitute for Essentiale Forte, you should compare the drugs.

The domestic drug Essliver Forte is available in capsules and contains phospholipids. Perhaps this is the closest inexpensive analogue of Essentiale Forte N in terms of therapeutic effect. Manufacturers have supplemented the composition of the drug with a complex of B vitamins, nicotinamide and tocopherol acetate.

Essliver Forte has a hepatoprotective effect similar to Essentiale Forte

Essliver Forte normalizes oxidative phosphorylation and increases the activity of liver enzymes. Phospholipids are embedded in biological membranes, eliminating damage to hepatocytes. Vitamins are responsible for metabolism:

  • proteins;
  • fats;
  • lipids.

Vitamin E has an antioxidant effect, which provides reliable protection of hepatocytes from fat cross-oxidation.

The disadvantages of this drug include a longer course of treatment than Essentiale Forte N. The presence in the composition large quantity vitamins limits the range of patients for whom essential phospholipids are indicated. Some people have individual sensitivity to these biologically active substances. In others, the liver cells are so damaged that the use of additional chemical compounds does not bring benefit, but harm.

Recommendation: “Gastroenterologists recommend taking Essliver Forte to patients who cannot afford to purchase Essentiale Forte. Due to the different quantitative content of phospholipids, you should consult a doctor to adjust daily and single dosages, as well as the duration of treatment.”

Ursosan belongs to the group of hepatoprotectors that are used to treat pathologies of the biliary tract and restore the functional activity of the liver. The drug has choleretic, antilithogenic, immunomodulatory and antifibrotic effects. Unlike Essentiale Forte, Ursosan is indicated for the following diseases:

  • sclerosing cholangitis;
  • biliary dyskinesia;
  • biliary reflux gastritis;
  • biliary esophagitis;
  • dyspeptic syndrome.

Ursosan contains no essential phospholipids. Its therapeutic effectiveness is based on the only active substance- ursodeoxycholic acid. Therefore, this drug cannot be considered a structural analogue of Essentiale Forte N. It is used more for dissolving stones in gallbladder. The medicine cleanses bile ducts and the liver from toxins and toxic compounds, but its ability to restore hepatocytes is much lower. Only a gastroenterologist can choose which is better - Ursosan or Essentiale Forte. It takes into account the results of laboratory and instrumental studies, and also general condition patient's health.

Ursosan, like Essentiale Forte, is used to treat liver diseases

Rezalut Pro

Another structural analogue of Essentiale Forte is Rezalut Pro, produced in the form of capsules with a transparent shell. Hepatoprotector restores damaged liver cells, improves them protective functions. The drug contains the same amount of phospholipids as Essentiale Forte, but they differ slightly in the quality of polyunsaturated fatty acids. Manufacturers included Rezalut Pro tocopherol acetate, which prevents the destruction of hepatocytes. The drug is used for the following pathologies:

  • fatty liver of various ethologies, including alcoholic;
  • cirrhosis;
  • toxic or drug damage hepatocytes;
  • hepatitis of various origins;
  • hypercholesterolemia.

Unlike Essentiale Forte, Rezalut Pro is used to treat neurodermatitis. The drug is recommended for use by patients for preventive purposes when there is a risk of exacerbation cholelithiasis. This medicine is not cheap, but its price is still lower than Essentiale Forte.

Karsil

Karsil is a time-tested remedy for restoring the functional activity of the liver. The undoubted advantage of the drug is its natural composition with a large number of different phospholipids. contains the fruits of milk thistle, infusions of which are often found in recipes traditional healers. The drug has a multifaceted therapeutic effect on the main biological filter of the human body:

  • neutralizes toxic compounds;
  • relieves damage to the intercellular membranes of liver cells;
  • normalizes metabolic processes in hepatocytes.

After viral or viral pathogens enter the human body, bacterial infections the liver is subject to significant stress. It cleanses the blood of enterotoxins, metabolizes pharmacological preparations. Doctors recommend during the rehabilitation period course treatment Karsil, which has a mild restorative effect.

The liver is one of the vital organs, the dysfunction of which leads to the development of many serious illnesses. To prevent and treat pathological processes in the liver, it is necessary to take drugs aimed at restoring cellular tissue, as well as general work organ. For medicines that have predominantly positive reviews, include Essentiale Forte N and drug analogues.

Essentiale Forte

The hepatoprotective drug Essentiale Forte N is intended for the treatment of liver diseases.

The medicine is produced in capsules containing a plant component - extract (phospholipids) of soybeans, which contains choline, which has an effect on the liver.

The list of indications includes pathological processes, occurring in the liver:

  • cirrhosis;
  • chronic and alcoholic hepatitis;
  • toxicosis in pregnant women;
  • liver intoxication;
  • fatty degeneration of the organ;
  • impaired functionality (secondary form in somatic diseases);
  • radiation damage;
  • cholelithiasis;
  • psoriatic inflammation.

When used therapeutically for the liver, Essentiale Forte is contraindicated in childhood up to twelve years and in case of intolerance to the medicinal composition.

In individual cases, medication may be the cause side effect: gastrointestinal upset or allergic reaction.

The Russian drug has an average cost of 650 rubles

Analogs

Drug treatment of the liver should be carried out only in accordance with all the instructions of the doctor observing the patient. When replacing Essentiale, analogues should be purchased only with the consent of a specialist.

Reviews about the drug confirm its effectiveness therapeutic effect. Also, the medication rarely causes an adverse reaction and has a minimum of contraindications. Based on this information, a substitute for the original is most often selected due to the high price of the capsules.

In a modern pharmacy, buy more cheap analogue Essentiale Forte for liver therapy can be taken without any particular difficulties, and besides, drugs in this group are not prescription drugs.

Karsil

Can be used to eliminate liver pathologies cheap substitute Essentiale Forte – Karsil.

The medicine is developed on a plant basis. The analogue, produced by the manufacturer in the form of dragees, contains the active substance - extract (dry) of the fruits of spotted milk thistle.

  • hepatitis;
  • radioactive intoxication;
  • steatosis;
  • rehabilitation period after hepatitis;
  • cirrhosis;
  • drug and alcohol intoxication.

An analogue of Essentiale Forte is not recommended for use in children under 12 years of age if they are sensitive to the components of the drug.

There are no significant differences in pharmacology between the drugs Essentiale and Karsil. Both medications have therapeutic effect on the liver, have similar indications and contraindications. Just like the original, the analogue rarely causes adverse reaction in the form of allergies or temporary gastrointestinal dysfunction.

Replacing Essentiale Forte affects only the price and possibly individual reaction body. Karsil costs almost half as much, 350 – 400 rubles.

Essliver Forte

An inexpensive analogue of Essentiale Forte, Essliver Forte, is recommended by experts to restore liver function.

The composition of the capsules (release form) includes the active ingredients:

  • phospholipids essentiale;
  • alpha tocopherol acetate;
  • B vitamins;
  • nicotinamide

Indications for therapy with Essliver:

  • psoriasis;
  • impaired lipid metabolism in the liver;
  • hepatic degeneration of fatty type;
  • hepatitis or cirrhosis;
  • intoxication damage to the organ;
  • radiation sickness.

The medicine should not be prescribed or taken (without the knowledge of the doctor) if you are allergic to the composition and during lactation/pregnancy.

A cheap substitute for Essentiale can cause allergies or problems with the gastrointestinal tract.

The advantage of Essliver is the price. An analogue costs about 250 rubles.

Rezalut Pro

The drug Rezalut Pro is a cheap analogue of Essentiale Forte N, which has a hepatoprotective effect on the liver.

The analog release form is capsule. The medicine contains a complex of substances that have a positive effect on the liver:

  • soy lecithin phospholipids;
  • glycerol;
  • refined soybean oil;
  • triglycerides;
  • tocopherol

An inexpensive analogue of Essentiale Forte is prescribed for the treatment of liver pathologies:

  • excess fat cells on organ tissues;
  • damage by toxins;
  • hepatitis;
  • hypercholesterolemia;
  • cirrhosis.

Contraindications to the drug:

  • antiphospholipid syndrome;
  • breastfeeding;
  • children under 12 years of age;
  • sensitivity to the substances in the composition;
  • bearing a fetus (women).

A cheap substitute for the original drug, unlike Essentiale and other analogues, can provoke not only dysfunction of the epigastric organs and an allergic reaction, but also bleeding in women.

The drug has an average cost in pharmacies - 450 rubles.

Phosphogliv

When selecting analogues of Essentiale Forte N, doctors advise patients to use a combination drug - Phosphogliv. The drug has hepatoprotective, membrane-stabilizing and antiviral properties.

The Russian analogue of Essentiale Forte is produced not only in capsule form, but also in the form of a lyophilisate used for dilution medicinal solution (intramuscular injections). The active ingredients are glycyrrhizinate and soy phospholipids.

Indications for analogue:

  • intoxication cellular damage to the liver;
  • filling liver tissue fat cells;
  • cirrhotic destruction of the cellular structure of the liver;
  • viral and other forms of hepatitis;
  • neurodermatitis or eczema (lyophilisate);
  • psoriatic inflammation.

Just like other cheap analogues of Essentiale Forte, Phosphogliv is contraindicated in children. age category less than 12 years old, pregnant and lactating women, patients with a tendency to be allergic to the composition. In addition to the main contraindications injection form The drug is not prescribed to patients with arterial and portal hypertension.

Adverse reaction to a cheaper analogue:

  • in capsules - increased pressure in the arteries, peripheral edema, dysfunction of the stomach and intestines, manifestations of allergies;
  • lyophilisate – allergic rashes, blood pressure surges and swelling.

Despite the fact that other domestic cheap analogues of Phosphogliv have a lower cost, it is prescribed quite often as a replacement for the original product.

The price for Phosphogliv is from 500 rubles.

Brenziale

Comparing Brenziale and other cheap substitutes for the original medicine, experts note that Essentiale and this drug have identical properties.

Brenziale also contains phospholipids from soybean extract. However, in addition to capsules, the substitute has a release form - an injection solution.

Indications:

  • hepatitis;
  • dystrophy (fatty);
  • hepatic coma;
  • intoxication;
  • dysfunction;
  • radiation sickness;
  • cirrhosis;
  • psoriatic disease.

All indications for the use of a cheap analogue relate to liver dysfunction.

Contraindications are the child's age less than 12 years and sensitivity to the components.

The side effect causes signs of allergies and gastrointestinal dysfunction.

Cost – from 150 rubles.

Conclusion

If it is necessary to replace Essentiale with cheaper generics, you must first consult with the doctor who individually monitors the patient. If the patient buys cheap drug independently, then he must study the instructions for medicine to avoid exacerbation of pathology or adverse reactions.

Instructions for use. Contraindications and release form.

Instructions
By medical use drug
Essentiale



Dosage form:
Capsules.

Compound:
1 capsule contains:active ingredient: phospholipids from soybeans containing 76% (3-sn-phosphatidyl)-choline (synonyms: EPL, essential phospholipids) – 300 mg;
auxiliary ingredients: solid fat - 57,000 mg, soybean oil - 36,000 mg, hydrogenated castor oil - 1,600 mg, ethanol 96% - 8,100 mg, ethyl vanillin - 1,500 mg, 4-methoxyacetophenone - 0.800 mg, α-tocopherol - 0.750 mg.
Capsule composition: gelatin – 67.945 mg, purified water – 11.495 mg, titanium dioxide (E 171) – 0.830 mg, yellow iron oxide dye (E 172) – 2.075 mg, black iron oxide dye (E 172) – 0.332 mg, iron dye red oxide (E 172) – 0.198 mg, sodium lauryl sulfate – 0.125 mg.

Description
Hard gelatin opaque capsules No. 1 brown, containing an oily paste-like mass of yellowish-brown color.

Pharmacotherapeutic group:
Hepatoprotective agent
ATX code: A05C

Pharmacological properties
Pharmacodynamics

Essential phospholipids are the main elements of the structure of the cell membrane and cellular organelles. In liver diseases, there is always damage to the membranes of liver cells and their organelles, which leads to disruptions in the activity of associated enzymes and receptor systems, deterioration in the functional activity of liver cells and a decrease in the ability to regenerate.
The phospholipids included in the preparation Essentiale® forte N correspond in their chemical structure endogenous phospholipids, but are superior to endogenous phospholipids in activity due to their higher content of polyunsaturated (essential) fatty acids. The integration of these high-energy molecules into damaged areas of hepatocyte cell membranes restores the integrity of liver cells and promotes their regeneration. The cis-double bonds of their polyunsaturated fatty acids prevent the parallel arrangement of hydrocarbon chains in the phospholipids of cell membranes; the phospholipid structure of the cell membranes of hepatocytes is “loosened,” which increases their fluidity and elasticity and improves metabolism. The resulting functional blocks increase the activity of enzymes fixed on the membranes and contribute to the normal, physiological pathway of the most important metabolic processes.
Phospholipids, which are part of the drug Essentiale® forte, regulate the metabolism of lipoproteins, transferring neutral fats and cholesterol to sites of oxidation, mainly by increasing the ability of lipoproteins high density bind to cholesterol.
Thus, there is a normalizing effect on the metabolism of lipids and proteins; on the detoxification function of the liver; to restore and preserve the cellular structure of the liver and phospholipid-dependent enzyme systems; which ultimately prevents the formation connective tissue in the liver and promotes natural recovery liver cells.
With the excretion of phospholipids into the bile, the lithogenic index decreases and the bile is stabilized.

Pharmacokinetics
More than 90% of phospholipids taken orally are absorbed in the small intestine. Most of them are cleaved by phospholipase A to 1-acyl-lysophosphatidylcholine, 50% of which is immediately reverse acetylated into polyunsaturated phosphatidylcholine during the absorption process in the intestinal mucosa. This polyunsaturated phosphatidylcholine enters the bloodstream through the lymph and from there, mainly bound to high-density lipoproteins, enters the liver.
Pharmacokinetic studies in humans were performed using radiolabeled dilinoleyl phosphatidylcholine (3H and 14C). The choline moiety was labeled with 3H, and the linoleic acid residue had 14C as its label.
The maximum concentration of 3H is reached 6-24 hours after administration and is 19.9% ​​of the prescribed dose. The half-life of the choline component is 66 hours.
The maximum concentration of 14C is reached 4-12 hours after administration and is up to 27.9% of the prescribed dose. The half-life of this component is 32 hours. In feces, 2% of the administered dose of 3H and 4.5% of the administered dose of 14C are found, in urine - 6% of 3H and only a minimal amount of 14C.
Both isotopes are more than 90% absorbed in the intestine.

Indications for use
Chronic hepatitis, liver cirrhosis, fatty liver of various etiologies, toxic liver damage, alcoholic hepatitis, liver dysfunction in other somatic diseases.
Toxicosis of pregnancy.
Prevention of recurrence of gallstone formation.
Psoriasis (as an adjuvant therapy).
Radiation syndrome.

Contraindications
Known hypersensitivity to phosphatidylcholine or other excipients of the drug.
Children under 12 years of age (lack of sufficient evidence base).

Directions for use and doses
Inside. Capsules should be swallowed whole with plenty of water (approximately 1 glass).
For adolescents over 12 years of age and weighing more than 43 kg, as well as for adults, Essentiale® forte N is recommended to take 2 capsules - 3 times a day with meals.
As a rule, the duration of use is not limited.

Side effect
Essentiale forte N is usually well tolerated by patients.
To assess the frequency of side effects, the following definitions are used: very often (> 1/10), often (> 1/100 -< 1/10), не часто (> 1/1000 - < 1/100), редко (> 1/10000 - < 1/1000), очень редко (< 1/10000), неизвестная частота (по имеющимся данным не возможно установить частоту возникновения).
From the gastrointestinal tract
In some cases, taking Essentiale® forte N may cause stomach discomfort, soft stools or diarrhea.
Allergic reactions
In very rare cases, allergic skin reactions (rash, exanthema, urticaria, itching) are possible.

Release form
Capsules 300 mg.
10 capsules in a blister made of PVC and aluminum foil. 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14 or 15 blisters along with instructions for use in a cardboard box.
10 capsules in a blister made of PVC and aluminum foil. 5 blisters per cardboard box. 3 cardboard packs along with instructions for use in a cardboard box.
12 capsules per blister made of PVC and aluminum foil. 3, 4, 5, 6, 7, 8, 9, 10 or 11 blisters along with instructions for use in a cardboard box.
15 capsules in a blister made of PVC and aluminum foil. 2, 3, 4, 5, 6, 7, 8 or 10 blisters along with instructions for use in a cardboard box.

Best before date
3 years.
Do not use the drug after the expiration date indicated on the package.

Storage conditions
Store at a temperature not exceeding 21 °C.
Keep out of the reach of children.

Conditions for dispensing from pharmacies
Over the counter.

Manufacturer
A. Nattermann & Hsieh. GmbH., Germany
Nattermannallee 1, D-50829, Cologne, Germany.