Treatment of acute and chronic infections genitourinary system is carried out using the drug Furagin - the instructions for use contain all the necessary information about its mechanism of action and dosage for adult patients. Can be used topically as an antibacterial disinfectant to treat burns or purulent wounds.
The antibacterial drug Furagin belongs to a line of synthetic antimicrobial agents. Mechanism of action of the main active substance is based on inhibition of the reproduction processes of gram-negative bacteria, suppression of their vital processes. Due to this bacteriostatic effect, relief of the patient’s condition is achieved (until the complete death of the microorganisms that provoked the inflammation).
Active active substance The drug Furagin - furazidin - is a derivative of nitrofuran. The product is produced in three main forms - tablets, capsules and powder. The capsule form contains 25 mg of the main substance and the following excipients:
Furagin capsules are called Furagin-Aktifur, packaged in sealed blisters of 10 pieces; one box can contain from 30 to 150 capsules and instructions for use medicine. Furagin, produced in powder form, has another name - Furasol. Packaged in sachets of 1 g, the content of furazidine in each sachet is 100 mg. Excipient serves as sodium chloride. The composition of the tablet form of the drug is presented in the table below:
How the antimicrobial drug used for the treatment and prevention of infections, Furagin, works - the instructions for use describe in detail, its main features are given pharmacological properties. The main active ingredient - furazidin - is active against gram-negative microorganisms (staphylococci and streptococci) and gram-positive microorganisms - salmonella, shigella, coli. Therapy with the drug is ineffective against the following infectious agents:
Absorption (assimilation) of the active substance occurs in small intestine by passive suction method. This is how furazidin enters the lymph, preventing the spread of infection through the lymphatic system. Metabolized by the liver 4-8 hours after absorption and excreted in the urine. According to the instructions for use, the main effect is achieved due to the high bacteriostatic concentration of furazidin in the urine, therefore it is actively used in urology.
According to the instructions for use, Furagin is not a systemic antibiotic. It has an antibacterial effect on the organs of the urinary system - bladder, kidneys, urethra. A particularly high concentration of furagin in urine makes it effective means in the fight against urinary tract infections. Is an antibacterial drug local action(helps with purulent wounds and various gynecological infections), and not an antibiotic.
The main indications for taking Furagin, according to the instructions, are acute and chronic recurrent infections urinary tract, the pathogens of which are sensitive to the active ingredient of the drug. These include:
Possible local use as a solution for burns and purulent wounds, in the treatment of keratitis, conjunctivitis, vulvovaginitis. As a preventative antiseptic Furagin solution is used during diagnostic and surgical interventions in urology, for washing with peritonitis and pleural empyema.
According to the instructions for use, the dosage regimen and duration of drug therapy are determined by the attending physician in accordance with the diagnosis and severity of the patient’s condition:
The instructions for use recommend using the drug with caution in case of illness. nervous system, dysfunction and other diseases of the kidneys and liver. Furagin may cause individual intolerance and allergic reactions Therefore, in some cases, according to the decision of the attending physician, therapy is accompanied by the use of antihistamines. To prevent the appearance side effects recommended drinking plenty of fluids. In some cases, B vitamins are prescribed to prevent neuritis.
During pregnancy, the female urinary system is weakened and therefore especially susceptible to inflammatory and infectious diseases. If symptoms of inflammation appear - pain when urinating and frequent urges if your temperature rises, you should immediately consult a doctor. Advanced inflammations are difficult to treat and contribute to the development of such dangerous conditions, like gestosis, become a threat to both the fetus and the life of its mother. Therefore, a doctor may decide to have a pregnant woman undergo a course of treatment with Furagin.
According to the decision of the attending physician, Furagin is prescribed for children over 1 year of age if there are appropriate indications. Therapy should be carried out with caution, with strict adherence to the dosage and dosage regimen. The instructions for use contain instructions for calculating the maximum daily dosage for a child. The recommended dose of the drug is calculated based on body weight - 5-7 mg/kg/day. If side effects occur, treatment should be stopped immediately and the child urgently is shown to the doctor. Topical use is not recommended for infants under 6 months of age.
Simultaneous use with ristomycin, chloramphenicol, sulfonamides, according to the instructions for use, increases the risk of hematotoxicosis. Concomitant use of other nitrofuran derivatives, as well as urine oxidizing agents, such as ascorbic acid or potassium chloride, should be avoided. Ethanol can increase the severity of side effects and reduce the effect of the main active substance.
When drinking alcohol during the course of treatment with the drug, a number of unpleasant side effects associated with the activity of the central and peripheral nervous system may occur. Avoiding drinks containing ethanol, will help you avoid:
Instructions for use describe the side effects that may occur while taking Furagin. They may be caused by an incorrectly calculated dosage or individual reaction. These include:
If the treatment regimen is incorrectly calculated, an overdose of the drug may occur. According to the instructions for use, it is accompanied the following symptoms and conditions - neurotoxic reactions, polyneuritis, liver dysfunction, acute toxic hepatitis. Treatment begins with the abolition of Furagin, heavy drinking is prescribed, symptomatic therapy, B vitamins. There is no specific antidote.
A course of treatment with the drug can be prescribed by a doctor when the expected benefit from taking it exceeds possible harm. Therefore, in some cases (for example, during pregnancy), it can be passed drug therapy, but with caution, under the supervision of specialists. The manufacturer states in the instructions for use that Furagin is contraindicated for:
The drug is sold in pharmacies and is available without a doctor's prescription. Stored out of the reach of children, shelf life is 3 years from the date of issue. It is not allowed to take an expired drug.
The most common analogue of Furagin is the imported drug Furadonin. The active substance of Furadonin - nitrofurantoin - has a pronounced antimicrobial effect. Another popular substitute with a similar active ingredient (furazidine) is Furamag. A doctor can prescribe Furagin or Furamag based on clinical picture disease and individual characteristics of the patient. In case of adverse reactions one drug can be replaced by another.
In addition to these drugs, it is possible to replace them with:
Furagin is sold in pharmacies without a doctor's prescription. The drug can be ordered through the online store and delivered to your home (the price will then be lower than usual). With a price range of different shapes release can be found. looking at the table below:
Furagin is a synthetic antibacterial drug, possessing bactericidal effect against a large number of microorganisms. It is completely absorbed in the intestinal lumen and transported through the bloodstream to the kidneys. It is excreted unchanged in the urine, which makes it possible to create a high concentration of Furagin in the urine. Has a damaging effect on components microbial cell, which leads to her death. Used to treat diseases of the urinary and reproductive systems. It does not accumulate in the body and does not lead to the development of complications typical for antibiotic therapy.
In addition, Furagin is distinguished by the lowest concentration required to achieve positive result. The greatest activity of the drug is observed at acidic urine pH.
Bacterial activity:
The duration of treatment in all cases is no more than a week.
While taking Furagin, false positive reactions to the concentration of glucose in the urine are observed.
Long-term use of the drug should be accompanied by regular monitoring of liver and kidney function, as well as the percentage of leukocytes.
The drug does not have an inhibitory effect on the nervous system and is approved for use by persons whose activities are related to reaction speed and control complex mechanisms, including any vehicles.
Shelf life - no more than 4 years.
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* Instructions for medical use to the drug Furagin was published in free translation. THERE ARE CONTRAINDICATIONS. BEFORE USE, YOU MUST CONSULT WITH A SPECIALIST
Furagin - antimicrobial agent, a derivative of nitrofuran. Active against gram-positive and gram-negative microbes, pathogenic strains of Staphylococcus spp. and other microorganisms resistant to antibiotics.
Effective against gram-positive cocci (Staphylococcus spp., Streptococcus spp.), gram-negative rods (Escherichia spp., Salmonella spp., Shigella spp., Proteus spp., Klebsiella spp., Enterobacter spp.), protozoa (Lamblia intestinalis).
The drug is based on the active substance – furazidin, which has an aromatic nitro group in its structure. The active substance inhibits the formation of bacteria nucleic acids, preventing the proliferation of microorganisms, destroying their outer shells and cytoplasmic membranes.
Furagin for the kidneys, when used internally, reaches the urinary system, disinfecting the kidneys, ureters, bladder and urethra. Some people mistakenly assume that it is an antibiotic. However, Furagin is not an antibiotic, since it is not capable of having a system-wide effect. It does not belong to the group of antibiotics, emphasizing its local antibacterial effect on the genitourinary system.
Absorption of the drug occurs first in the intestine, then the active substance enters the lymphatic system, blocking this route of infection. After several hours, the active substance enters the urine, killing bacteria in urinary system, after which the drug is completely removed from the body.
What does Furagin help with? The drug is prescribed in the following cases:
Tablets and capsules are taken after meals with plenty of water.
Adults are prescribed an average of 50-100 mg 3 times a day, a course of 7-14 days, after which a break of 10-15 days is required.
If necessary, the course can be repeated after a break.
Children take:
The course of treatment lasts no more than 8 days. If you need to repeat therapy, the instructions for use allow you to do this after a 2-week break.
As a preventative measure, the drug is prescribed one tablet (50 mg) once a day at night. The duration of prophylaxis can be up to 2 weeks.
Prescribing Furagin for the treatment of the urinary tract is possible only in the absence of contraindications:
Furagin colors urine dark yellow or brown. To reduce side effects It is recommended to take B vitamins, antihistamines and use large number liquids.
Manifested by headaches, depression, dizziness, psychosis, peripheral polyneuritis, nausea, impaired liver function (rarely).
In persons with congenital deficiency the enzyme glucose-6-phosphate dehydrogenase, with an overdose of Furagin, aplastic or megaloblastic anemia is possible. Severe allergic reactions are possible (bronchospasm, angioedema, urticaria).
Prescribing Furagin may cause the following side effects:
In the described cases, it is necessary to reduce the dosage of the drug or discontinue it. Side effects are reduced by drinking plenty of fluids during treatment.
The use of Furagin during pregnancy and lactation is contraindicated. In case of urgent need, the use of the drug is possible only after stopping breastfeeding until it is completely eliminated from the body.
If necessary, replace Furagin with an analogue, list of similar drugs:
When choosing analogues, it is important to understand that the instructions for use of Furagin, the price and reviews do not apply to drugs with similar effects. It is important to consult a doctor and not change the drug yourself.
You can buy Furagin in pharmacies from 210 rubles. The price of tablets in Belarus varies from 7.5 to 11 rubles.
Furamag product contains potassium furazidin and basic magnesium carbonate. The differences between Furamag and Furagin mainly lie in the fact that the first drug has higher bioavailability. In the blood maximum concentration its active component lasts longer.
Accordingly, if we consider which is better - Furamag or Furagin - we can unequivocally answer that the bacteriostatic effect of the first remedy is higher.
The drug affects many gram-positive And gram-negative microorganisms. His healing effect due to the fact that the drug belongs to nitrofurans and includes a molecule that can bind to biologically active substances in microbial cells that are capable of carrying a hydrogen molecule. This prevents further activity of the microbial cell.
To achieve a positive result, the active substance of the drug in a small concentration is sufficient.
The drug is absorbed in the intestine through passive diffusion. When taken orally it has disinfecting effect on the kidneys, urethra, bladder. The drug is excreted by the kidneys.
On forums you can often come across the question, Furagin is antibiotic or not? This medicine is antibacterial And antimicrobial preparation. Unlike many antibiotics he doesn't have systemic action. The drug is intended for topical use and cannot in any way be classified as systemic .
Indications for use of Furagin:
Specialists can prescribe Furagin for, including after operations.
In addition, in pharmacies you can find such a remedy as Furagin Lect. He also has antimicrobial broad spectrum action.
Indications for use Furagina Lect:
You cannot use Furagin tablets for cystitis and others genitourinary system with negative reaction body for the drug and .
Besides, this remedy contraindicated in the case of:
The following side effects are possible when taking tablets:
In addition, there may be malaise , increased body temperature, chills .
For those who have been prescribed Furagin tablets, the instructions for use indicate that they should be taken with meals. This should be done in the following dosages:
The duration of therapy does not depend on what Furagin is used in each specific case. It should be a maximum of 7-10 days. If necessary, treatment cystitis tablets, as well as other inflammatory And infectious diseases genitourinary system can be extended after 10-15 days.
Instructions for use Furagin Lect informs that the product is also intended for internal use. Adults should take 50-100 mg, children over 3 years old should take 25-50 mg. The medicine in the prescribed dosage is taken 3 times daily. Therapy is designed for 7-10 days. If the course needs to be repeated, you need to take a break for 10-15 days.
For prevention, take 50 mg of the drug once half an hour before the procedure.
In addition, the drug can be used externally 2-3 times every day to wash wounds or wet bandages. The product is also used as a mouth and throat rinse 2-3 times daily.
Overdose symptoms:
If the drug is used in excess doses, it is prescribed gastric lavage , and also medicinal elimination of overdose symptoms. In difficult situations it is indicated.
A decrease in the effectiveness of the drug and an increase in the concentration of its active substance in is observed when combined with drugs perdlidixic acid , as well as medications that increase the level of uric acid in the urine.
Interaction with drugs that reduce the acidity of gastric juice and include magnesium trilixad , can lead to a marked decrease in the degree of absorption of the drug.
This medicine is sold by prescription. Only a doctor can determine what Furagin tablets will be effective for in each specific case and according to what regimen they should be taken.
The medicine should be kept in a dry place out of reach of sunlight. The temperature should be up to 30°C. Keep away from children.
Five years.
Level 4 ATX code matches:
Such analogues of Furagin are known as and. These medications cannot be replaced at your own discretion, without consulting your doctor.
Which is better: Furamag or Furagin?
Often on medical forums people ask about Furagin analogues. Most often in in this case recommend Furamag . This product contains furazidine potassium And basic .
Differences Furamaga and Furagin mainly consist in the fact that the first drug has higher bioavailability. And in the blood the maximum concentration of its active component remains longer. Accordingly, for those who are interested in what is better - Furamag or Furagin - we can answer unequivocally that bacteriostatic effect the first remedy is higher.
Children of all ages often suffer from infections urinary system. However, often an incompletely cured disease can return. This can be avoided if you take appropriate medicines according to the instructions. In this case, experts very often recommend. However, if for one reason or another they are not suitable for use, Furagin is prescribed to children. Unlike many antibiotics it is not addictive.
In addition, this remedy combines well with many other medications. For children who tolerate it well, the drug is prescribed not only for treatment inflammatory And infectious diseases , but also for preventive purposes.
However, it should not be given to patients under 1 month of age, especially if the baby is not even a week old. In addition, the drug is prescribed with caution for children under 3 years of age.
The dosage of Furagin for children can be from 5 to 7 mg per 1 kg of weight. For babies up to one year old, the tablets are ground into powder, which is mixed with a certain amount of liquid (milk, formula). If long-term therapy is planned, the specialist reduces the dosage for children to 1-2 mg per 1 kg of weight.
Use Furagin for pregnancy contraindicated. If taking pills is necessary during lactation , breastfeeding is stopped and continued only after the drug is completely eliminated from the body.
And also prostatitis. They cause a lot of problems and inconveniences, and also affect the quality of life.
They should not be started, as they tend to take on a more severe form. When the first symptoms of these diseases appear, you should immediately contact a personal specialist.
At his discretion, he will prescribe medications that will restore health to the affected organs. One of these drugs is, instructions for use of which are outlined below in this article.
You should always inform your doctor if you are taking other medications.
Significant inhibition of the excretion of the active component of the drug in urine may increase the risk of toxicity. This applies to combining Furagin with Probenecid and Sulfinpyrazone.
This can also be observed when using certain medications that acidify urine ( ascorbic acid, calcium chloride). When drugs such as antacids containing calcium or magnesium, carbonic anhydrase inhibitors, citrates, and sodium bicarbonate are used in the treatment process, the main ingredient is excreted in the urine.
It is not recommended to simultaneously use Furagin and products containing magnesium trisilicate. Otherwise, there is a decrease in the absorption of the drug and a minimization of its pronounced therapeutic effect. It is important to avoid combining Furagin with quinolones (nalidixic and oxolinic acids, Norfloxacin) due to antagonism.
It is also strictly forbidden to simultaneously use the medication in question with Chloramphenicol and Ristomycin.
In this case, the likelihood of unwanted inhibition of the hematopoietic process increases.
With pronounced renal failure Aminoglycosides cannot be used with Furagin.
It is important to remember that when combining of this medicine with MAO inhibitors, as well as food products containing tyramine (some categories alcoholic drinks, cheeses, beans and smoked meats) increases the likelihood of developing a hypertensive crisis, which poses a danger to any person.
With prolonged use of this drug, inhibition of the natural synthesis of B vitamins and folic acid in the body.
In this case, you should contact your personal doctor for advice. If symptoms of neuropathy appear, the medication should be discontinued.
It is indicated on the medicine packaging. It should not be used after the expiration date.
Average cost this drug is 140 rubles. It can be purchased at any pharmacy.
At the moment, there are a large number of substitutes for this drug. Foreign drugs can be considered analogues: Furasol, as well as Furamag.
Drug Furadonin
As noted earlier, it is strictly forbidden to use this drug during pregnancy and breastfeeding. Otherwise, it can cause serious harm to the child's body.
Not recommended for children under six years of age. But starting from this age, you can prescribe this medicine. It is very important to carefully follow the dosage indicated in the instructions.
