Carbomer eye drops. Medicinal reference book geotar

Today, the ecological state of the environment leaves much to be desired. Being in constant smoke leads to constantly drying and burning eyes. Pharmacies have a wide range of eye products, one of them is carbomer. Before using the substance, you need to study the instructions and understand what it is - carbomer.

Pharmacological properties

Carbomer is a high molecular weight substance that interacts with mucin on the cornea. The product is available in the form of a colorless powder. During use, the drug penetrates the corneal epithelium and, thanks to carboxylic acid residues, creates hydrogen bonds in which mucin is present. The main advantage of the product is its adhesive ability in the tear film. As a result of use, a protective layer is formed that moisturizes the cornea, strengthens the mucin layer and gives viscosity to tears.

Carbomers are molecules large sizes, which contain chemical compounds, namely monomers. The main advantage is the absorption and retention of water; during this period they can change in volume and reach large sizes.

In addition to the main characteristics, the carbomer has the following advantages:

  • formation of a moisturizing film;
  • no stickiness;
  • non-toxic.

The product is not mutagenic or teratogenic, this is confirmed by many years of testing. Carbomers do not tend to accumulate or penetrate into eyeball and blood.

Indications for use

Sodium carbomer is prescribed for conjunctivitis and dry eyes. Intended exclusively for symptomatic treatment. Carbomer has other applications, for example:

  • skin products;
  • foot care;
  • toothpastes;
  • cosmetics from the sun.

Before using a thickener, you first need to neutralize it. Without this reaction it is impossible to obtain a viscous consistency. When neutralized, a molecular network is formed that retains moisture. When diluted with liquid, the powder turns into a gel and becomes transparent. Sodium or potassium hydroxide is used to convert the powder into a gel.

Side effects

Before use, it is not enough to know what it is - carbomer, you also need to study side effects means to prevent negative consequences. Improper use may result in burning, tingling and momentary loss vision. If such symptoms appear, it is enough to rinse your eyes with cool and clean water.

Precautions

During the treatment period it is not recommended to use soft contact lenses. Hard ones should also be removed and placed only after fifteen minutes after application. In case it is carried out complex therapy and several eye drops are used at the same time, they should be applied at intervals and the carbomer should be the last.

Those who do not know what carbomer is should consult a doctor and use the substance only for its intended purpose. People who drive a vehicle should wait approximately fifteen minutes after application for their vision to fully recover.

Carbomer in cosmetics

Carbomer is used in cosmetology as a thickener. Most often it is added to pastes, creams, gels and bath products. In addition, it is widely used for the production of decorative eye cosmetics. The use of such cosmetics can cause allergies and inflammation of the eyes.

Carbomer is found in drugs such as:

  1. "Lakropos" - hypersensitive eye drops, used as a tear substitute.
  2. "Sikalos" - eye drops used in the diagnosis of "dry eye".
  3. "Oftagel" - a preparation for education artificial tears. Also, during the period of use, the viscosity of tears increases.

In addition, there are many cosmetics based on carbomers.

Carbomer is mainly used in powder form. Once diluted with liquid, it turns into a viscous emulsion, which is used as a thickener. During the dilution period, the substance does not lose its properties and useful qualities. The main advantage of such cosmetics is moisture retention. Creams made on the basis of carbomer refresh and soothe the skin without creating a greasy film.

Due to the fact that carbomer can cause allergic reaction, the question arises as to what other harm it could cause. What is carbomer? This is an inert substance that is added to medicines and cosmetics in minimal quantities. That is why the harm from its use is also minimized. But still adverse reactions and contraindications exist, and before using the product, you need to mandatory consult your doctor.

Cross-linked allylpentaerythritol high molecular weight polyacrylate .

Chemical properties

Carbomer is a long-chain polymer with a monomer unit of acrylic acid . High molecular weight polyacrylate By physical properties is a moderately opalescent, colorless gel.

Except medical use, Carbomer is widely used in cosmetics. Due to the ability of the substance to form stable emulsions when combined with water, it is added as a structure former and thickener to give cosmetics the necessary viscosity. Carbomer is usually added in small quantities. The substance has a moisturizing effect and soothes the skin. The product is included in various gels, creams and shampoos.

Pharmacological action

Hydrating.

Pharmacodynamics and pharmacokinetics

When Carbomer gets on the cornea of ​​the eye, it interacts with the layer mucin . At the same time, the remainder carboxylic acid With mucin form hydrogen bonds and those parts of the Carbomer that are more ionized attract and retain water. There are electrostatic forces between the ionized molecules and the water molecule. Thus, the substance exhibits adhesive ability and forms a moisturizing film on the corneal epithelium. The mucin layer thickens, the water layer and tear viscosity increase, which has a positive effect on the condition of the cornea and the functioning of the eye as a whole.

The drug is not toxic, does not have mutagenic or teratogenic properties (experiments on rabbits). The substance is not absorbed and does not penetrate the eyeball or systemic circulation. Does not accumulate.

Indications for use

Carbomer is used:

  • for the treatment of dry eyes, dry keratoconjunctivitis ;
  • with other bacterial, fungal and inflammatory diseases eyes;
  • for eye restoration after injuries, erosions of the cornea and conjunctiva.

Contraindications

The product is contraindicated when used on Carbomer.

Side effects

May be observed:

  • allergic reactions, burning sensation;
  • short-term blurred vision;
  • local irritation and discomfort.

Instructions for use (Method and dosage)

Preparations based on Carbomer are prescribed conjunctivally. Usually the medicine is used 2 times a day, once at night.

Overdose

An overdose of the substance is unlikely. There is no information about such cases.

Interaction

After using Carbomer, you must wait 15 minutes and only then can you instill other eye medications.

Terms of sale

No recipe needed.

Special instructions

Due to the fact that this substance may cause short-term blurred vision and decreased vision, you should wait until full recovery vision.

During pregnancy and lactation

Drugs containing (Analogs)

The product is included in the preparations: Lakropos , Sikapos , . Various cosmetics, cream with Carbomer for feet, gels, etc. are also on sale.

It is impossible for a modern person to imagine his life without cosmetics. These are decorative cosmetics - eye shadow, lipstick, mascara, foundation; caring - creams, lotions, sprays; non-medicinal products affecting the condition of the skin, hair, nails; hair and body washes and much more. But the dangerous effects on health of the chemicals in their composition, such as carbomer in cosmetics and sodium lauryl sulfate, are not taken into account.

Trying to emphasize their attractiveness, hide imperfections, and maintain youthful skin, everyone buys various cosmetics for the face and body. But, unfortunately, many personal care products contain dangerous preservatives, synthetic substances, and toxic ingredients. Harm from cosmetics can manifest itself in the form of allergies, various damages skin, diseases internal organs. Some substances immediately cause negative reaction body, and a person can stop using a cosmetic product in time. Others accumulate gradually, and a delayed reaction is possible. At the same time, everything excipients are divided into groups such as:

  1. Preservatives - extend shelf life and prevent the development of microorganisms in personal care products.
  2. Emulsifiers - help create a homogeneous mass and mix components.
  3. Flavorings - add flavor.
  4. Fillers provide the necessary concentration and increase in volume. Their use is beneficial for manufacturers, as the cost of cosmetic products is reduced.
  5. Dyes - give the required shade to the product. Natural products do not allow to achieve beautiful flowers. Therefore, synthetic dyes and bleaches are used.

Of course, such a crude mixture, alien to the body, does not bring any benefit to it and only harms, provoking various irritations and sometimes diseases.

Synthetic substances have a wide variety of destructive effects on human health. Due to incorrectly selected cosmetics, various reactions are possible:

It’s worth talking about the black list of ingredients that are harmful to health, which are included in most cosmetic gels, ointments, etc. After all, hoping to hide problems, prolong youth and freshness of appearance, and emphasize attractiveness, people constantly buy new cosmetics. At the same time, many consumers do not even suspect what exactly they are applying to their skin and body in general, and what consequences this leads to.

Unfortunately, few people are interested in what exactly side effects give substances contained in various cosmetics. Meanwhile, the most common of them, which are listed below, can cause serious damage to a person’s health and well-being:

1. Carboxypolymethylene, in international classification The terms used are Carbomer, Carbopol. Polymer derived from acrylic acid. White powder, odorless. An emulsifier that reacts with fat components creates stable emulsions in water. Contains benzene and acrylic acid. Carbomer is used in cosmetics as a thickener for shampoos, gels, and creams.

It creates a comfortable gel-like structure that consumers love so much. Has a moisturizing, refreshing, soothing effect on the skin. Carbopol in cosmetics makes it possible to maintain the attractiveness and transparency of shampoos and gels when adding highly active substances to them - fragrances, vitamins, essential oils. Thanks to it, gels and creams do not flow like water, do not separate, do not dry out, and retain color throughout the entire shelf life. In ophthalmology it is used to create artificial tears.

2. Kaolin in cosmetics - white clay, used in face masks and decorative cosmetics. Retains carbon dioxide and toxins in the skin, clogs pores. It dries and dehydrates the skin, deprives it of oxygen, and causes premature aging.

3. Lanolin - animal wax, wool wax, collected from sheep's wool. Contains large number pesticides, harmful to skin. Reacts with carcinogenic substances, allows them through skin enter the human body.

4. Germaben - a preservative contained in cosmetics that are used daily - toothpaste, cleansers, gels for intimate hygiene, lotions and creams. Antimicrobial, bacteriostatic, antifungal substance. May cause the development of:

  • breast cancer;
  • early puberty;
  • allergies, skin diseases.

5. Triethanolamine - known for its concentrating properties. Included in decorative cosmetics - blush, eyeliner, foundation, mascara, eye shadow. It can be found in shampoos and hair masks, hair dyes. Triethalamine is widely used in perfumes, lotions, and body tanning creams. It penetrates the skin, accumulates in it, and exhibits toxic properties over time, causing:

  • formation of malignant tumors;
  • development of diseases gastrointestinal tract, kidneys, cardiovascular system;
  • skin irritation, allergies;
  • redness and irritation of the eyes.

In cosmetics that have long-term contact with the skin (creams, decorative cosmetics), the concentration of triethalamine should not exceed 5%.

6. Sodium Lauryl Sulfate (SLS) - foaming agent, viscosity and consistency regulator. The most dangerous substance, included in bath foam, shampoo, shower gel, shaving foam, toothpaste, skin cleansers. Possessing strong cleansing and degreasing properties, it quickly penetrates the skin and accumulates in the kidneys and liver. Daily use of this substance leads to:

  • peeling, irritation, swelling of the skin;
  • occurrence of dandruff, weakening hair follicle, fragility and hair loss;
  • changes in the whites of the eyes, causing the formation of cataracts;
  • the formation of nitrates, which destroy the human body.

Gel, lotion, lipstick, foundation, eye shadow, mascara, powder, face and body care cream, shampoo, bath foam, cosmetic masks... The list of cosmetology products that are used every day can be long. The cherished desire to get rid of old, dry, oily and sagging skin, to have healthy and lush hair, to look impressive and attractive is being exploited with pleasure by manufacturers of cosmetic products who are silent about harmful effects synthetic substances used in the production of cosmetics affect human health.

Choose only safe products for yourself and your loved ones. Do not use products containing substances potentially hazardous to life and health. Stop using cosmetics if allergic rashes, itching, redness, deterioration in the natural condition of the skin and well-being, or conjunctivitis appear. You should be especially careful when choosing safe cosmetics for children. In “natural” or “natural” cosmetics, other than those advertised natural ingredients, also often contain dangerous chemicals and harmful compounds.

When it comes to health, you should not follow the principle “beauty requires sacrifice”!

Formula, chemical name: Carbomer is a high molecular weight polyacrylate cross-linked with allyl pentaerythritol.
Pharmacological group: Metabolics/rehydrants.
Pharmacological action: hydrating.

Pharmacological properties

The carbomer on the corneal epithelium reacts with the mucin layer, and hydrogen bonds are formed between the mucin molecules and non-ionized carboxylic acid residues in the polymer, and the areas of the carbomer that are more ionized due to electrostatic forces hold water around the molecule. Carbomer has a pronounced adhesive ability to the mucin layer in the tear film and epithelial membranes. Carbomer forms a moisturizing protective film on the cornea, thickens the aqueous and mucin layers of the tear film, and increases tear viscosity. A pronounced moisturizing effect and prolonged contact with the cornea determine the effectiveness of carbomer in conditions that are accompanied by changes in the properties of mucin (acute respiratory diseases, infectious, including fungal, bacterial and inflammatory eye pathologies), with erosions and injuries of the cornea and conjunctiva, with decreased tear secretion. During experimental studies of the safety and tolerability of carbomer 974P (use 4 times daily for 4 weeks or single instillation in rabbits), negative systemic or local action was not identified. No mutagenic or teratogenic properties of carbomer were detected. Carbomer is not subject to systemic absorption from the tear ducts, does not pass into the eye tissue and does not accumulate in them.

Indications

Dry eyes ( symptomatic therapy), dry keratoconjunctivitis.

Method of administration of carbomer and dose

1 – 4 times a day, inject 1 drop into the affected eye.
Carbomer may cause a temporary decrease in visual acuity, so before starting work, drivers vehicles and people whose professions require visual acuity must wait until visual acuity is fully restored. It is not recommended to wear soft contact lenses during therapy. Before using the drug, you must remove hard contact lenses and reinsert them no earlier than 15 minutes later. When using more than one type of eye dosage forms, they must be applied at intervals of at least 15 minutes, and carbomer should always be administered last.

Contraindications for use

Hypersensitivity.

Restrictions on use

No data available.

Use during pregnancy and breastfeeding

The use of carbomer during pregnancy during breastfeeding is possible if the expected effects of treatment for the mother are higher than the potential risk for the child and fetus.

Side effects of carbomer

Brief tingling sensation transient disorder vision, eye irritation.

Rehabilitation therapy after laser and surgical interventions on the cornea.

Contraindications

infectious diseases eyelids, conjunctiva and cornea;

increased sensitivity to the components of the drug.

Dosage

Oftagel is instilled 1 drop 1-4 times a day depending on the severity of symptoms.

Before using the drug, you must wash your hands; Before instilling Oftagel, the head should be tilted back, the lower eyelid should be pulled back and 1 drop of gel should be dropped into the conjunctival sac between the lower eyelid and the eye.

Do not touch the eye or eyelid with the tip of the pipette. After using the drug, you must immediately close the bottle.

Side effects

Local reactions: Immediately after instillation, transient blurred vision, a short-term burning sensation and local irritation of the eyes are possible.

Overdose

No cases of overdose of Oftagel have been reported.

Drug interactions

Drug interactions of Oftagel with other drugs have not been studied.

Special instructions

Benzalkonium chloride, which is part of the drug, can be absorbed and discolor contact lenses. Therefore, before using Oftagel, contact lenses should be removed and reinserted 30 minutes after instillation of the drug.

If necessary, simultaneous use of other eye drops Oftagel should be instilled last with an interval of at least 15 minutes.

It should be borne in mind that the bottle of the drug is intended for use in only one person.

Impact on the ability to drive vehicles and operate machinery

Oftagel eye gel may cause temporary blurred vision. Before driving a car or operating mechanical devices, you should wait until your visual acuity is fully restored.

Pregnancy and lactation

There have been no adequate controlled studies of the use of Oftagel in pregnant women.

The use of the drug during and during lactation is possible only as prescribed by a doctor in cases where the expected benefit to the mother outweighs the potential risk to the fetus and child.

Conditions for dispensing from pharmacies

The drug is available without a prescription.

Storage conditions and periods

The drug should be stored out of the reach of children, protected from light at a temperature of 15° to 25°C. Shelf life - 30 months. Do not use the drug after the expiration date indicated on the package.

After opening, the bottle with the drug should be stored in a cardboard package upside down (to facilitate the flow of the gel). Shelf life after opening the bottle is 1 month.