Do I need a prescription for Clotrimazole? Instructions for use and prices of clotrimazole tablets

The drug Clotrimazole cream is used for pathologies caused by fungus, for example, vaginal candidiasis or thrush. The main active substance of the product destroys fungal membranes and has a detrimental effect on pathogenic microorganisms. Thanks to the low price and positive feedback, this medicine against fungus is one of the leaders in the pharmacological market.

What is Clotrimazole cream

For fungal diseases of the skin, nails, vaginal candidiasis (thrush) it is prescribed drug therapy antibacterial ointment Clotrimazole. The drug has a strong antifungal effect on pathogens of erythrasma, fungal psoriasis and other common mycotic diseases. The doctor can prescribe an ointment at the first symptoms of infection, to prevent mycosis in the layers of the skin and on the vaginal mucosa.

The drug inhibits the growth, development and division of fungal cells. In addition, the drug is widely used for genital tract infections (for example, vaginal mycosis of the vaginal lining). To treat candidiasis, ointment is prescribed to both sexual partners. In this case, it is recommended to apply the cream both before and immediately after sexual intercourse.

The medicine in the form of a cream is a mass of pale yellow color, the consistency of fatty sour cream, packaged in an aluminum tube and cardboard packaging with an annotation for the medicine, instructions for using the antifungal drug. Clotrimazole ointment is freely available in pharmacies and online stores without a doctor's prescription.

Compound

The drug is available in several dosage forms: vaginal tablets, suppositories, ointment, cream for external use. The latter has the following composition:

  1. The main active ingredient is clotrimazole 10 mg.
  2. Additional substances - ethyl alcohol, petroleum jelly, glycerol, distilled water, solid fat.

Pharmacological action

The drug disrupts the synthesis of ergosterol, which is part of the fungal cell membrane. Clotrimazole inhibits the cell division processes of pathogenic microorganisms and is one of the most effective antifungal agents, because it has wide range actions. The drug has a detrimental effect against gram-positive and gram-negative bacteria. Doctors recommend starting therapy at the first signs of infection.

What is Clotrimazole for?

Clotrimazole cream has the following indications for use:

  • fungal diseases skin;
  • mycoses of the feet, palms, skin folds;
  • pityriasis versicolor;
  • thrush;
  • erythrasma;
  • superficial and deep candidiasis.

Instructions for use Clotrimazole cream

The medicine Clotrimazole is used for external application for antifungal therapy. The medication is applied according to the instructions thin layer 2-3 times/day. on clean and dry areas of skin with affected epidermis. If the skin has serious lesions and ulcers, to achieve best effect It is recommended to use compresses with cream for several days so that the medicine is absorbed into the high concentrations. The duration of the course of therapy depends on the severity of the disease, localization of the pathology, and effectiveness.

For women

A medicine with antifungal activity, Clotrimazole, is used for women suffering from frequent exacerbations of thrush, vaginitis and other bacterial lesions of the vagina. The duration of treatment is from 5 to 10 days, depending on the severity of the disease. Clotrimazole is recommended for the prevention of exacerbations of candidiasis during colds and reduction general immunity. The drug should be used with caution during menstruation.

For men

Clotrimazole cream for men is used mainly for the treatment of chronic and acute form candidiasis lesions of the genital skin. Treatment of fungal diseases in men lasts from 4 to 7 days. It is better to start using the cream when the first signs of the disease appear: severe itching, burning, redness, pain when urinating. Good genital hygiene also helps. The cream should not be used if you are hypersensitive to the components of the drug.

Drug interactions

Some drugs (Amphotericin B, Nystatin) significantly reduce the effectiveness of Clotrimazole during simultaneous drug therapy, so they do not need to be used together. When using the medication, negative interactions with other drugs result clinical trials was not identified. Caution should be used when using the cream simultaneously with other antibiotic ointments, since the combination different groups antifungal drugs may lead to allergies.

Side effects and overdose

When using a cream with Clotrimazole, local adverse reactions are often observed: itching, burning, redness of the skin at the sites of application medicine. In some cases, blisters, erythema, swelling and peeling of the skin appear. Individual intolerance to the drug is manifested by urticaria. The use of the drug in high doses does not cause life-threatening or health-threatening conditions.

Contraindications

The use of Clotrimazole is strictly contraindicated if the patient has a history of:

Special instructions

The antibiotic Clotrimazole is intended strictly for external use for fungal infections and other skin diseases. The medicinal product is not suitable for use in ophthalmological practice, contact of the cream with the eyes and the skin around them should be avoided. The drug should be used with caution in children under 5 years of age. Do not allow the cream to get into open wounds or damaged mucous membranes. When the first signs of an allergic reaction appear, drug therapy with the drug must be stopped.

Pregnancy and lactation

No toxic effects of the drug on the fetus have been identified; use is relatively safe at all stages of pregnancy. Therapeutic doses of the drug do not affect fetal development. It is recommended to use Сlotrimazole for the prevention of fungal infections for women in the first trimester of pregnancy who have an unfavorable permanent environment (for example, if a girl works in kindergarten or medical institution). Application during breastfeeding It is not prohibited if the cream does not come into contact with the mammary glands.

Analogs

Present on the pharmaceutical market large number medications that are similar in their effect to Clotrimazole, but differ in release form, price, and composition. Some may cause fewer side effects or work faster. The main analogues of Clotrimazole are:

  1. Candide. An antifungal medication that has a wide spectrum of action against fungal microorganisms. The main active substance of Candida, clotrimazole, is a form of the substance imidazole. Due to the fact that the drug damages the membranes of fungal cells, according to reviews, it is considered one of the best antifungal agents. The cost of the medicine is about 80 rubles.
  2. Kanizon. The drug has fungistatic and fungicidal effects, the manifestation of which depends on the doses of the drug used. The following groups of fungi are sensitive to the drug Kanizon: dermatophytes, moldy fungi, blastomycetes and dysmorphic fungi, actinomycetes. The active component inhibits the synthesis of molecules of the substance ergosterol, which is necessary for the formation of cell walls of pathogenic microorganisms. The price of the medicine is on average 75 rubles per package.

Price

Before purchasing the drug, it is advisable to find out how much Clotrimazole costs, compare prices, and choose the lowest one. You can order the drug in the online store using the proposed catalog. The cost of Clotrimazole depends on several factors:

  • percentage of active ingredient;
  • Clotrimazole concentrations;
  • the nature and quality of additional ingredients;
  • manufacturing company.

Video

Every woman has encountered this at least once in her life. gynecological problem, like candidiasis, or thrush. This disease brings a lot of discomfort and inconvenience and leaves behind quite unpleasant memories.

Thrush is infectious disease, which affects the mucous membrane of the genital organs in adults and oral cavity in children. The disease develops against a background of weakened immunity, vitamin deficiency, obesity, diabetes mellitus and during pregnancy. Characteristic signs of this disease- itching and cheesy coating white With unpleasant smell. To treat this disease, it is necessary to select antifungal drugs. Clotrimazole ointment is considered one of the most popular and effective medicines today. For genital thrush, this medication is widely used in the form of vaginal tablets.

In this article we'll talk about how to use this drug correctly, what contraindications and side effects it has.

Warning

This description and recommendations on how to use Clotrimazole for thrush can only be used as a source of information. The drug can only be prescribed qualified specialist after the appropriate laboratory tests and an accurate diagnosis was established.

The drug "Clotrimazole" - instructions

For thrush, it is very important to choose the right medicine that contains an active component that can act on the specific type of fungus that caused the problem. The active component in the drug "Clotrimazole" is an imidazole derivative. This substance has the ability to disrupt the synthesis of certain substances in the human body, in particular, it inhibits the formation of cell membranes of the thrush pathogen. In other words, the drug simply prevents the disease from developing and kills the fungus.

Purpose and release form

The drug "Clotrimazole" has a wide variety of release forms. All these drugs are effective in combating mycotic diseases caused by Candida type fungus in adults and children:

What is the difference between ointment and cream? The difference lies in the special action. The ointment is thicker and is well suited in cases where one of the manifestations of thrush is dry skin and mucous membranes. If there is abundant cheesy discharge, it is better to give preference to a cream that will slightly dry out the areas of the mucous membrane affected by the fungus. In each individual case, your attending physician will help you decide on the form of the drug.

How does the drug work?

The effect of the drug "Clotrimazole" for thrush in women is due to the fact that the active component in the composition of the drug destroys metabolic processes, associated with ergosterol - the basis of the structure of fungi. As a result, the environment for pathogens becomes toxic and they die.

In addition to the Candida type fungus, the active component of the drug has an effect on the division of bacteria such as streptococci, staphylococci, gardnerella and trichomonas. But against formed microorganisms, the drug “Clotrimazole” is weakly effective.

Absorption of the drug through the skin and mucous membranes is only 3-10%. In the liver, during the process of transformation, it ceases to be active and is excreted from the body in feces. After using the drug, its presence in the body can be monitored for 2-3 days.

Indications for use

The use of Clotrimazole for thrush is always local. The active component of the product gives good result for the following diseases:

  • thrush;
  • skin fungus (trichophytia, lichen);
  • bacterial infections (streptoderma, pyoderma);
  • foot fungus (onychomycosis, paronychia, interdigital fungus);
  • trichomoniasis.

Instructions for use this tool clearly describes how the drug should be used.

Each form of release of the drug has its own application characteristics:

Before using Clotrimazole, you must carry out hygiene procedures. To clean the external genitalia during illness, you should use products with a neutral pH so as not to further damage the mucous membrane. During the treatment period, it is necessary to limit the consumption of sweets, as well as spicy and fatty foods.

Contraindications for use

The drug is strictly prohibited for people with impaired liver function, since it is the liver that is involved in the process of removing the drug from the body. Its use is also undesirable for pathologies of the hematopoietic organs, including iron deficiency anemia. The drug "Clotrimazole" is not prescribed to children under six years of age. Sensitivity to the components in the product is also a contraindication.

Overdose and negative effects

If the recommended doses are exceeded, allergic reactions to Clotrimazole may develop. Tablets for thrush are used only vaginally; when taken internally, nausea, vomiting and stomach pain are inevitable. In such conditions, it is necessary to rinse.

When using Clotrimazole (ointment) for thrush, irritation on the skin and mucous membranes may occur, including swelling and redness, which may be accompanied by itching and pain. These phenomena cannot be ignored, and adverse reactions You should immediately consult a doctor and stop taking Clotrimazole if you have thrush.

Clotrimazole ointment can rightfully be called universal drug from a fungal infection.

Its wide spectrum of action allows it to affect various types fungal pathogens, including those that infect scalp head or genital area. This drug has been on the pharmaceutical market for quite a long time, it is produced by various domestic and foreign manufacturers, has an affordable price, has a lot of structural analogues, and can be used in combination with other pharmaceutical drugs.

On this page you will find all the information about Clotrimazole: full instructions on application to this drug, average prices in pharmacies, complete and incomplete analogues of the drug, as well as reviews of people who have already used Clotrimazole ointment. Would you like to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Antifungal drug for external use.

Conditions for dispensing from pharmacies

Available without a prescription.

Prices

How much does Clotrimazole ointment cost? Average price in pharmacies it is at the level of 47 rubles.

Release form and composition

Clotrimazole ointment has a white or almost white color, a uniform structure and a dense consistency. The main active ingredient of the drug is clotrimazole, its content in 1 g of ointment is 10 mg.

Auxiliary components of the ointment are:

  • Methyl parahydroxybenzoate.
  • Polyethylene oxide 1500.
  • Propylene glycol.
  • Methylparaben.

It is in an aluminum tube in the amount of 30 g. The cardboard box contains one aluminum tube with ointment and instructions for using the drug.

Pharmacological effect

Clotrimazole is a drug with pronounced antifungal properties, which belongs to the imidazole derivative. The use of the drug makes it possible to inhibit the synthesis of ergosterol, thereby disrupting the permeability of fungal cells, causing their death. Clotrimazole - the active component of the ointment is effective against dermatophytes, yeast, mold fungi, has antibacterial effect with staphylococcal, streptococcal infection. Use this drug possible with various diseases fungal nature.

After application to the skin, the active component is quickly absorbed into the upper and deep layers of the epidermis and practically does not penetrate into the bloodstream. A special feature of the drug is the fact that after use therapeutic effect It will not be noticeable immediately, but after a while. However, with long-term use, the effect of the drug will be 100%. It is very important to maintain skin hygiene when using the ointment, and also not to skip its use.

This ointment not only allows you to get rid of a fungal infection, but also significantly reduces infection of the skin with other bacteria, which often complicate the treatment process and the course of the disease.

Indications for use

What does it help with? Clotrimazole ointment has antifungal effect, but can not only kill the fungus - the active substances also have a detrimental effect on other pathogenic microorganisms that negatively affect general condition human health.

Indications for the use of Clotrimazole ointment are:

  • paronychia;
  • combined infection of candidiasis + trichomoniasis;
  • dermatophytosis and other fungal infections.

This ointment is often prescribed for treatment - the fungi that cause this disease are very sensitive to the main active substance funds and are therefore destroyed relatively quickly. Medicine knows of cases where Clotrimazole ointment helped get rid of severe pigmentation, despite the fact that it is exclusively an antifungal agent.

The drug in question copes well with both.

Contraindications

Allergic reactions or hypersensitivity to the active substance of the drug or to its other components, menstrual period(for vaginal use).

Children are allowed from 2 years old.

Instructions for use

The instructions for use indicate that Clotrimazole Ointment for external use is applied to clean, affected areas of the skin in a thin layer several times a day, gently rubbing. The duration of treatment depends on the location, severity of the disease and the effectiveness of therapy:

  1. Dermatomycosis is treated for at least a month;
  2. Pityriasis versicolor – up to three weeks;
  3. Fungal diseases of the skin of the feet - therapy is continued for at least two weeks after the symptoms have passed.

Clotrimazole cream can also be used to treat these diseases.

After applying Clotrimazole ointment, do not apply sealed bandages.

Side effects

When Clotrimazole ointment is used externally, swelling may occur, as well as burning, peeling or irritation of the skin, itching, erythematous rashes, paresthesia, blistering or urticaria.

Overdose

To date, no cases of overdose with Clotrimazole ointment have been reported.

Special instructions

  1. It is not recommended to apply the drug to the skin in the eye area.
  2. If there is no effect within 3 days, the diagnosis should be confirmed.
  3. If signs of hypersensitivity or irritation appear, treatment is stopped.
  4. In patients with liver failure The functional state of the liver should be periodically monitored.

Drug interactions

Amphotericin B, nystatin, natamycin reduce the effectiveness of clotrimazole when used simultaneously.

When using ointment negative interactions with other means are unknown and should not be expected, because The resorption capacity of clotrimazole is very low.

Reviews

We have selected some reviews from people who have used Clotrimazole ointment:

  1. Natasha. For more than 20 years now, fungus-like spots have periodically (4 months to half a year) appeared on my neck. I consulted a doctor, she prescribed me Exifin ointment. I’ll go through a course of treatment and everything seems to be going away. After 4-5 months it appears again. I smear again. And then I told about my problem at the pharmacy, they advised me to kill the fungus from the inside, offering me a Flucanazole capsule. I drank it, and three months later I drank another one, just to be sure. And nothing happened! Well, what kind of rubbish is sitting inside me that nothing beats it? I want to try Clotrimazole ointment. According to rumors, the ointment is not bad. I hope it helps!
  2. Kate . Clotrimazole was used to treat nail fungus. I caught it during pregnancy. Periodically rubbed the ointment into the nail and trimmed the affected area. I applied it a total of 10 times. Six months later, a healthy nail grew back.
  3. Zoya. I was very surprised when on the third day the fingers became as good as new, but the soles were moving more slowly. Before that I tried all the folk remedies and then it only got worse. The growths became thick, rough yellow, and even worse they began to crack and it became painful to step on until it bled. sole. And thunder struck, I turned to the Internet and read about the drug CLOTRIMAZOL ointment, there were others, but it seemed to me that it had a wider spectrum and I was very surprised that it cost 30 rubles. The most important thing after that was that I believed in medicine and will definitely go to the hospital to find out more diagnosis and cure to the end. Of course, I didn’t come down from the mountains and medicine even saved my life more than once, but as we think, small troubles in the form of small cracks on the foot are nonsense, we will cure ourselves, but no such luck, it’s a fungus. I’m writing for everyone who will read, don’t wait Don’t waste time on random advice, they are all good only for prevention, but if fungus has already appeared, run to the doctor. Well, I came across this drug and it helped me.
  4. Margarita. I suffered for a long time with ringworm, I tried almost everything possible means traditional medicine ( laundry soap, soda, iodine, herbs) and expensive medicines. The doctor prescribed a very cheap cream, Clotrimazole, for treatment. I was very surprised - after the first week of use, the skin began to smooth out, and after three weeks everything went away.

Analogs

Are there any analogues for Clotrimazole ointment? Certainly. They can be divided into two groups: with an identical active substance and with a different one. The first group includes:

  • Amyclone;
  • Candide;
  • Candide - B;
  • Kandibene;
  • Kanesten;
  • Kanizon;
  • Imidyl.

Like Clotrimazole, the listed drugs also have other forms of release, in addition to cream.

The second group includes the following ointments:

  • Pimafucin (active ingredient natamycin);
  • Lamisil (terbinafine);
  • Terbizil (terbinafine);
  • Fungoterbine (terbinafine);
  • Fucis (fluconazole) and other analogues.

Before using analogues, consult your doctor.

Storage conditions and shelf life

The shelf life of Clotrimazole ointment is 2 years from the date of its manufacture.

The drug must be stored out of the reach of children at an air temperature no higher than +20º C. The ointment should not be allowed to freeze.

Almost every person faces such a problem as thrush. It appears suddenly, as if out of nowhere, and brings a lot of trouble, causing harm to health. Clotrimazole will help get rid of this disease.

What is thrush

What is thrush? This fungal disease, caused by special opportunistic microorganisms Candida, which live even in the healthy microflora of the human mucosa. The disease begins when a colony of yeast-like fungi begins to grow rapidly.

This phenomenon is associated with a violation protective properties body. Often due to a long-term illness, against the background of long-term use of antibiotic and/or hormonal drugs, or due to the person’s prolonged exposure to extreme conditions for him stressful situations. The occurrence of thrush (in other words, vaginal candidiasis) can be affected by:

  • chronic diseases;
  • metabolic diseases;
  • allergy;
  • pregnancy;
  • lack of personal hygiene;
  • strict diets;
  • immunodeficiency;
  • oncology;
  • frequent and long-term use tampons;
  • wearing synthetic tight-fitting underwear;
  • course of chemotherapy.

As a result, the natural balance is disrupted, and the candida fungus begins to grow, damaging the mucous membranes and skin.

Thrush doesn't count dangerous disease, but in the absence of proper treatment it can manifest itself as a catalyst quite serious problems with health.

About thrush (candidiasis): video

The effectiveness of Clotrimazole in the fight against thrush

Vaginal candidiasis requires complex treatment: local and internal. Precisely timely therapeutic actions will help avoid serious complications.

This is often used in the treatment of thrush in women, men and children. universal remedy external action as Clotrimazole. This is a simple but effective drug that is effective in the treatment of not only candidiasis, but also kills a number of pathogenic microbes, such as staphylococci, streptococci. It eliminates the symptoms accompanying the disease:

  • white cheesy coating;
  • swelling;
  • soreness;
  • hyperemia.

You should not expect a quick result, however, by following the clear instructions of your doctor, you can achieve complete cure. At the same time, the cost of the drug is low. A combination of several forms of Clotrimazole will speed up recovery.

The effectiveness of the drug is based on the effect active substance on ergosterol, which is part of the fungal membrane. It makes you lose them nutrients, which ultimately leads to death. Clotrimazole affects those microorganisms that grow by fission. It destroys candida cells and spores, paralyzing their vital functions.

Minimum doses and irregular use only lead to blocking the spread of thrush. Complete extermination of pathogens is possible only with integrated approach, high doses and following doctor's recommendations.

Composition and release forms

Clotrimazole is an antifungal and synthetic antibacterial agents. The active component is 1-[(2-Chlorophenyl) diphenyl methyl]-1H-imidazole (C22H17ClN2). It is a white crystalline substance, odorless and insoluble in water.

The drug Clotrimazole is produced in different pharmaceutical companies all over the world. There are several forms of this medicine:

All these types of Clotrimazole are used externally or intravaginally (for women).

Forms of Clotrimazole and their additional components

Since there is a wide variety of release forms, the components (additional components) are different.

Cream

Clotrimazole cream 1 and 2% is used in the treatment of thrush in men and women. Its advantages:

The cream contains the following auxiliary components:

  • liquid paraffin;
  • ketosteryl alcohol;
  • white soft paraffin;
  • ketomacrogol 1000;
  • purified water;
  • chlorocresol;
  • disodium edetate;
  • citric acid;
  • dibasic sodium phosphate (anhydrous);
  • propylene glycol;
  • sodium metabisulfite.

Vaginal suppositories

The most common form of treatment for thrush in women is vaginal suppositories (candles). Features of this type of Clotrimazole:


In addition to the active ingredient, vaginal suppositories contain semi-synthetic glycerides (solid fats).

Gel for external use

Gel - new form Clotrimazole. This is a homogeneous white substance for topical use. This product is quickly absorbed, slightly drying the affected areas.

The gel contains:

  • cetyl alcohol;
  • propylene glycol;
  • glycerol;
  • benzyl alcohol;
  • cetomacrohead emulsion wax;
  • carbomer 940;
  • sodium hydroxide;
  • chlorocresol;
  • purified water.

Liquid form of Clotrimazole: solution

The solution appeared relatively recently on the pharmaceutical market, so it has not yet received wide application in the treatment of thrush. It is a clear, slightly viscous liquid with an alcoholic odor.

This product contains additional components present:

  • benzyl alcohol;
  • propylene glycol;
  • 2-octyldodecanol;
  • polyethylene glycol 400;
  • sodium citrate;
  • isopropyl alcohol;
  • water.

Clotrimazole-Akrikhin ointment

Ointment is often used to treat thrush. The most popular is Clotrimazole-Akrikhin from Russian manufacturer. This inexpensive remedy in the line of drugs of this type. The ointment quickly envelops the mucous membrane, softening dry damaged areas. Its effectiveness is about 90%.

Auxiliary components of the ointment are:

  • propylene glycol;
  • polyethylene oxide 1500;
  • polyethylene oxide 400;
  • nipagin (methyl parahydroxybenzoate).

Vaginal tablets

IN lately Doctors often recommend using Clotrimazole tablets for intravaginal use. Their advantage is the absence of a greasy base. However, the cost of vaginal tablets is slightly higher than other pharmaceutical forms of Clotrimazole.

Additional components of vaginal tablets are:

  • lactose monohydrate;
  • potato starch;
  • adipic acid;
  • sodium bicarbonate;
  • magnesium stearate;
  • colloidal silicon dioxide;
  • sodium lauryl sulfate.

Many packages of this medicine contain a special applicator for introducing the drug deep into the vagina.

Spray

Clotrimazole spray is gaining popularity. 1-2 sprays are enough to cover the entire outer surface genitals. It is often used by men in the treatment of thrush.

In addition to the active substance, it contains:

  • isopropyl myristate;
  • ethanol.

Restrictions and contraindications: can it be used during pregnancy?

Like everyone else medicines, Clotrimazole has a number of adverse reactions and contraindications for use.

Contraindications

All forms of Clotrimazole cannot be used in the following cases:


Restrictions

Use this product with caution:

  • during pregnancy in the 2nd and 3rd trimester;
  • during lactation;
  • in the presence of chronic liver failure;
  • if the patient's age is above 60 years;
  • against the background of pathology of the hematopoietic organs;
  • during colds accompanied by fever and increased body temperature.

Adverse reactions

Clotrimazole is usually easily tolerated by patients, without causing serious adverse reactions. It happens that when the recommended doses are exceeded, there are negative reactions body.

May be observed:

  • redness of the mucous membrane;
  • burning and tingling sensation at the application sites;
  • hives;
  • irritation;
  • nausea turning into vomiting;
  • the appearance of edema;
  • cystitis;
  • peeling of the skin;
  • frequent urination;
  • pain during sexual intercourse;
  • headache;
  • discharge from the genitals.

Special conditions

There are special conditions when the use of Clotrimazole is undesirable:

  • the use of certain drugs: Nystatin and Natamycin;
  • use of other vaginal products;
  • consumption of alcoholic beverages;
  • unprotected sex.

The drug Clotrimazole and all its structural analogues, including Clotrimazole-Akrikhin, are available over-the-counter. However, this does not mean that you can get carried away with self-medication. Only a doctor after diagnosing thrush can prescribe this remedy.. The course of therapy does not exceed 4 weeks and depends on the dose of this medicine. Regularity - at least 2 times a day.

If after the first week of use there is no improvement, then you should contact your doctor to change the medication.

How to use for women

Women can use Clotrimazole cream, ointment, suppositories and vaginal tablets as follows:

  1. Lying on your back, bending your knees and spreading them apart, you need to insert the product deep into the vagina.
  2. If you have a special applicator, then this manipulation can be carried out with its help.
  3. After administering the drug, you should lie down for a while (at least 30 minutes).
  4. To prevent the medicine from leaving stains on your underwear, it is recommended to use panty liners, but never tampons.
  5. When using tablets, they must first be slightly soaked in warm water.

Often, a doctor prescribes several types of drugs simultaneously to treat thrush. In such cases, it is necessary to take into account the consistency of each form. It is advisable to use ointment and/or suppositories before bedtime, and cream, gel, solution and tablets - in the morning and daytime.

How to use the product for men

Naturally, in the treatment of thrush in men, such forms of Clotrimazole as ointment, cream and solution are used. In order to prevent relapse, treatment of both partners is mandatory.

An untreated disease may further cause the development of dangerous pathologies, such as vesiculitis and prostatitis.

Although thrush is considered female disease, Candida fungi are capable of taking root on male genitals with reduced immunity. Therefore, when a partner is diagnosed with thrush, it is necessary to compulsory treatment. As a rule, a urologist prescribes Clotrimazole to men twice a day. In this case, an ointment, solution or cream is applied to the clean head of the penis.

Use for prophylactic purposes

Clotrimazole is not used as a prophylactic agent for suppression possible occurrence fungal infection, but is periodically used for sanitation birth canal on the eve of the birth of the child.

Analogues of Clotrimazole in the treatment of thrush

If for some reason this drug cannot be used, the doctor has the right to replace the drug with an analogue that does not contain clotrimazole.

Drug analogues - table

Drug name Release forms Active ingredient Indications for use Contraindications Side effects Use during pregnancy Average cost and manufacturers
  • cream;
  • powder;
  • solution for external use;
  • spray.
bifonazoleCandidiasis:
  • nails;
  • vagina;
  • skin;
  • diaper rash;
  • dermatophytosis.
  • hypersensitivity;
  • infancy.
allergic reactionswith caution
  • spray - about 120 rubles;
  • powder - 30 rubles;
  • cream - up to 70 rub.

Manufacturer Sintez OJSC (Russia)

  • cream;
  • vaginal suppositories;
  • vaginal tablets.
omoconazole
  • candidiasis;
  • pityriasis versicolor;
  • seborrhea;
  • erythrasma.
  • burning;
  • vaginal suppositories and tablets - up to 900 rubles;
  • cream - up to 400 rub.

Manufacturer Teva Pharmaceutical Works Co. Ltd. (Hungary)

Pimafucin
  • vaginal suppositories;
  • cream;
  • enteric tablets.
natamycin
  • various types of candidiasis;
  • otomycosis;
  • dermatomycosis;
  • otitis complicated by fungi.
  • nausea;
  • diarrhea;
  • mild irritation;
  • burning.
allowed
  • tablets - up to 500 rubles;
  • cream - within 350 rubles;
  • suppositories - up to 510 rub. for 6 pcs.;
  • tablets - about 450 rub.

Manufacturers:

  • Temmler Italia S.r.L. (Italy);
  • Astellas Pharma CJSC (Russia).
Neo-Penotranvaginal suppositories
  • metronidazole;
  • miconazole
  • vaginal candidiasis;
  • trichomoniasis;
  • inflammatory process of the reproductive organs.
average price - 900 rub.
Manufacturer: Embil Pharmaceutical Co. (Türkiye)
Nystatin
  • ointment for external use;
  • vaginal suppositories;
  • rectal suppositories;
  • pills.
nystatindiseases caused by fungi, including candidiasis of various etiologies
  • pancreatitis;
  • renal and liver failure;
  • stomach ulcer;
  • Pimafucin is an analogue of Clotrimazole, not suitable for everyone. Micogal is one of the the best means in the treatment of candidiasis
    Bifosin is rarely used in the treatment of vaginal candidiasis

Content

To eliminate the causative agents of lichen, for fungal infections it is prescribed antibacterial drug Clotrimazole - instructions for use of which include information on dosage and method of use. This medication with an antimycotic effect is not an antibiotic, but has a detrimental effect on microorganisms. Familiarize yourself with the indications for its use, possible side effects described in the instructions.

Clotrimazole for fungus

According to the pharmacological classification, Clotrimazole is part of a group of drugs with an antifungal effect and a wide spectrum of action. With its help, you can eliminate the signs of multi-colored lichen, fungal manifestations on the skin and mucous membranes of the genital tract. A product with an antimycotic effect is used topically, externally or intravaginally, and has several different forms release. It is allowed to be used by children and adults.

Composition and release form

There are six forms of medication: cream, ointment, gel, solution, vaginal suppositories and tablets. Check out detailed composition each medicine:

Clotrimazole concentration

Auxiliary components

Description

Package

1 g per 100 g

Cetostearyl and benzyl alcohol, sorbitan stearate, octyldodecanol, polysorbate, water, synthetic spermaceti

White, uniform

Aluminum tube 20 g

Monoglycerides, cetostearyl alcohol, castor oil, emulsion wax, polysorbate, glycerol, methyl and propyl parahydroxybenzoate, propylene glycol, water

White-yellowish with a faint odor

15 and 30 g aluminum tubes

10 mg per 1 g

Ethanol, glycerol, macrogol, carbomer, sage extract, propylene glycol

Homogeneous transparent gel with sage scent

20 and 40 g aluminum tubes

10 mg per 1 ml

Ethanol, propylene glycol, polyethylene glycol

Transparent colorless liquid

25 ml, glass bottles with applicators

Vaginal suppositories

100 mg per 1 piece.

Semi-synthetic glycerides

Cylindroconical shape, white-yellow color, cut with an air core or funnel-shaped depression

6 pcs. in blister packs

Vaginal tablets

Magnesium stearate, adipic acid, lactose monohydrate, sodium bicarbonate, potato starch, sodium lauryl sulfate, colloidal silicon dioxide

White oblong

6 pcs. in blisters

Pharmacodynamics and pharmacokinetics

The main substance inhibits the growth and reproduction of microorganisms, has a fungistatic effect and fungicidal activity, and leads to the death of fungi. Due to inhibition of ergosterol synthesis, the component combines with phospholipids of the fungal cell membrane, changing its permeability. In high concentrations, clotrimazole damages fungal cells by lysis without suppressing the synthesis of ergosterol, prevents the formation of proteins, fats and polysaccharides of fungi, destroys their nucleic acids and increases the excretion of potassium.

The drug has a broad effect on dermatophytes, yeasts, dimorphic and mold fungi, protozoa, plus it destroys gram-positive bacteria. Fungistatic activity is manifested against the mycelium of dermatophytes, budding fungi from the genus Candida. The component is practically not absorbed into the systemic bloodstream when applied to intact and non-inflamed skin. The concentration in the blood serum is insignificant; with intravaginal use, absorption is 3-10% of the dose. The drug breaks down in the liver to inactive metabolites and is excreted by the kidneys and intestines.

What is Clotrimazole ointment for?

For external use of ointment, gel, cream and solution, according to the instructions, the following indications are distinguished:

  • fungal diseases caused by dermatophytes, yeast-like fungi, mold pathogens sensitive to active component;
  • mycoses of the feet and hands;
  • candidiasis vulvitis, balanitis with localization of the fungus inside the body;
  • pityriasis versicolor, erythrasma;
  • mycosis of the skin;
  • fungal infection of the outer ear.

When using intravaginal forms of the drug (solution, suppositories and tablets), the indications are:

  • infections of the genital organs caused by yeast-like fungi of the genus Candida;
  • vulvovaginal candidiasis;
  • urogenital infections;
  • trichomoniasis;
  • genital superinfections caused by microorganisms that are sensitive to active ingredient medicines;
  • sanitation of the birth canal before childbirth.

Directions for use and dosage

The instructions and reviews say that Clotrimazole can be used vaginally or externally. The dosage, course of treatment and method of use depend on the type of disease, the individual characteristics of the patients, their age and the type of pathogen. Cream, ointment and gel are often applied to the skin to eliminate mycoses and lichens; tablets and suppositories are used intravaginally to treat urogenital candidiasis.

Clotrimazole cream

Clotrimazole cream is intended for external use. According to the instructions, it is applied to dry, clean affected areas up to three times a day. If the symptoms have already disappeared, it is recommended to continue treatment for another two weeks to prevent relapses. The cream is applied to the skin, washed with neutral acid soap, without a bandage, and used between the toes on the feet. The course of treatment is:

  • dermatomycosis – up to 4 weeks;
  • erythrasma - up to a month;
  • lichen versicolor – up to 3 weeks;
  • candidal vulvitis – up to 2 weeks;
  • minimum duration – 3 weeks.

Gel

Clotrimazole gel is also used externally on the skin. It should be used on the affected areas 2-3 times a day. According to the instructions, the minimum course of treatment will be 2-4 weeks. It is allowed to use the gel for treating the oral cavity - up to two times a day for no more than a week. If the drug is prescribed for intravaginal administration, use 100-150 mg of Clotrimazole daily for 1-6 days.

Clotrimazole ointment

According to the instructions, the ointment is applied in a thin layer 2-3 times a day to cleansed and dried skin using neutral soap. Gently rub in the mixture and leave until absorbed. Duration of therapy is:

  • dermatomycosis – from a month;
  • pityriasis versicolor – 1-3 weeks;
  • upon completion of the course, it is worth continuing treatment for another 2 weeks;
  • for fungal infections of the toenails - for 2-3 weeks.

Solution

Like the gel, Clotrimazole solution can be used externally to treat the skin and intravaginally to eliminate candidiasis pathogens. In the first case, the solution is applied to the affected dry areas up to three times a day for 0.5-1 month. To treat the mouth, rinses and applications with cotton swabs are intended twice a day for no more than a week. According to the instructions, intravaginal use of the solution should not exceed six days.

Clotrimazole suppositories

Clotrimazole suppositories are intended for topical use. According to the instructions, they are administered intravaginally by women and teenage girls. They are inserted into the vagina in the evening, very deeply, lying on your back with bent legs. The course of treatment lasts six days - during each of them one suppository is inserted into the vagina. Repeated therapy is prescribed by the doctor after examination.

Clotrimazole tablets

Another form of release for intravaginal use is tablets. The course of treatment with them lasts 6-7 days, during which one tablet per day is prescribed, or three days, one tablet twice a day. If there is no effect within three days, the diagnosis is revised, and if even after a week the treatment does not produce results, it is required medical consultation. Repeated therapy is possible, but increases the risk of detecting the pathology of diabetes mellitus or HIV infection.

If symptoms occur after a couple of months, the patient is sent to a doctor. It is allowed to combine tablets with cream if the vulva is infected. To completely dissolve the former, you need to create normal moisture in the vaginal mucosa; if it is dry, the tablet may come out. To prevent this from happening, insert the tablet as deeply as possible. According to the instructions, treatment is not carried out during menstruation. If sanitation is necessary, the woman is prescribed one tablet before giving birth.

Special instructions

According to the instructions for the types of drug, there are special instructions that must be followed when using them:

  • Avoid contact of the cream with the mucous membrane of the eyes, do not take orally.
  • Treat the infected areas at the same time, and for vaginal lesions, treat the male partner in the same way.
  • Cetearyl alcohol in the composition can cause contact dermatitis.
  • If sensitivity or skin irritation occurs, therapy is discontinued.
  • Contraceptives containing latex are destroyed by the active substance - should be used alternative drugs after five days after treatment.
  • There is no data on the effect of the drug on the speed of psychomotor reactions.
  • Control required functional state liver in patients with liver failure.

During pregnancy

The use of the drug is indicated for pregnant women only as prescribed by a doctor, if the doctor evaluates the benefit to the mother as higher than the risk to the fetus. Epidemiological studies have not revealed any disturbances in the course of pregnancy or child health when using the drug. There is no data on the effect of the drug on fertility. Suppositories are contraindicated in the first trimester of pregnancy.

In childhood

To treat fungal diseases in children, you can use Clotrimazole cream, ointment and solution. The dosage is according to the instructions, no different from adults. Vaginal tablets permitted for use from 12 years of age. Indications for use:

  • Treatment of oral candidiasis. 10-20 drops of the solution are applied to a cotton swab and wiped over the affected areas 3-4 times a day, the course lasts until the symptoms disappear completely (about 2-3 days).
  • Fungal infections of the skin, mucous membranes, nail fungus. Use cream or ointment 1-3 times/day.

Drug interactions

The instructions for use of the drug indicate its interaction with other medications:

  • Amphotericin, Nystatin and Natamycin reduce the effectiveness of Clotrimazole, except for the ointment format, which acts in the layers of the epidermis.
  • The vaginal combination of Clotrimazole and oral Tacrolimus (an immunosuppressive drug) increases the concentration of the latter in the blood plasma and requires careful monitoring of patients.

Side effects

Depending on the use of different forms of release of Clotrimazole, the following side effects are indicated in the instructions:

  • allergic reactions, urticaria, fainting, arterial hypotension, shortness of breath;
  • rash, itching on the skin, peeling, pain, swelling, irritation, burning;
  • discharge, itching, burning and swelling of the vaginal mucosa;
  • headache, stomach pain;
  • frequent urination;
  • the appearance of blisters;
  • cystitis;
  • pain during intercourse, burning sensation of the partner's penis.

Overdose

Symptoms of accidental ingestion of the drug include dizziness, vomiting, and nausea. Treatment is symptomatic. When used externally, an overdose is unlikely. When using vaginal forms of Clotrimazole in quantities exceeding the recommended, it is impossible to develop dangerous condition. If tablets or suppositories are swallowed, drowsiness, hallucinations, vomiting, and anorexia are possible. To eliminate symptoms, patients are given activated carbon. There is no specific antidote.

Contraindications

According to the instructions, contraindications for use medication are:

  • Hypersensitivity to components.
  • First trimester of pregnancy, menstruation when using suppositories.
  • The drug is used with caution during breastfeeding, in the first case of vaginal candidiasis.
  • For tablets – age up to 12 years; more than two cases of thrush in the last six months; history of sexually transmitted diseases; pregnancy; age over 60 years; hypersensitivity to imidazoles.
  • The use of tablets for bleeding from the vagina, uterine hemorrhages, ulcers, and blisters on the vulva is prohibited. They should not be used for dysuria, fever or diarrhea, vomiting, pain in the back and shoulders.

Terms of sale and storage

The cream is available in pharmacies with a prescription, other forms are available without it. Storage conditions: dry, clean place out of reach of children. Shelf life: cream, suppositories and tablets – 3 years, ointment – ​​2 years.

Analogs

According to the active substance and pharmacological action The following analogues of Clotrimazole are distinguished, produced in the form of cream, tablets, solution and suppositories:

  • Candide;
  • Kanizon;
  • Imidyl;
  • Kandibene;
  • Kanesten;
  • Ganesten;
  • Lotrimin;
  • Mycosporin;
  • Panmykol;
  • Alokandp;
  • Antifungol;
  • Dignotrimanol;
  • Faktodin;
  • Funginal;
  • Gynelotrimine.

Clotrimazole price

The cost of the drug depends on the form of its release, the seller’s markup and the manufacturer’s cost. You can buy Clotrimazole online or at your usual pharmacy. Approximate prices in Moscow are as follows.