Mezim forte (enteric-coated tablets, 20 or 80 tablets per package) Berlin-Chemie AG, Germany
If you decide to buy mezim in Volgograd, you should understand the principle of action of the drug. In general, its main substance is pancreatin, which allows you to effectively break down proteins and other products. Mezim is used in cases where there is a need to normalize digestion.
IN in this case, everything is determined individually. The doctor takes into account how serious the patients' problems are. For adults - 2 tablets at the time of eating, they do not need to be chewed, just drink with plain water.
What will be the duration of treatment? It all depends on the severity of the problem faced by the patient. Consultations with a doctor allow you to create the optimal course for taking the drug.
Pregnancy and lactation
There is not enough research to understand how safe it is to use mezim during these periods. You can use the product only after prior consultation with your doctor; he must determine the degree of risk/benefit of such actions.
Side effects
If you take the drug for too long and do not follow the dosage, then possible problems with manifestation allergic reactions. Fibrous colonation is also a possible consequence, but this phenomenon is extremely rare.
Mezim is absolutely safe means, which does not affect the reaction in any way, which is important when controlling vehicle. If a patient has pancreatitis, the doctor may prescribe the drug, but only in a strictly prescribed dosage.
Interaction
If you take folic acid, pancreatin interferes with its correct absorption, keep this in mind. Pancreatin also affects the rate of iron absorption. Products containing calcium should not be taken together with mezim; they negatively affect its global impact and do not allow the desired effect to be obtained.
Overdose
Considering the prices for Mezim Forte in pharmacies, the product is very popular among patients. If we consider the problems with possible overdose- studies have not shown any significant deviations from the norm. Among possible consequences from taking an excessive dose of the drug - constipation (mainly in children), as well as hyperuricemia. To recover from unwanted symptoms, you must stop taking the drug. Symptomatic treatment is an option.
◊ Film-coated tablets pink color, flat-cylindrical, with almost plane-parallel surfaces and beveled edges, with a characteristic odor of pancreatin.
Excipients: microcrystalline cellulose, sodium carboxymethyl starch (type A), colloidal silicon dioxide, magnesium stearate.
Shell composition: talc, hypromellose, azorubine varnish (E122), simethicone emulsion 30% (dry weight), polyacrylate dispersion 30% (dry weight), titanium dioxide (E171), macrogol 6000.
20 pcs. - blisters (1) - cardboard packs.
20 pcs. - blisters (2) - cardboard packs.
20 pcs. - blisters (4) - cardboard packs.
20 pcs. - blisters (5) - cardboard packs.
The drug compensates for the deficiency exocrine function pancreas.
The enzymes lipase, amylase and protease included in pancreatin facilitate the digestion of fats, carbohydrates and proteins, which contributes to their more complete absorption into the body. small intestine.
— insufficiency of exocrine pancreatic function (chronic, cystic fibrosis);
— chronic inflammatory-dystrophic diseases of the stomach, intestines, liver, gall bladder. Conditions after resection or irradiation of these organs, accompanied by disturbances in the digestion of food, diarrhea (as part of combination therapy);
- to improve food digestion in patients with normal function Gastrointestinal tract in case of errors in nutrition;
— preparation for x-ray and ultrasound examination of the abdominal organs.
— increased sensitivity to the components of the drug;
- acute pancreatitis;
- exacerbation chronic pancreatitis.
The dose is determined individually depending on the degree of digestive disturbance.
For adults: 1-2 tablets each. before meals, without chewing and with water. If necessary, take another 1-4 tablets with meals.
U children the drug is used as prescribed by a doctor.
The duration of treatment can vary from several days (if the digestive process is disrupted due to errors in the diet) to several months or years (if constant replacement therapy is necessary).
In isolated cases, patients suffering from cystic fibrosis experience the formation of strictures in the ileocecal region after taking high doses.
With the simultaneous use of pancreatin with iron preparations, the absorption of the latter may be reduced.
The simultaneous use of antacids containing calcium carbonate and/or magnesium hydroxide may lead to a decrease in the effectiveness of pancreatin.
Mezim is a medicine that contains digestive enzymes. The drug promotes not only the proper breakdown of fats, proteins and carbohydrates, but also their absorption. With an unbalanced diet, dyspeptic symptoms often occur, which Mezim helps with even after a single dose. Despite the over-the-counter availability of the drug, gastroenterologists do not recommend its use without prior examination gastrointestinal tract. The fact is that the cause of indigestion is both banal overeating and serious illnesses.
Mezim is a pharmacological drug intended for the treatment of digestive disorders
Due to the presence of several enzymatic substances in its composition, Mezim is used in the treatment of almost all diseases that are accompanied by digestive disorders. Diarrhea and bloating due to increased gas production can occur for various reasons:
Mezim is used to reduce the severity or completely eliminate symptoms of both maldigestion and malabsorption. Includes pancreatin containing:
Active ingredient The drug is enclosed in a durable shell that even caustic hydrochloric acid cannot destroy. Mezim easily penetrates the small intestine, where pancreatin is released. There are several types of medicine:
They differ from each other in the amount of active ingredient, the appearance of the packages and even the color of the tablets. Daily and single dosages, as well as duration course treatment can be determined by a gastroenterologist. It focuses on the results of laboratory and instrumental studies, takes into account general condition human health, history of diseases.
When overeating or consuming spicy, fatty, fried foods, gastroenterologists recommend Mezim Forte, which contains the smallest amount of active ingredient, to patients. But doctors warn against its frequent use due to the development of addiction. In such cases, the pancreas simply begins to be “lazy” and produce its own enzymes. After stopping taking Mezim, a person may experience serious problems with the digestion of food.
Mezim 10000 and Mezim 20000 help with dyspeptic disorders accompanying serious diseases. When malabsorption is diagnosed in patients, in the vast majority of cases such drugs are prescribed to patients for life. In combination with a gentle diet, this allows a person not to experience the painful symptoms of flatulence. Also, disruption of the gastrointestinal tract can occur in the following cases:
All these factors that provoke digestive disorders cannot be eliminated only by taking Mezim. Diseases such as cholecystitis or pancreatitis require integrated approach to treatment. But gastroenterologists always include in the therapeutic regimen drugs that reduce the severity of dyspepsia symptoms. Doctors prescribe Mezim to patients for flatulence that occurs against the background of all pathologies of the pancreas and gallbladder.
When using Mezim in the treatment of children, you need to remember that the tablet cannot be crushed or dissolved in water
Mezim is a medicine intended for the treatment of various pathologies and for the prevention of digestive disorders. Gastroenterologists recommend taking the drug before an upcoming celebration, where food that is heavy for the stomach is expected. Mezim will help quickly break down fats and carbohydrates and avoid indigestion. But the main area of use of the drug is to alleviate the human condition with organ diseases digestive tract. These include:
Digestive disorders are often diagnosed in young children. Natural curiosity and restlessness help them explore the world, and for parents they become a source of anxiety and worry. Unwashed fruit straight from the tree, berries freshly picked from the bush are put into the mouth with hands that have recently been stroked stray cat or a dog. It is not surprising that after a couple of days the child develops an intestinal infection. Children suffer from the following symptoms:
Usage pharmacological drug helps normalize the functioning of the gastrointestinal tract when taken simultaneously with drugs that destroy pathogens intestinal infections. Mezim for bloating in young children is also prescribed after eating fatty and fried foods.
Advice: “Parents should take into account one feature - when giving a child a tablet, it cannot be divided or dissolved in water. The active substance must penetrate the intestines, so the drug shell cannot be damaged.”
Digestive disorders can be treated with Mezim during pregnancy only if you follow a gentle diet.
Heartburn, bloating, increased gas formation- frequent companions of a pregnant woman. At this time, numerous changes occur in her body aimed at fully bearing the baby. Digestive disorders may result from changes in hormonal levels. But the main reason for disruption of the gastrointestinal tract is the growing uterus. She squeezes internal organs, interfering with the normal processes of food digestion.
Recommendation: “You can avoid the symptoms of flatulence during pregnancy without taking medications. A woman should avoid eating foods that cause fermentation and putrefaction in the stomach and intestines. These include all legumes, whole milk, and sweet pastries.”
The annotation attached to Mezim Forte does not prohibit the use of tablets for pregnant women and women breastfeeding. But manufacturers warn that the question of using the drug should be decided by a doctor. He will correlate:
As a rule, Mezim is prescribed to pregnant women only in case of serious dysfunction:
That is, for diseases associated with insufficient production enzymes or their improper absorption. A deficiency of nutrients and biologically active substances will negatively affect the development of the child, therefore in all these cases Mezim is recommended for use. But if you overeat or consume foods with high content fats and carbohydrates, if the drug is prescribed, it is only once. Gynecologists and gastroenterologists advise women to exclude such dishes from their daily diet while pregnant.
Pills
; Pancreatin 137.5 mg, with minimal enzymatic activity: lipase 10,000 units Ph.Eur, amylase 7500 units Ph.Eur, protease 375 units Ph.Eur. Excipients: lactose monohydrate, microcrystalline cellulose, colloidal silicon dioxide, crospovidone, magnesium stearate. ; Shell composition: hypromellose, copolymer of methacrylic acid and ethyl acrylate (1:1) dispersion 30% (dry weight), triethyl citrate, titanium dioxide (E171), talc, simethicone emulsion 30% (dry weight), macrogol 6000, carmellose sodium, polysorbate 80 , azorubine varnish (E122), sodium hydroxide.
;An enzyme preparation that improves digestion. Pancreatin is a powder from pork pancreas, which, along with exocrine pancreatic enzymes - lipase, amylase, protease, trypsin and chymotrypsin, also contains other enzymes. Pancreatic enzymes included in the drug facilitate the breakdown of proteins, fats and carbohydrates, which leads to their more complete absorption into the body. small intestine. Trypsin suppresses stimulated pancreatic secretion, producing an analgesic effect. The maximum enzymatic activity of the drug is observed 30-45 minutes after oral administration.
;Mezim forte 10000 tablets are coated with an acid-resistant coating, which does not dissolve under the action of hydrochloric acid of the stomach and thereby protects the enzymes contained in the drug from inactivation. Dissolution of the shell and release of enzymes occurs at a pH value close to neutral or slightly alkaline.
Replacement therapy at exocrine insufficiency functions of the pancreas (including chronic pancreatitis, cystic fibrosis) - chronic inflammatory-dystrophic diseases of the stomach, intestines, liver, gall bladder - conditions after resection or irradiation of the gastrointestinal tract, accompanied by impaired digestion of food, flatulence, diarrhea (as part of combination therapy ) - gastrointestinal disorder of a functional nature (with intestinal infectious diseases, irritable bowel syndrome, etc.) - to improve food digestion in patients with normal gastrointestinal function in case of errors in nutrition - preparation to X-ray and ultrasound examinations abdominal organs.
;- acute pancreatitis; - exacerbation of chronic pancreatitis; - hypersensitivity to pancreatin or other components of the drug; - hereditary intolerance galactose, lactase deficiency or glucose-galactose malabsorption syndrome; - childhood up to 3 years (indivisible dosage form).
;Due to the lack of sufficient data on the use of pancreatic enzymes in humans during pregnancy and lactation, the use of Mezim Forte 10000 is possible only if the expected benefit to the mother outweighs the possible risk to the fetus or child.
;The dose of the drug Mezim forte 10000 is set individually depending on the severity of the disease and the composition of the food. Unless otherwise indicated, medium single dose for adults is 2-4 tablets. Mezim forte 10,000 per meal. It is recommended to take half or a third of a single dose at the beginning of a meal, and the rest during it. The drug is taken orally, without chewing and with a sufficient amount of liquid. It is possible to increase the dose, which should only be done under the supervision of a physician, focusing on reducing symptoms (for example, steatorrhea, abdominal pain). The maximum daily dose is 15,000-20,000 units Ph.Eur. lipase/kg body weight. For children, the dosage regimen is determined by the doctor depending on the severity of the disease and the composition of the food at the rate of 500-1000 units Ph.Eur. lipase/kg of child's body weight for each meal. The duration of treatment can vary from several days (for indigestion, dietary errors) to several months and even years (if constant replacement therapy is necessary).
;No development detected side effects or complications even with long-term and regular use of the drug Mezim forte 10000 in patients with impaired pancreatic function. In some cases, after taking pancreatin, allergic reactions may develop; rarely - diarrhea or constipation, nausea, discomfort in the epigastric region. In isolated cases, in patients suffering from cystic fibrosis, with long-term use high doses of the drug may develop hyperuricosuria (increased levels uric acid in blood plasma), the formation of strictures in the ileocecal region and the ascending colon is possible.
;There are no data on cases of overdose and intoxication with the drug. Possible: hyperuricosuria. hyperuricemia, in children - constipation. Treatment: drug withdrawal, symptomatic therapy.
;When taking medications containing pancreatin, absorption may be reduced folic acid. Action hypoglycemic drugs(acarbose, miglitol) may decrease when taken simultaneously with pancreatin. With the simultaneous use of pancreatin with iron preparations, the absorption of the latter may be reduced. The simultaneous use of antacids containing calcium carbonate and/or magnesium hydroxide may lead to a decrease in the effectiveness of the drug.
;At acute pancreatitis or exacerbation of chronic pancreatitis (at the stage of attenuation of exacerbation), during recovery dietary nutrition, it is advisable to prescribe Mezim forte 10000 against the background of existing or remaining pancreatic insufficiency. Mezim forte 10000, taking into account the solid indivisible dosage form, is contraindicated in children under 3 years of age. Effect of the drug on the ability to drive vehicles and operate machinery: Mezim forte 10000 does not affect the speed of psychomotor reactions and the ability to perceive or assess a situation.
Content
By medical classification, Mezim Forte is an enzyme-based drug, the use of which is aimed at replenishing the deficiency of enzymatic activity of the digestive tract. The composition of Mezym Forte, produced by the German manufacturing company Berlin-Chemie, includes pancreatin obtained from the pancreas of pigs. Read the instructions for use of the medication.
Mezim Forte is presented in three tablet formats: regular, 10,000 and 20,000. Their differences are in the composition:
|
Mezim Forte |
Mezim Forte 10000 |
Mezim Forte 20000 |
|
|
Description |
Pink pills |
Pink round tablets |
White-grayish round tablets |
|
Minimum enzymatic activity of lipase, units. per piece |
|||
|
Amylase activity, units per piece |
|||
|
Protease activity, units per piece |
|||
|
Additional components |
Macrogol, microcrystalline cellulose, titanium dioxide, sodium carboxymethyl starch, polyacrylate dispersion, colloidal silicon dioxide, simethicone emulsion, magnesium stearate, azorubic varnish, hypromellose, talc, starch glycolate, polyethylene glycol |
Sodium hydroxide, lactose monohydrate, azorubic lacquer, microcrystalline cellulose, carmellose sodium, colloidal silicon dioxide, polysorbate, crospovidone, macrogol, magnesium stearate, simethicone emulsion, hypromellose, talc, methacrylic acid-ethyl acrylate dispersion, titanium dioxide, triethyl citrate |
Bergamot flavor, lactose monohydrate, vanilla flavor, microcrystalline cellulose, polysorbate, colloidal silicon dioxide, carmellose sodium, crosspovidone, macrogol, magnesium stearate, simethicone emulsion, hypromellose, talc, methacrylic acid-ethyl acrylate copolymer, titanium dioxide, triethyl citrate |
|
Package |
Blisters of 20 pcs., packs of 1, 2, 4 or 5 blisters |
Blisters of 10 pcs., packs of 1 or 2 blisters |
Blisters of 10 pcs. packs of 1, 2 or 5 blisters |
The use of the drug is intended to compensate for the insufficient activity of the pancreas. The active component of the composition is pancreatin, consisting of the enzymes lipase, protease and amylase. They improve the absorption of carbohydrates, proteins and fats in the small intestine. In addition to these enzymes, pancreatin, obtained from porcine pancreas powder, contains trypsin and chymotrypsin.
Trypsin suppresses pancreatic secretion and has an analgesic effect. The maximum activity of the drug during transit appears 30–45 minutes after taking the tablets. Unlike Mezim Forte, preparations with the prefix 10000 or 2000 contain more enzymes and have a special coating that is resistant to hydrochloric acid, which protects the enzymes it contains from inactivation, dissolves in an alkaline environment.
The instructions for use of the drug highlight a number of indications for use. These include:
Instructions for use of Mezim Forte differ for different types of the drug. So, the tablets cannot be divided or bitten, because otherwise the activity of the enzymes will be impaired. All tablets are taken orally with a glass of water. The dosage and course of treatment with the medication are determined by the attending physician based on the patient’s condition and medical history.
For adult patients, the instructions suggest taking 1–2 tablets. before eating. They cannot be chewed, they must be washed down with water. If your doctor prescribes it, you can take another 1–4 tablets with food. For children, the dosage of the drug is prescribed by the doctor. The duration of medication treatment can last from several days (with errors in nutrition) to several months (with constant replacement therapy).
A single dose of medication for adults is 2–4 tablets. Half or a third of the indicated dose is taken before meals, the rest - during it. The tablets cannot be chewed; they must be taken with liquid. If the symptoms weaken, abdominal pain appears, the dosage may be increased, but not higher than 15–20 thousand units of lipase per kilogram of body weight. For children, the dose is calculated as 500-1000 units of lipase per kilogram of weight. According to the instructions, the course of treatment lasts from several days to months, depending on the disease.
In the absence of other instructions, the instructions for use contain information about adult dosage the drug in the amount of 1-2 tablets with meals. The drug is not chewed, washed down with a glass of water. Cannot exceed daily dose 15–20 thousand units of lipase per kilogram of body weight. For children, the dosage is calculated as 1000 units of lipase per kilogram of weight. The course lasts from a couple of days to several weeks.
The use of medications does not affect the decrease in concentration or speed of psychomotor reactions. The instructions indicate that the product contains active enzymes, which, when biting into tablets, can lead to ulceration of the mucous membrane. If patients with cystic fibrosis develop symptoms while taking Mezim intestinal obstruction, it is necessary to be examined for possible intestinal strictures. The use of the drug is contraindicated in case of galactose intolerance, lactase deficiency, or impaired absorption of galactose-glucose.
According to the instructions, the safety of using pancreatin during pregnancy and breastfeeding. Doctors can prescribe Mezim, but only if the benefit to the mother exceeds the risk to the fetus or newborn baby. You should use the tablets with caution during pregnancy and lactation, and do not exceed the permissible dose.
Medicine can be given to children only as prescribed by a doctor. The drugs Mezim Forte 10000 and 20000 are contraindicated under the age of three years, since their dosage form is solid, indivisible, children are unable to swallow the tablet. The dosage regimen for children is set by the doctor at the rate of 500-1000 units of lipase per kilogram of body weight with each meal. Do not chew the tablets.
The standard pediatric dosage is 1-2 tablets with meals. Up to 12 years of age, the dose is prescribed in the amount necessary to normalize bowel movements - not more than 1500 units of lipase per kilogram of body weight. For teenagers 12-18 years old, the instructions prescribe to take no more than 15-20 thousand units of lipase per kilogram of weight. Mezim 20000 is taken at the rate of 1000 units of lipase per kilogram of body weight.
The combination of pancreatin with iron preparations leads to a decrease in the absorption of the latter. Others drug interactions Mezima from the instructions:
While taking Mezim tablets, unwanted side effects may develop. The instructions highlight the following:
To date, there is no data on cases of drug overdose. The instructions contain information that if the dose taken is exceeded or long-term use increased amount tablets, the development of hyperuricosuria, hyperuricemia, and constipation in children is possible. To treat the consequences of an overdose, the drug is discontinued and symptomatic therapy is carried out. There is no antidote.
The drug is dispensed from pharmacies without a prescription and is stored at a temperature not exceeding 30 degrees for three years from the date of manufacture.
The drug can be replaced medicines with a similar effect, containing pancreatin or other enzymes. These include:
Mezim Forte can be purchased via the Internet or pharmacy chains. The cost of the product depends on the form of release, packaging volume, and trade margin. Approximate Moscow prices.
