The drug is a competitive antagonist of the mineralocorticoid aldesterone. The medicine is prescribed for liver cirrhosis, heart failure, blood pressure, acne, hyperandrogenism, high testosterone and other ailments. The dosage depends on the nature of the disease and is prescribed individually. The instructions for use explain in detail how to take the tablets and what they help with. Wikipedia defines the drug as a potassium-sparing diuretic. The international name by international name is Spironolactone (in Latin). Acts as a diuretic.
The purpose of the drug is determined by its diuretic effect. The drug has the following indications: adrenal adenoma, primary hyperaldosteronism, edema during pregnancy, hirsutism during polycystic disease, liver damage, nephrotic syndrome. The product is widely used for edema. Women take pills for menstruation and for weight loss.
The active ingredient of the drug is spironolactone. In addition, the composition includes magnesium stearate, colloidal silicon dioxide, corn starch, lactose monohydrate. The capsules contain sodium lauryl sulfate. The gelatin capsule consists of quinoline dye, gelatin and titanium dioxide.
The duration of taking the drug depends on the diagnosis. So, for essential hypertension, the medicine must be taken for at least two weeks, and the daily dosage should be from 50 to 100 mg. To treat primary hyperaldosteronism, tablets should be taken for four days at 400 mg per day. During long-term diagnostic tests, the medicine is taken for three to four weeks.
The pharmacological group contains other analogues of the drug. Such agents as furosemide, indapamide, diuver, veroshpilactone, prolactin, triampur and others are widely used. Funds are available in Ukraine, Perm, St. Petersburg, Omsk and other cities of the Russian Federation.
In this matter, everything depends on the goals pursued by the patient. Furosemide is a cheaper analogue of veroshpiron. It helps remove fluid from the body, but only veroshpiron has a potassium-sparing mechanism. Therefore, questions about choice should be decided individually.
According to cardiologists, the first drug is best taken to prevent heart failure. It is preferable to take Diuver for the direct treatment of this pathology. In any case, before replacing one medicine with another, consult your doctor, as the difference between taking them can be significant.
When a diagnosis of hyperaldosteronism is made, the drug is recommended in a dosage of 100 to 400 mg per day, one to four times a day. In other cases, the medicine is taken orally at 0.05 - 0.3 grams per day. The dose is usually divided into two to four doses. If the patient's condition has improved, then the dose is reduced to 0.025 g per day. People suffering from Parkinson's syndrome are prescribed twenty-day courses with breaks of five months. For hypertension, the medicine is prescribed at 0.025 g. four times a day.
Teenagers can obtain and take medication in any form only with a prescription.
During edema that occurs with nephrotic syndrome, the adult dose is 100 to 200 mg per day. Edema syndromes in heart failure are treated with doses of one hundred and two hundred mg per day for five days. Edema in liver cirrhosis is relieved with a daily dosage of 100 mg. To relieve edema in children, the dose is from 1 to 3.3 mg per kilogram of the child’s weight. After 5 days, the dosage is adjusted.
When planning pregnancy and during fetal development, taking the drug is contraindicated. In addition, the medicine should not be taken during lactation or while breastfeeding. If therapy with veroshpiron is necessary, breastfeeding should be stopped.
The drug is indicated in gynecology to reduce androgens in women suffering from polycystic ovary syndrome. The medicine can cause bleeding and disrupt the menstrual cycle. It is better to take the pills together with contraceptives.
This drug is officially prohibited for newborns and children under three years of age. However, in some cases, the attending physician may prescribe medication in an inpatient setting.
In professional circles and among patients, reviews of the drug are positive character. Contraindications for women: hypersensitivity, renal failure and diabetic nephropathy. Compatibility with alcohol is negative.
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Polycystic ovary syndrome (PCOS) is a disease of the female reproductive system, which is characterized by impaired production of female sex hormones, an increase in the size of the ovaries with the appearance of cysts, menstrual disorder, infertility and other symptoms.
Normally, the ovaries are two almond-shaped glands that contain follicles - small sacs containing eggs. Under the influence coordinated work In the hormonal system, about 20 follicles begin to mature monthly. Mostly, only one follicle containing the egg fully matures, filling with fluid. An enlarging follicle appears as a small cyst on the surface of the ovary, which can be seen on an ultrasound.
Then, under the influence of the hormones FSH and LH, the follicle ruptures - ovulation - and the egg is released. The cells lining the ruptured follicle begin to produce the hormone diferelin, Androcur, etc. These drugs block the action of androgens, in addition, they help establish a normal menstrual cycle. These medications are taken on certain days of the menstrual cycle - the treatment regimen is prescribed by the attending physician.
Treatment of polycystic ovaries for infertility
The initial stage of treatment for polycystic ovaries in case of infertility in women is weight loss (if overweight) and, in the presence of carbohydrate metabolism disorders (insulin resistance), taking the drug Metformin.
If such treatment is insufficient, ovulation is stimulated by Gonal-F). Treatment regimens are determined by the doctor individually.
Women with polycystic ovary syndrome who want to get pregnant are also prescribed progesterone in the second phase of the cycle, the dosage is determined by the doctor. At the same time, regular menstruation is restored and stops. uterine bleeding and excess growth of the endometrium inside the uterus. However, progesterone does not help cleanse the skin.
Surgical treatment of polycystic ovaries (PCOS)
In rare cases, ovulation cannot be achieved with medication. Then apply surgical methods treatment of polycystic ovaries. The main methods of surgical treatment of infertility in polycystic ovaries are: wedge resection of the ovaries and electrocautery of the ovaries.
Wedge resection of the ovaries is an operation that is performed using a laparoscope (through small incisions in the abdomen) under general anesthesia. This involves removing a section of ovarian tissue that produces excess hormones. Reducing excessive hormone production after surgery helps normalize the menstrual cycle, promote ovulation, and make pregnancy possible. However, such surgical intervention in the future can lead to negative consequences for the reproductive system, causing the formation of adhesions and a decrease in the follicular reserve of the ovaries.
Electrocautery of the ovaries is a laparoscopic operation performed under general anesthesia. During electrocautery, a special instrument produces a targeted destruction of the part of the ovary that produces excess hormones. This operation is more gentle.
As a rule, surgical treatment polycystic ovaries leads to the possibility of conceiving a child within the next 6-12 months.
An effective method of treating infertility in PCOS is in vitro fertilization.
Veroshpiron - diuretic, designed to increase diuresis in the treatment of many diseases, which also has a potassium-sparing property, rare for diuretics. The effect of taking veroshpiron lasts up to several days, and the medicine itself is well tolerated by most patients.
The drug Veroshpiron has a pronounced diuretic effect due to spironolactone, an analogue of the hormone produced by the adrenal cortex. Spironolactone in turn suppresses the hormone aldosterone, preventing the retention of water and sodium in the renal tubules. At the same time, Veroshpiron does not impair renal blood circulation, reduces the acidity of urine and reduces the leaching of potassium from the body.
The latter property of the drug is very valuable and rare for diuretics, so Veroshpiron is also prescribed in cases where the patient is prone to hypokalemia.
When using Veroshpiron:
Verospiron is produced by the Hungarian company Gedeon Richter exclusively in the form of tablets or capsules. The tablet form is available in blisters of 20 pieces of 25 mg each, and capsules are produced in blisters of 20 pieces of 50 mg each and in blisters of 10 pieces of 100 mg each. The tablets have a chamfer and the inscription VEROSPIRON, and the capsules are enclosed in a two-color gelatin case.
The international nonproprietary name (INN) of the diuretic is spironolactone, based on the name of the active substance.
The price of the drug and its analogues is approximately the same and currently remains at the level of 100-250 rubles per package of 20 tablets or capsules.
When taking the drug, it is rapidly absorbed in the gastrointestinal tract, and this process is not affected by food intake and Veroshpiron can be taken both before and after meals.
Although the bioavailability of the drug is almost 100%, the maximum effect of the drug develops on the 2nd or 3rd day of administration and lasts up to 3 days after its discontinuation. During the biotransformation of spironolactone in the liver, metabolites containing sulfur are formed: alpha-thiomethylspironolactone and canrenone. Decomposition products are excreted in urine and partially in feces.
The main purpose of Veroshpiron as a diuretic drug is to reduce fluid levels in arterial hypertension (high blood pressure), but in addition, the drug is used for:
Veroshpiron should not be combined with a number of other medications:
Spironolactone also enhances the effectiveness of other diuretics and antihypertensive drugs.
In most cases, Veroshpiron is used in combination with other medications, but sometimes monotherapy is prescribed, especially as a diuretic.
The main purpose of the drug is a diuretic. However, due to the multiple properties of spironolactone, this medicine is also used to treat other diseases.
The drug Veroshpiron, along with a purely diuretic effect, has antiandrogynous properties and therefore is successfully used in the composition complex therapy gynecological pathologies.
The medicine acts in organs that produce male hormones (including follicles, sebaceous and sex glands), reduces hair growth skin with hyperandrogenism and ultimately helps improve female fertility.
It is important that treatment of women with Veroshpiron does not cause side symptoms. endocrine system.
The drug Veroshpiron is prescribed in gynecology most often for the following diseases:
A pathology in which a woman’s body actively produces androgen, which is largely considered masculine. Increased production of this hormone by the female body leads to disruption of hormonal levels and the synthesis of the hormone tarragon, which is responsible for libido. This pathology It occurs quite often - about 5% of women are susceptible to it.
Treatment is carried out with glucocorticosteroids, or non-steroidal antiandrogens (flutamide), with additional prescription nootropic drugs and Veroshpiron. In case of hyperandrogenism, Veroshpiron works not only as a diuretic, but also as a suppressor of testosterone, converting it into estradiol, and normalizing the condition of the skin. Treatment of this pathology is long-term, at least 3-6 months, while spironolactone is prescribed according to the schedule (according to the menstrual cycle), at a dosage of 100 mg/day, increasing the tablet intake if necessary to 400 mg/day.
Pathology of the ovaries, which is associated with disruption of their functioning resulting from neurometabolic disorders. In other words, this is a disease in which multiple cysts form on the surface of the organ itself - the ovary. This syndrome often leads to infertility.
Veroshpiron in the treatment of polycystic disease is prescribed to block male sex hormones, 100 mg 2-4 times a day, for up to six months. Therapy for polycystic disease should be comprehensive, since Veroshpiron only eliminates the external manifestations of the disease (oily skin, hair growth, etc.).
Interestingly, the symptoms of the disease disappear in women along with the normalization of weight, if it is elevated or excessive.
One of the indicators of changes in the functioning of both the genital organs and the entire female body. In general, disruption of the menstrual cycle is one of the most common problems with which women of reproductive age turn to a gynecologist. The disorder may be caused for various reasons, which only the attending physician can help determine. If he deems it necessary to add Veroshpiron to therapy, the drug is prescribed in the first phase of the menstrual cycle, at a dosage of 50 mg/day. Combine spironolactone with oral contraceptives(not for the purpose of contraception, but to normalize the body’s hormonal levels).
Excessive hair growth on the body of women according to the male pattern - female disease associated with disruption of the normal functioning of the endocrine system: manifests itself through excessive hair growth on the body or face. Also, along with these syndromes, such syndromes as menstrual irregularities, anemia appear, uterine bleeding and infertility are possible.
For hirsutism, Veroshpiron can be taken according to two regimens: either from the 4th to the 22nd day of the cycle, in a dosage of up to 200 mg, or outside of the cycle, 75-100 mg daily. Moreover, after 3-6 months of treatment, the symptoms of hirsutism decrease by an average of 30%, which is good result.
A disease such as hypertension is itself a disease cardiovascular system, characterized by a stable increase in pressure, the levels of which decrease only after taking medications. A common occurrence is swelling of the hands, feet or face, which occurs due to sodium and water retention in the body. Spironolactone is used in this case because of its diuretic properties. The dosage and regimen are determined by the doctor, based on the severity of the disease.
Indications for the use of Veroshpiron may include the presence of certain cosmetic problems in women caused by an excess of male hormones in the body. These problems include:
Most of these problems are due to the fact that hair follicles, as well as sebaceous glands, depend on the normal production of androgen hormones and respond to an increase in their levels in the female body. It is not recommended to use the drug for weight loss, as this is fraught with dehydration, disruption of the endocrine system and other complications.
When treating cosmetic imperfections, Veroshpiron also acts as a blocker of male sex hormones, and to normalize the hormonal levels of women, oral contraceptives are added to it.
Important: Veroshpiron should not be used during pregnancy (existing or planned), since in this case there is a high risk of developing fetal abnormalities.
Just like anyone else medication, the diuretic Veroshpiron has a number of contraindications. These include a number of diseases for which the use of spironolactone is completely prohibited, as well as diseases for which the use of products containing spironolactone is recommended with extreme caution. It is better to replace Veroshpiron with a drug similar in action to it in the presence of pathologies such as:
A complete list of diseases for which the use of Veroshpiron is not recommended is given in the instructions for use of the drug.
It is important to remember that taking diuretics is prohibited for children under the age of three years old, as well as people who have hypersensitivity to the components that make up the drug. It is prohibited to take Veroshpiron for Addison's disease ( chronic failure adrenal cortex) and in severe renal failure.
Under no circumstances should a diuretic be used during pregnancy or lactation, however, if treatment is necessary and directly prescribed by a doctor, the drug prescribed to eliminate edema can be used with caution during pregnancy - in the second and third trimester.
The active substance spironolactone, which is the basis of the drug Veroshpiron, is contraindicated during pregnancy because it can penetrate the placental barrier. In this case, the drug goes directly into the children's circulatory system.
It is also not recommended to use Veroshpiron during breastfeeding due to the high activity of the main ingredient, which is absorbed into all biological fluids of the body, reaching almost full concentration.
Veroshpiron can also be used with caution for such disorders and diseases as:
Particular attention should be paid to the patient’s age, the presence of diabetes mellitus, as well as his recent history of surgical interventions.
Most of the side effects of the drug Veroshpiron can be attributed to the so-called “traditional”:
More specific side effects usually include digestive disorders:
Disturbances in the functioning of the muscular system:
Metabolic disorders such as a decrease in the level of sodium in the blood and the level of urea contained in the blood are also possible, uric acid and creatinine. It is impossible to completely protect yourself from side symptoms when treating with Veroshpiron, as with any other medicine.
If unpleasant symptoms do not go away 2-3 days after starting to take the medication, you should notify your doctor to decide on replacing the drug or adjusting the dose taken.
If it is not possible to purchase Veroshpiron, you can replace it with tablets with the same active substance. Veroshpiron and its analogues act almost identically.
The following drugs can replace Veroshpiron:
The main substance in these drugs is also spironolactone, sometimes with a combination of another drug. Thus, Aldactone retains not only potassium, but also magnesium in the body, and Veroshpilaktone combines the properties of Veroshpilaktone and Aldactone.
Veroshpiron for gynecological diseases, thanks to its diuretic and antiandrogynous actions, helps with wide range pathologies.
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After making a diagnosis, the doctor, based on the clinical picture and ultrasound features, will determine how to treat PCOS in your case. When treating, it is not always possible to resort to surgery using a complex of drugs. Although, if medications do not provide progress over 6-12 months, laparoscopic treatment may be recommended.
Treatment of this pathology involves an integrated approach. This includes not only medications or surgery, but also lifestyle changes. Often, these measures help almost as well as therapeutic ones. First of all, you need to improve your physical activity and critically reconsider nutrition, especially given the tendency to obesity as one of the symptoms of PCOS. It is necessary to play sports or fitness, follow a diet with a limit on “light” carbohydrates (sugar, sweets) and an increase in the amount of protein and plant food. It is important not to starve, but to reduce the calorie content of food consumed so that the weight comes off smoothly and evenly, without fluctuations in blood sugar. Often, weight loss significantly increases the effects of medications, and after stabilizing the weight, the desired pregnancy quickly occurs.
One of the main questions is: can PCOS be cured? By carefully following the doctor’s recommendations and carrying out all procedures, it is often possible to overcome all barriers to pregnancy. Many of those who suffered from polycystic disease, after successful treatment and the birth of the first child mark the normalization of hormonal levels and the disappearance of PCOS.
What is used in therapy for PCOS? Treatment includes several groups of drugs. To normalize carbohydrate metabolism and increase tissue sensitivity to insulin, PCOS treatment with metformin is used. This drug restores metabolic disorders, and the use of metformin for PCOS can lead to normalization of glucose and carbohydrate metabolism, weight stabilization, and normalization of the concentration of male sex hormones. All this ultimately leads to normalization of ovarian function and restoration of ovulation. If the body is insensitive to metformin, a regimen of glucophage is often used for PCOS. Its action is similar to the previous drug.
Metypred can also be prescribed for PCOS. It is used to suppress the activity of male sex hormones and normalize the functioning of the adrenal glands. It is taken strictly under the control of an ultrasound picture of the condition of the ovaries. In addition to therapy, cyclodinone may be prescribed for PCOS. This is a drug from the group of dietary supplements that helps normalize the menstrual cycle. Data on its effectiveness vary. However, it is worth remembering that this drug does not treat PCOS, it only has an additional effect and is used in combination with other drugs.
In order to stabilize hormonal background and normalize the menstrual cycle against the background of polycystic disease, treatment regimens are used hormonal drugs. Usually special COCs are prescribed (tablets for combination oral contraception). Drugs are selected that contain special anti-androgenic components. These substances block the formation and effect of male sex hormones on tissue. While taking COCs, the ovaries are unloaded, they can “rest” and normalize their structure. This regimen helps in treatment and stops the progression of PCOS. When these drugs are discontinued, ovulation often occurs, and pregnancy occurs in the first months after treatment.
If, after a course of contraceptives, the functioning of the ovaries is not fully restored, they resort to stimulating ovulation with the help of special drugs. They begin their administration with a small dose, gradually increasing it. Ovulation is monitored by ultrasound, measuring the size of the follicles.
Against the background of ovarian stimulation, PCOS treatment with duphaston is used for support. This is a preparation of progesterone, which is necessary during the menstrual cycle for the egg to mature, ovulation and conception to occur. It also supports implantation, early development embryo. If there is a deficiency of progesterone, which often happens with PCOS, even if conception has taken place, pregnancy failure may occur. This cannot be allowed.
In order to correct the level of angrogens (male hormones in the blood), veroshpiron can be additionally prescribed. In addition to normalizing hormonal levels, it gives a slight diuretic effect, reduces the formation of acne and oily skin, and helps hair growth.
You can often find recipes on the Internet for treating PCOS with boron uterus. These methods of therapy must be taken very critically, since this herbal remedy does not have hormonal activity. It can only be used in combination with other drugs; taking only decoctions or infusions of this plant will be useless.
If ineffective drug treatment PCOS can be treated with laparoscopic surgery. It is performed through small incisions in the abdominal cavity using special instruments under general anesthesia. In this case, on the surface of the ovaries, covered with a dense membrane, incisions are made (wedge resection method) or holes (diathermocauterization), through which eggs can leave the ovary during ovulation. After such an operation, the effect lasts for 9-12 months, which makes it possible to get pregnant.
Often it is the operation that leads to the fact that ovulation finally occurs and the desired pregnancy occurs.
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The drug Veroshpiron has already been used in gynecology for a long time famous high efficiency and positive properties. It is aimed at removing excess liquid from fabrics. Its advantage is that (unlike other diuretics) Veroshpiron does not flush out chlorine, potassium and sodium from the body, but only enhances their accumulation. Usually this effect is noticeable already on the fifth day of use.
Indications for use in gynecology: irregular menstruation, hyperandrogenism, increased hair growth, polycystic ovary syndrome,
Cosmetic problems caused by excess quantity male hormones (acne, hair loss, oily skin).
From everything written above, it becomes clear that this drug It also has antiandrogenic properties. Its effect is manifested in a decrease in the intensity of hair growth in patients with hyperandrogenism. Also during its use there are no side effects from the endocrine system.
Contraindications: 1) individual intolerance to the components, 2) breastfeeding and pregnancy, 3) hyponatremia and hyperkalemia, 4) renal failure, 5) excess calcium, 6) planning surgical interventions, 7) diabetes mellitus, 8) old age.
In most cases, taking the drug is accompanied by complications: drowsiness, diarrhea, vomiting, constipation, liver problems, calf muscle cramps, allergies, painful sensations in the area of the mammary glands, menstrual irregularities,
Changes in laboratory parameters.
It is necessary that the duration of administration, dosage and the necessary phase of the cycle suitable for treatment are strictly prescribed by the treating gynecologist, depending on the severity of the disease, type, as well as the individual characteristics of the body. Sometimes, as a preventive measure for menstrual irregularities, Veroshpiron is recommended in gynecology to be taken together with oral contraceptives.
While taking this medical product It is prohibited: a) to eat foods high in potassium (prunes, apricots, bananas and tomatoes), b) to drink alcoholic drinks, c) perform actions that require increased attention.
Inna, 25 years old: “A year ago I was diagnosed with polycystic disease, plus my testosterone level was almost doubled. After taking veroshpiron tablets, the hormonal levels were restored, and everything was fine on the ultrasound. There is only one conclusion: it really helps.”
Yulia, 31 years old: “My doctor recommended this remedy to me after I complained that I was getting very full before menstruation. I took the course and noticed that there was no more swelling.”
Alla, 21 years old: “Veroshpiron helped me restore my menstrual cycle. I was also pleasantly surprised to find that my skin gradually began to clear up and my pimples and blackheads disappeared.”
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Veroshpiron is a popular medicine prescribed for severe hypertension that does not respond to conventional treatment, as well as for edema in heart failure and cirrhosis of the liver. Women take Veroshpiron to treat polycystic ovary syndrome, hair loss and other problems caused by elevated testosterone levels. Below you will find instructions for using this medicine, written in clear language. Study its indications, contraindications and side effects. Find out how to take Veroshpiron: in what dosages, how many days in a row, before or after meals. Read about Inspra tablets, which have a similar effect, but do not cause impotence and growth in men mammary glands. Find out whether Veroshpiron is compatible with alcohol, whether this medicine helps with acne and for weight loss. The drugs Veroshpiron and Inspra can improve the results of treatment of heart failure and high blood pressure. Read more below.
| Pharmacological action | Spironolactone is the active ingredient of the drug Veroshpiron. It weakens the effect of the hormone aldosterone, which is produced in the adrenal cortex. Aldosterone is a hormone that stimulates the excretion of potassium in the urine, while causing water and sodium retention in the body. Spironolactone is an aldosterone antagonist, i.e. it has the opposite effect. Taking this medicine stimulates the excretion of water and salt and thus reduces swelling. At the same time, the potassium content in the blood increases. Veroshpiron has a weak and inconsistent diuretic effect. It appears on the 2-5th day of daily use. |
| Pharmacokinetics | Spironolactone is quickly and completely absorbed from the gastrointestinal tract. It is excreted primarily by the kidneys rather than the liver. Spironolactone and its metabolites penetrate poorly into organs and tissues, but overcome the placental barrier and enter the breast milk. In patients suffering from liver cirrhosis and heart failure, the active substance of the drug Veroshpiron lingers longer in the body, but does not accumulate. The concentration of spironolactone in the blood may increase if the patient has kidney failure. |
| Indications for use | Arterial hypertension- Veroshpiron is added to standard treatment, if otherwise it is not possible to lower your blood pressure to 140/90 or lower. Edema caused by chronic heart failure. Primary hyperaldosteronism is increased production of aldosterone due to disease of the adrenal glands. Ascites is the accumulation of fluid in the abdominal cavity. Edema in liver cirrhosis, if the patient has an increased level of aldosterone in the blood. Veroshpiron is also used to treat polycystic ovary syndrome, excess hair growth (hirsutism) and other manifestations of high testosterone in women. Men sometimes take it for hair loss. But these problems are not included in the list of official indications for use. |
| Contraindications | Hyperkalemia is an increased level of potassium in the blood. Hyponatremia - sodium deficiency. Severe renal failure - rate glomerular filtration kidneys below 10 ml/min. Anuria - cessation of urine flow into the bladder, lack of urge to urinate. Children under 3 years of age. Allergic reactions - increased sensitivity to spironolactone or excipients that are part of the drug. Veroshpiron is prescribed with caution to patients who have excess calcium in the body, metabolic acidosis, AV block, or complications of diabetes on the kidneys. Old age, liver failure, liver cirrhosis - factors increased risk side effects. |
| Special instructions | While you are taking Veroshpiron, regularly monitor the levels of potassium and other electrolytes in the blood, as well as creatinine and other indicators of kidney function. Take blood and urine tests regularly, at intervals prescribed by your doctor. Learn the symptoms in the Spironolactone article. higher level potassium in the blood, ways to prevent and treat this side effect. Veroshpiron and alcohol are not compatible. Do not drink alcohol at all while you are taking this medicine. Spironolactone may cause drowsiness, weakness, and fatigue. You should not drive or perform hazardous work, at least at the beginning of treatment with this medicine, until the body adapts. |
| Dosage | The doctor selects the dosage of the drug Veroshpiron strictly individually. Adults are prescribed 25-400 mg once a day or the daily dose is divided into 2-3 doses. Uncontrolled hypertension - 50-100 mg per day. The effect of adding Veroshpiron to other medications will appear no earlier than after 2 weeks. For edema caused by heart failure or cirrhosis of the liver, you can start with 100 mg per day, and then increase or decrease the dose based on the result. If you have to prescribe Veroshpiron to children, then start with 1-3.3 mg/kg body weight per day in 1-4 doses. After 5 days, the dosage can be increased if necessary. |
| Side effects | Possible drowsiness, dizziness, indigestion, diarrhea, nausea, vomiting, headache, allergic reactions. To reduce the risk of dizziness, rise slowly from lying or sitting positions. Read more about side effects in the article “Spironolactone”. Learn the symptoms of high blood potassium levels, prevention, and treatment. Veroshpiron may cause serious side effects. But for patients who have indications for its use, the benefits of the medicine are greater than the negative effects. Pay attention to the medicine Inspra (eplerenone). It has a similar effect without causing problems in men. Read more about this drug below in the section “ Frequently asked questions and the answers to them." |
| Pregnancy and breastfeeding | Animal studies have shown a negative effect of spironolactone on pregnancy. No trials have been conducted in pregnant women. During pregnancy, Veroshpiron can be prescribed only in those rare cases when the expected benefit for the mother is significantly higher than possible risk for the fetus/child. One of the metabolites of spironolactone passes into breast milk. Therefore, if you need to be treated with this drug, breastfeeding should be stopped. Pregnancy is one of the official contraindications to the use of spironolactone. |
| Interaction with other drugs | Veroshpiron enhances the effect of diuretics and other blood pressure pills. It is for this purpose that he is appointed. Reduces the toxicity of cardiac glycosides. Increases the risk of intoxication with digoxin and lithium preparations. Veroshpiron can interact negatively with many medications. Tell your doctor about all medications, dietary supplements, and herbs you take and discuss interactions with them. Avoid salt substitutes that contain potassium. Do not drink alcohol while you are taking spironolactone. It is advisable not to take aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs). |
| Overdose | Symptoms of overdose - nausea, vomiting, dizziness, decreased blood pressure, diarrhea, skin rash. Increased levels of potassium in the blood cause muscle weakness, disorders heart rate. Due to sodium deficiency, dry mouth, thirst, and drowsiness may occur. There is no specific cure for an overdose of the drug Veroshpiron. Symptomatic therapy is carried out - induce vomiting, perform gastric lavage. To normalize the level of potassium in the blood, droppers with glucose and insulin are placed. In severe cases, patients are saved by dialysis. |
| Release form | Spironolactone 25 mg tablets - white, round, flat, marked “VEROSPIRON” on one side, with a characteristic odor. Capsules of 50 and 100 mg of spironolactone are hard, consisting of a body and a cap. Their contents are a fine-grained granular powder mixture of white color. |
| Storage conditions and periods | The packaging of the medicine Veroshpiron should be stored out of the reach of children at a temperature not exceeding 30°C. Shelf life - 5 years. |
| Compound | The active ingredient is spironolactone. Excipients- colloidal silicon dioxide, magnesium stearate, talc, corn starch, lactose monohydrate. The composition of the hard capsule is titanium dioxide, dyes, gelatin. |
Veroshpiron needs to be taken for a long time, for life, like other medications for hypertension and heart failure. It is not recommended to take any breaks without consulting your doctor. Unauthorized withdrawal or reduction of dosage can cause deterioration of the condition, even death. Mild side effects are not a reason to independently adjust your medication regimen. And if you are concerned about serious side effects, discuss them with your doctor quickly. Veroshpiron can be taken before or after meals, whichever is more convenient for you. Taking this medication with food may reduce the risk of nausea and diarrhea compared to taking it on an empty stomach.
It may be worth taking Veroshpiron before 6 pm so that you have to get up to go to the toilet less often at night. However, in many patients the diuretic effect of this medication is weak or absent altogether. This is normal, don't worry. Blood pressure may not begin to decrease immediately, but after 2-3 weeks. It is not recommended to drink any alcoholic beverages while you are taking spironolactone. This medicine increases the risk of getting into an accident while driving a car or driving dangerous machinery. It is recommended to take blood tests for potassium and creatinine levels 2-3 days after starting to take Veroshpiron, then again after 4-5 days. Then they are rented out for 3 months every month, then once every 3 months. If the doctor changes the dosage of Veroshpiron, the level of potassium and creatinine in the blood should be checked after a week.
Below are answers to questions that patients often have.
Veroshpiron or Inspra: which is better?
Inspra (eplerenone) is a medication that was introduced relatively recently, in the early 2000s. It is similar in action to Veroshpiron (spironolactone), but does not cause impotence and enlarged mammary glands (gynecomastia) in men. This drug is also less likely to cause hyperkalemia - increased levels of potassium in the blood. Men who are afraid of the side effects of Veroshpiron tablets should pay attention to the drug Inspra. But do not change one pill for another without consulting your doctor.
The drug Inspra has fewer indications for use than Veroshpiron. It is prescribed for heart failure of functional class II-IV, as well as after a heart attack. Arterial hypertension in the absence of heart failure is not an indication for the use of Inspra, nor is cirrhosis of the liver. Inspra tablets are expensive. They don't yet have cheap analogues. Due to their high cost, they are not popular in Russian-speaking countries, despite their significant advantages. Discuss with your doctor whether you should switch from Veroshpiron to Inspra. Don't do this yourself.
Veroshpiron or Indapamide: which is better?
Veroshpiron and Indapamide are different drugs. They have similar indications for use, but they are prescribed in different situations. It cannot be said that Indapamide is better than Veroshpiron, or vice versa. Indapamide is one of the first choice drugs for hypertension. A competent doctor will not prescribe Veroshpiron for high blood pressure in the first place. This remedy is sometimes added to more popular blood pressure pills if they don't help enough. You may be prescribed to take Indapamide and other medications at the same time for hypertension, and later Veroshpiron will be added to them. Indapamide is formally a diuretic drug, but in practice it is used as a vasodilator. Veroshpiron does not have a vasodilator effect.
Heart failure is an indication for the use of Indapamide tablets, but they are rarely prescribed because they are considered weak. If a patient with heart failure only needs to take Indapamide to compensate and does not need stronger diuretics, then he is unlikely to be prescribed Veroshpiron. As a rule, for heart failure, it is not Indapamide that is used, but a stronger loop diuretic, for example, Diuver (torasemide). And if necessary, Veroshpiron is added to it. Do not take any of the medications listed above on your own. To treat hypertension and heart failure, find an experienced doctor and follow his recommendations.
Diuver or Veroshpiron: which is better? How to take these medications at the same time?
It cannot be said that Diuver is better than Veroshpiron, or vice versa, because these are different medicines. They are prescribed for different purposes. Both drugs are diuretics, but they belong to different groups. Diuver is a loop diuretic, and Veroshpiron is a potassium-sparing diuretic. Diuver is one of the popular medications for heart failure. It actively acts on the kidneys, stimulating them to excrete more fluid and salt. Thanks to this, swelling in patients decreases and their well-being improves. Veroshpiron is sometimes prescribed for severe heart failure in addition to Diuver tablets and other basic medications.
For hypertension not complicated by heart failure, Diuver and other loop diuretics are usually not used. Because these medications cause significant side effects. Doctors usually prescribe drugs that act more mildly for high blood pressure. It happens that even the simultaneous use of several medications does not allow blood pressure to drop to 140/90 mmHg. Art. Many patients with severe hypertension benefit from adding Veroshpiron to standard treatment. It is not recommended to use Diuver in such situations.
Patients often have to take Diuver and Veroshpiron simultaneously for heart failure, along with other medications. Take all prescribed medications in the dosages prescribed by your doctor or as provided in the instructions for use. Do not attempt to arbitrarily reduce dosages or discontinue any medications. This may worsen the patient's condition or even lead to fatal outcome. If you suspect that any pills are causing side effects, discuss this with your doctor. In addition to taking your medications, follow the heart failure treatment guidelines found in the links below on this page.
Veroshpiron or Hypothiazide: which is better?
It cannot be said that Veroshpiron is better than Hypothiazide, or vice versa, because these are different drugs, they have different indications for use. Hypothiazide is a thiazide diuretic, and Veroshpiron is a potassium-sparing diuretic. Hypothiazide is one of the main medications for high blood pressure. It can be prescribed as soon as hypertension is diagnosed. As a rule, Hypothiazide is prescribed together with some other medications. Perhaps the patient will be discharged combination tablets, which contain hydrochlorothiazide (dichlorothiazide) - the active ingredient of the drug Hypothiazide. If a medication regimen that includes Hypothiazide does not reduce blood pressure to at least 140/90 mm Hg. Art., then they can add Veroshpiron. Patients with hypertension sometimes have to take Hypothiazide, Veroshpiron and other medications at the same time. Nobody likes to take a lot of pills. But this is better than suffering a heart attack or stroke.
Hypothiazide may also be prescribed for edema in heart failure. But more often they use Diuver (torasemide) or another loop diuretic. Because these are more potent medications than thiazide diuretics. Veroshpiron is prescribed for severe heart failure in addition to basic medications. It rarely happens that a patient is prescribed both Hypothiazide and Veroshpiron. If the patient is helped enough by Hypothiazide to compensate for heart failure, then there is usually no need to add more Veroshpiron. Do not take any of the medications listed above on your own. Both Hypothiazide and Veroshpiron can cause significant side effects. They are not suitable for self-medication.
How to take Veroshpiron and Asparkam at the same time?
You should not take Veroshpiron and Asparkam or other potassium preparations at the same time. Veroshpiron can cause hyperkalemia - an increase in potassium levels in the blood. This is not useful, but dangerous, and can cause deterioration in health and even death due to cardiac arrest. Taking Asparkam tablets increases the risk. Symptoms of hyperkalemia are weakness, fatigue, nausea, vomiting, tingling sensation, goosebumps, difficulty breathing, chest pain, obvious heart rhythm disturbances.
While you are taking Veroshpiron, do not use Asparkam, other potassium preparations, or salt substitutes rich in this mineral. Veroshpiron interacts negatively with many medications. To reduce your risk, tell your doctor in advance about all the medications, herbs, and dietary supplements you take.
Why is Veroshpiron prescribed to children?
Veroshpiron is prescribed to children for the treatment of heart failure, fluid accumulation in the abdominal cavity (ascites), and primary hyperaldosteronism. This drug helps reduce pulmonary congestion in newborns with lung diseases. Failing to take diuretics or amphotericin can lower your child's potassium levels. In such cases, in addition to other measures, Veroshpiron is prescribed. The doctor selects the dosage of the drug taking into account the age and body weight of the child. Veroshpiron should never be given to children for self-medication. All the diseases listed above are serious. They are treated in a hospital setting.
Can I drink alcohol while taking this medicine?
Is it possible to drink Veroshpiron during pregnancy?
Pregnancy and breastfeeding are official contraindications to the use of the drug Veroshpiron. Animal studies have shown that this medicine has negative effects on the fetus. Taking Veroshpiron for edema during pregnancy is a bad idea. Study the article “High blood pressure in pregnant women.” Find out what medications you can take, how to get by with the minimum amount of them, what to do to prevent preeclampsia and eclampsia. Talk to your doctor about how to reduce swelling or get rid of it completely without using dangerous medications.
Can I take this drug when planning a pregnancy?
No more shortness of breath, headaches, pressure surges and other symptoms of HYPERTENSION! Our readers are already using this method to treat blood pressure. Find out more...
There is no data on how dangerous or safe it is to take Veroshpiron when planning pregnancy. If you are so serious illness If you need to take this medicine, then postpone planning your pregnancy.
Veroshpiron (spironolactone) is a medicine that is often prescribed to seriously ill patients with hypertension and heart failure. It helps reduce swelling caused by heart problems or cirrhosis of the liver. Sometimes women take Veroshpiron to treat polycystic ovary syndrome and other manifestations of high testosterone. Spironolactone tablets may help with acne and hair loss in women. But this is not confirmed by the results clinical trials. Official indications for use are only severe hypertension, heart failure, liver cirrhosis and also a disease of the adrenal glands, which is called primary hyperaldosteronism. Veroshpiron definitely does not help men with acne or hair loss.
It is known that Veroshpiron in dosages of 100 mg per day causes impotence and breast enlargement (gynecomastia) in some men. Many men would benefit from taking Veroshpiron for hypertension and heart failure. But they refuse to take this medicine, fearing the side effects listed above. Such patients should pay attention to the drug Inspra. It has an effect similar to the therapeutic effect of Veroshpiron tablets, but does not pose a threat to men. This medicine is described in detail above. Read the answer to the question “Veroshpiron or Inspra: which is better?” Do not change Veroshpiron to Inspra without permission. Discuss this possibility with your doctor.
Veroshpiron is not the first choice drug for high blood pressure. But it is often prescribed to people whose standard hypertension treatment does not help lower blood pressure below 135-140/90 mm Hg. Art. In many patients, severe hypertension is caused by elevated levels of the hormone aldosterone in the blood. In such cases, it is worth adding Veroshpiron to more popular medications for high blood pressure. It is advisable for patients to undergo blood and urine tests for aldosterone and other hormones produced by the adrenal glands. But Veroshpiron is often prescribed without testing, and this helps many patients.
Veroshpiron and other spironolactone drugs have been used to treat severe hypertension since the 1960s. Currently, interest in this medicine is not decreasing, but rather increasing. Malignant hypertension is when a patient's blood pressure is above 140/90 mm Hg. Art., despite the fact that he takes 3-4 antihypertensive medications belonging to different groups, one of which is a diuretic. About 10% of patients suffer from malignant hypertension. There is still no effective and safe remedy that would help most of them. However, Veroshpiron is beneficial in many cases of malignant hypertension.
In November 2015, the reputable medical journal Lancet published English results of the PATHWAY-2 study. We compared spironolactone (Veroshpiron), bisoprolol and doxazosin as an add-on drug for malignant hypertension refractory to standard treatment. The study involved more than 300 patients whose blood pressure was above 135-140/90 mmHg. Art., despite 3 months of taking ACE inhibitors, calcium antagonists and thiazide diuretics. Spironolactone has proven to be more effective effective medicine than bisoprolol and doxazosin. The newer drug Inspra, which does not cause dangerous side effects in men, has no evidence base for high blood pressure. Hypertension not complicated by heart failure is not an indication for its use.
A competent doctor will not prescribe Veroshpiron for high blood pressure to a patient who has recently been diagnosed with hypertension. Because side effects can be serious, and they happen often. First of all, more safe medicines, than Veroshpiron. In most cases, it is enough to take them to keep blood pressure normal. Moreover, if the patient tries to lead healthy image life. But for malignant hypertension, Veroshpiron should be prescribed because possible benefit- higher than the risk of side effects. Veroshpiron helps many patients with severe hypertension. The effect of adding this drug to standard treatment usually does not appear immediately, but after 2-3 weeks.
Veroshpiron (spironolactone) should be prescribed to patients with severe heart failure of functional class III–IV and ejection fraction
Watch also the video: Almost all patients with heart failure receive a powerful diuretic drug related to loop diuretics, - Diuver (torasemide) or similar drug. Veroshpiron is prescribed not to enhance the diuretic effect, but to block the action of the hormone aldosterone. As a rule, in heart failure there is an increased concentration of this hormone in the blood. Aldosterone removes potassium and magnesium from the body, retains salt, and also promotes the replacement of the heart muscle with scar tissue. Taking the drug Veroshpiron reduces the negative processes listed above. Due to this, the prognosis for patients improves.
40-50% of patients with heart failure are patients whose ejection fraction is not reduced, but normal. Unfortunately, doctors do not really know how to treat such patients. Medicines commonly prescribed for heart failure do not improve prognosis, rigorous studies have shown. A large trial was conducted to test the effectiveness of spironolactone (Veroshpiron) in patients with heart failure who have a normal ejection fraction. This study was called Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT). Several thousand patients from different countries peace. For some reason, spironolactone helped patients from the USA a little, but not at all for Russian patients. You can read an article in English about this. The reason is that the criteria for diagnosing “heart failure” are different in Russian-speaking and foreign countries.
Men who have developed heart failure after a myocardial infarction should pay attention to the drug Inspra. This is a newer drug that helps like Veroshpiron, but does not cause breast growth and probably does not affect male potency. More details about this medicine are described above. Study the answer to the question “Veroshpiron or Inspra: which is better?” Unfortunately, Inspra costs tens of times more than Veroshpiron. This is an original imported drug that does not yet have cheap analogues. You cannot change your medication regimen for heart failure on your own. If you want to switch from Veroshpiron tablets to Inspra, discuss this with your doctor.
Veroshpiron is not the main medicine that women take for polycystic ovary syndrome. Perhaps taking these pills helps control hirsutism - excess hair growth on the chin and torso. Women who do not have hirsutism probably do not need to take Veroshpiron if they have polycystic ovary syndrome. If your doctor has prescribed Veroshpiron for you, then take it at the indicated dosage, 25-200 mg per day. Your doctor may initially prescribe a low dose of spironolactone and later increase the dose. Blood tests for potassium show whether the patient is tolerating treatment with this drug.
According to patient reviews, Veroshpiron for polycystic ovary syndrome needs to be taken for a long time - 6-9 months - before a decrease in hirsutism becomes noticeable. Possible side effects include nausea, menstrual irregularities and increased breast size. If you stop taking the medicine, excess hair growth will begin again. To solve the problem of hirsutism, other drugs are used, not just Veroshpiron. But this topic goes beyond the scope of the site about the treatment of hypertension. A diagnosis of polycystic ovarian disease means that a woman has an increased risk of type 2 diabetes. It is useful for such patients to follow a low-carbohydrate diet, which is also used for prevention. cardiovascular diseases.
Veroshpiron is often used for swelling of the legs caused by pulmonary hypertension, or if the cause of fluid accumulation is not determined. Swollen legs can be a warning sign that life-threatening heart or kidney failure is just around the corner. Therefore, you should not try to treat them yourself by taking spironolactone or stronger diuretics.
Contact your doctor to find the cause of the swelling and, if possible, eliminate it. If venous insufficiency is detected, you will need to keep your legs elevated at night, wear compression stockings, and most importantly, quit a job that requires you to be on your feet for a long time. Horse chestnut extract is also popular. For deep vein thrombosis of the lower extremities, the doctor will prescribe low molecular weight heparin.
Before taking Veroshpiron, make sure that the cause of edema is not heart or kidney failure or liver disease. You need to undergo a thorough examination. If it does not help determine the cause of the edema, the doctor may diagnose “idiopathic edema” and prescribe Veroshpiron. Take this medication at the dosage directed by your doctor. At the same time, regularly take blood tests to check potassium levels and other indicators.
If Veroshpiron does not help enough, after a few weeks Hypothiazide, Indapamide or another thiazide diuretic may be added in a low dose. In this case, it is better to avoid diuretic drugs, which are classified as loop diuretics. In addition to taking medications, your doctor will recommend limiting your salt intake and avoiding overexposure to the sun. It is advisable for patients who are overweight to lose weight. Don't take swollen feet lightly. Get tested to determine the cause and try to eliminate it rather than dull the symptoms with diuretics.
Testosterone is the main male sex hormone. It is present in the body of women, not just men. But in women it is normally much less than female sex hormones. With some endocrine diseases, the level of testosterone in the body of women is increased. This causes menstrual irregularities, acne and excess hair growth where there shouldn't be any. It is possible that testosterone may cause some women to experience less hair on their heads after menopause. Polycystic ovary syndrome is not a consequence, but one of the causes of increased testosterone in women. Other reasons - congenital hyperplasia adrenal cortex, ovarian tumor.
If a woman is concerned about the symptoms of high testosterone, she needs to find a competent endocrinologist and contact him. The doctor will recommend leading a healthy lifestyle, prescribe medications and possibly prescribe surgical treatment. Veroshpiron is one of the medications that can be prescribed to reduce the effects of increased testosterone levels in a woman’s body. Perhaps this drug helps middle-aged women with scalp hair loss. But this has not been officially confirmed.
Veroshpiron often causes serious side effects - fatigue, dizziness, headaches and decreased libido. Therefore, do not take it for self-medication. Other popular medications are Siofor (metformin), glucocorticosteroids, and well-chosen birth control pills. Increased testosterone in women is serious problem which is impossible to solve on your own. Find a smart doctor and consult with him. Do not take the medications listed above on your own initiative.
A common complication of liver cirrhosis is ascites, an accumulation of fluid in the abdominal cavity. When a lot of fluid accumulates, patients experience symptoms - heaviness in the abdomen, shortness of breath, a decrease in the amount of food needed to satiate. To relieve the symptoms of ascites, diuretics are prescribed - most often Veroshpiron along with furosemide (Lasix). You can start with a dosage of 100 mg of Veroshpiron and 40 mg of furosemide per day. If this dosage does not help enough, after 3-5 days it is increased to 200 mg of spironolactone and 80 mg of furosemide.
Maximum possible daily dose diuretics for liver cirrhosis - Veroshpiron 400 mg and furosemide 160 mg. It is recommended to prescribe these drugs in a ratio of 100:40 to maintain a normal balance of electrolytes in the blood. In 5-10% of patients, fluid accumulation in the abdominal cavity does not decrease, even despite taking spironolactone and furosemide in maximum dosages. Or ascites is restored to its previous level immediately after discontinuation of diuretic drugs. The prognosis for such patients is poor.
It is advisable to prescribe Veroshpiron for hypertension to patients with type 1 and type 2 diabetes mellitus, in whom ACE inhibitors, angiotensin-II receptor blockers and other basic medications do not help reduce blood pressure to 135-140/90 mm Hg. Art. Preparations containing spironolactone are used as an additional drug, and not to replace the main blood pressure tablets. Several clinical trials have been conducted that have confirmed the feasibility of this treatment. Their results were published in reputable medical journals. See for example the article “Beneficial effects of adding spironolactone to recommended antihypertensive treatment in diabetic nephropathy: a randomized, double-masked, cross-over study” in the journal Diabetes Care, September 2005.
Read the article “High Blood Pressure in Diabetes”. Understand the difference between the treatment tactics for hypertension in type 2 and type 1 diabetes. Find out in detail which tablets are prescribed for the treatment of hypertension with diabetes mellitus. Read what a low-carb diet is, how it differs from a standard “balanced” diet, and what benefits it brings. A low-carbohydrate diet allows you to maintain stable normal blood sugar, like healthy people. It will give you the opportunity to minimize the amount of hypertension medications you need to take, or even stop taking them altogether.
Many women face the problem of hair loss on their scalp after menopause, or even earlier. The main medicine used in such cases is Minoxidil, a vasodilator drug for hypertension. Sometimes women also take Veroshpiron or other spironolactone drugs for hair loss. Spironolactone tablets are thought to help some women who have not benefited from the drug Minoxidil.
Veroshpiron is not officially approved for use against hair loss in women, much less in men. Possible side effects from taking it by women are weight gain, decreased libido, depression, and fatigue. Women of reproductive age who take Veroshpiron for hair loss are advised to use reliable methods of contraception. Because spironolactone can have negative effects on the fetus.
Abroad, Veroshpiron is often prescribed for acne to women who have already completed puberty. This is not the first choice acne treatment. Treatment with this drug should be considered in patients who do not respond to simple methods, without the use of hormonal drugs. Veroshpiron against acne only helps women, and not everyone. It is not prescribed to teenage girls. You need to take this medicine for at least 3 months before it becomes clear whether it helps you or not.
Dermatologists sometimes prescribe veroshpiron tablets to women for acne. Clinical trials have confirmed the effectiveness of this method. But the treatment acne it's still gone official testimony to the use of the drug Veroshpiron. The fact is that this drug stimulated the development of cancer in laboratory animals that received it in very high doses. Therefore, the US Department of Health (FDA) does not want to expand the list of indications for the use of spironolactone.
Do not take Veroshpiron for acne on your own initiative. Find a competent dermatologist and consult with him. An intelligent specialist, before prescribing Veroshpiron or other treatment, will force the patient to take blood tests for male sex hormones and aldosterone. A common side effect is a drop in blood pressure, associated weakness and dizziness. Menstrual irregularities are also possible. If acne bothers you, consider taking zinc and vitamin A tablets.
Taking Veroshpiron for weight loss is a bad idea. This medicine acts as a diuretic and may reduce appetite. However, its diuretic effect is weak, does not appear immediately, and in many patients is completely absent. There is not the slightest reliable evidence that spironolactone tablets help you lose excess weight. Your body weight may even increase due to the hormonal changes this drug causes. No specialist in his right mind would approve of taking Veroshpiron tablets for weight loss, or other diuretic drugs.
Many women try to take diuretics to quickly lose a few pounds. The most popular diuretic drug for weight loss is furosemide (Lasix). This medicine may cause serious side effects. However, they will go away quickly after stopping the medication if the kidneys have not been permanently damaged. The side effects that Veroshpiron will cause may remain with you for a long time even after stopping the drug. If you are interested in weight loss medications, then pay attention to Siofor (metformin). Of course, it is better to focus on healthy eating and physical activity.
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2018 Blog about women's health.
If a doctor has prescribed Veroshpiron tablets, instructions for use are usually located inside the drug package. If for some reason it was not there, then it will be useful to read the following information, which describes the indications and contraindications for the use of Veroshpiron, side effects and drug analogues.
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Veroshpiron is a 25 mg tablet with a diameter of 9 mm. Externally, these are white round preparations with markings. Sometimes the drug is available in 50 mg capsules. The capsules consist of a white powder-like mixture with a characteristic mercaptan odor. There are also 100 mg capsules, as well as gelatin versions of opaque yellow. The medicine is very quickly absorbed into the gastrointestinal tract and excreted naturally. As a rule, the diuretic effect of the drug appears on the second day of taking the medicine.
The drug is produced in blisters of 20 tablets, capsules of 50 and 100 mg are produced in blisters of 10 pieces. The medication is dispensed in pharmacies only with a doctor's prescription.
The main active ingredient in this drug is spironolactone, which is respectively contained in tablets of 25 mg, 50 mg and 100 mg. Additionally, the product contains the following excipients:
Thanks to all of the above components, the drug Veroshpiron has a good diuretic effect.
You can take the medicine, as the instructions say, in the following cases:
In addition to the indications for use, like any other drug, Veroshpiron has contraindications, including hypersensitivity of the body and personal intolerance to one of the components that make up the drug. You should not take it if you have severe kidney problems or kidney failure.
The drug should be used with caution in people with hepatitis and severe liver diseases, if acid-base balance in the body and the presence of diabetes.
It is strictly forbidden to use the medicine during pregnancy, lactation and children under 6 years of age. Taking into account the fact that the drug helps increase the amount of potassium in the patient’s body, the dosage must be strictly observed during treatment. Otherwise, an uncontrolled increase in potassium in the blood will negatively affect the functioning of the cardiovascular system and cause a number of side effects.
If the dosage of the drug is not correct, patients may experience an increase in heart rate, decreased sex drive, enlarged breasts in men, problems with erectile function, and an inability to conceive a child. Women experience nausea, vomiting, dizziness and menstrual irregularities. Common symptom confusion, decreased blood pressure, lethargy, decreased performance and hemoglobin levels, exacerbation of chronic diseases. In rare cases, it may develop:
The chance of developing the above side effects is only 1%, and most of them go away as soon as the patient stops taking the medicine. If you have any health changes that are not listed above, tell your doctor. He's in mandatory change the diuretic or reduce the dosage of the drug. In case of overdose of the drug, immediate gastric lavage is required.
If you have used or are using other medications, you also need to warn your doctor about this, because when Veroshpiron is prescribed and its dosage is developed, the doctor must take into account all the characteristics of the patient’s body. The patient may experience a negative reaction if he takes the following drugs simultaneously with Veroshpiron:
It is important to note that the drug may affect concentration, so it is not recommended to drive while using the drug.
Each Veroshpiron tablet contains a certain amount of milk sugar. If a person has lactose intolerance, it is possible allergic reaction for the drug.
The daily dose of the drug should be indicated by the doctor depending on the severity of the disease. As a rule, the first dose of the medicine should be taken in the morning before meals. You can take the drug with a small amount of water or juice, but in no case with coffee.
In the treatment of high blood pressure, the drug is taken 2 times a day along with other antihypertensive drugs. Veroshpiron is a diuretic and is used as an additional therapy. In the treatment of edema caused by kidney and liver diseases, the doctor prescribes large doses of the drug. This diuretic drug is often used in gynecology and urology, when preparing a person for surgery. When treating children, the dosage is selected depending on the weight and age of the patient.
If it happens that you forget to take the medicine at the right time, under no circumstances take a double dose at once, just try to follow the administration method in the future. Do not use the drug after the expiration date indicated on the package and do not take tablets from damaged packaging.
The international nonproprietary name of the drug is Spironolactone, although it is sold in pharmacies under the name Veroshpiron. INN is used, as a rule, in medical practice, while pharmacologists sell the drug and its analogues under proprietary names. Among the analogues of the drug, the following drugs can be noted:
Each of the above medications can be purchased at a pharmacy at an affordable cost, but only with a doctor’s prescription. Before using the drug, in any case, read the instructions and follow the storage conditions for the drug indicated on the package.
This publication is for informational purposes only and is not a call for self-medication or the purchase of the above drugs. Only a doctor should prescribe the dosage!
The main action of spironolactone, known as trade names“Veroshpiron”, “Aldactone”, “Vero-Spironolactone”, “Veroshpilaktone” - diuretic and antihypertensive. The drug is effective for edema and high blood pressure associated with hypersecretion of aldosterone (adrenal cortex hormone), since it competes with it for binding sites on mineralocorticoid receptors.
The effect in the treatment of hirsutism was found, surprisingly, in men: many of them developed reversible gynecomastia. Laboratory research showed that spironolactone affects the concentration of androgens in the blood in several ways:
As a result of estrogen and progesterone activity, almost half of women experience disruptions in the menstrual cycle. Hence, two modes of taking the drug arose:
The hormonal effects of spironolactone were discovered in the mid-70s - then Veroshpiron began to be prescribed as additional remedy in the treatment of hirsutism in women at a dose of 50-200 mg per day. It was usual treatment PCOS in the 80s, but already in the early 90s they began to gradually abandon it in favor of finasteride and cyproterone. Now spironolactone is prescribed together with oral contraceptives when they or other medications are powerless.
The drug has a long list of side effects, but not fatal and reversible effects. This is perhaps not so bad, considering the side effects or. For fertile women, contraception is necessary, since taking Veroshpiron during pregnancy can lead to abnormalities in the development of the fetal reproductive system.
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