The main factor in the loss of B6 is nervous tension and stress. Constant replenishment of the vitamin is required for people whose life activities are associated with sports and physical activity.
B6 deficiency in women during pregnancy and lactation is 100% (for comparison: ascorbic acid deficiency in a pregnant woman is 64%). Lack of vitamin B6 is less common in children; it increases with age, and is highest in men and women over 50.
Indications for use
Contraindications:
Symptoms of vitamin B6 deficiency: fatigue, drowsiness, depression, muscle weakness, circulatory problems, hair loss.
Chronic vitamin deficiency in the body is the cause of nervous disorders, cardiovascular diseases, dermatitis, arthritis, liver and biliary tract diseases. In total, B6 deficiency is responsible for the development of more than 100 diseases.
Vitamin B6 is found in foods:
Of all the foods that contain vitamin B6, the richest are proteins and grains. High content medicinal herbs include plantain, catnip, alfalfa and oat stalks.
Pharmaceuticals:
An overdose of B6 is rare, because it does not accumulate and is excreted in the urine. In case of excessive use of the drug possible short-term nervous breakdown and numbness of the limbs(as with any vitamin intoxication). No diseases caused by excess B6 have been identified.
Side effects: allergic reactions, itching, skin rashes. Increased acidity.
The daily norm is divided in half, morning and evening. The course is from one to three months. It is highly advisable to consult your doctor, as well as carefully study the instructions for use.
Daily value (approximately) in mcg:
How to inject vitamin B6? intramuscularly, in gluteal muscle or top part hips. Fill the syringe, turn it over, push the air bubbles up, release the air.
Pull the skin slightly, wipe with a swab dipped in alcohol. Inject slowly, and when finished, wipe the injection site with an alcohol swab.
Vitamin B6 injections are painful and should not be used without medical advice.
Vitamin Magne B6 in ampoules, application: for adults and children over one year old (from 10 kilograms), the recommended dose is no more than 4 ampoules per day. Divided into two or three doses. The contents of the ampoule should be mixed with ½ glass of water. Take with food.
A mask that works great is made from a beaten egg, three oils (sea buckthorn, almond, burdock) one spoon each and the contents of three ampoules: B6, B2, B12. Keep the mixture on your hair under a film for an hour, rinse with shampoo.
Second option: the same thing with the addition of honey, castor oil, lemon juice, vitamins A, E, D. Keep for forty minutes.
The vitamin is eliminated from the body within eight hours. Regular replenishment is required. B6 contained in food is usually not enough for optimal vitamin balance.
But before prescribing treatment for yourself, you should consult with a therapist, even if you definitely have no contraindications to use. The doctor will suggest the most suitable regimen for taking B6 and tell you which drugs it should not be used together with.
Find all the details about B vitamins, their properties and daily dosage in.
The injection drug is sold in the form of 1 ml ampoules containing a 1% or 5% solution. The ampoule is a glass flask packed in a cardboard box. One box contains from 2 to 10 ampoules.
The drug can be stored in its original packaging for up to 3 years in a place protected from light. The solution should not be frozen or heated.
The average price in Russian pharmacies is 50 rubles.
1 ml of the drug contains 50 mg of pyridoxine hydrochloride and 1 ml of water.
Vitamin B6 is a broad-spectrum medicine that eliminates many disorders in the body. It is involved in metabolic processes and in regulating the metabolism of the nervous system. The medicine is also used as a substance that promotes rapid recovery patient after surgery.
The injection solution promotes:
B6 is an important element necessary for the stable functioning of cells, metabolic processes, nervous and circulatory systems. The vitamin is delivered to human body with the food in which it is contained, and its deficiency can occur when poor nutrition, increased physical and mental stress, during pregnancy or frequent stressful situations.
Injections with this drug are prescribed in the following cases:
At complex therapy injections can be prescribed for:
The drug is absorbed into the small intestine, and then accumulates and is distributed in the liver, central nervous system and some muscles. The solution penetrates well into all tissues of the body. It is excreted mainly in the urine.
B6 is gentle on the body, but still has a number of contraindications. The drug is not used for acute liver damage, hypersensitivity to components and coronary heart disease.
Injections are prescribed with caution for peptic ulcers and problems with 12 duodenum. This is due to a possible increase in acidity in the stomachs.
With caution and only as prescribed by a doctor, the solution can be injected during pregnancy and lactation, but only in the most serious cases, when the benefits to the health of the mother will be significantly higher than the risks to the fetus. Such cases include, for example, severe toxicosis.
Pyridoxine is introduced into the body by several methods:
Thus, the solution begins to act most quickly when intravenous administration. This method is used for acute cases diseases. For chronic ailments and prevention, injections are given intramuscularly, and if the drug is used independently at home, then injections are allowed subcutaneously.
Vitamin B6 is introduced into the human body using an injection, which can be given by either a medical professional or a lay person. To do this, you must follow some rules:
The daily dose of injections for administration differs depending on the patient's disease. Most often, pyridoxine in liquid form is prescribed as follows:
Treatment therapy traditionally lasts for a month for adults and 14 days for children.
In the case of other diseases, the amount of the drug required for use per day is prescribed individually by the attending physician, depending on the severity of the disease and other factors.
The drug has special instructions for the treatment of anemia. Even with acute syndrome disease, it is worth administering 100 mg of solution no more than twice every 7 days.
To prevent hypovitaminosis in adults, the drug is prescribed at 4-5 mg per day, and for children, 2 mg per day is prescribed. Well preventive treatment usually does not exceed 2 months.
Pyridoxine is low-toxic and extremely rarely causes poisoning and other types of overdose. In some cases, after an injection, an allergic reaction, a feeling of tightness in the limbs, dizziness, and nausea may occur.
If the patient detects one of the signs, then use of the drug should be stopped. Usually, after a two-day break, the manifestations disappear. If the illnesses do not stop, the patient must inform the doctor about them.
Vitamin B6, like many other vitamins, is found in moderate quantities in certain plants and animals. For example, in cereals, some vegetables, meat products, fish and their liver, cow's milk, chicken eggs. A person receives the substance from these foods and does not have problems with deficiency, provided that daily dose vitamin It amounts to:
Vitamin B6 is incompatible with drugs such as thiamine and cyanocobalamin (vitamins B 1 and 12), ascorbic and nicotinic acid, available in powder form.
Russia, Moscow, Orlovsky lane, 7
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exacerbation with which NSAID to treat. I need a neurosurgeon
advised Ksefokam IM 2 times a day, 8 mg, in view of this
that it has fewer side effects than Movalis and
diclofenca. What do you recommend?
Is it possible to replace milgamma 2 ml. IM for vitamin B12, if
Yes, what dosage should be for injection.
2. Vitamin B12 is not an exact replacement for milgamma. If you need
cheaper, you can buy domestic analogue milgams -
"Daily" includes:
vitamin DME
vitamin B2 - 1.8 mg
vitamin B6 - 1.8 mg
vitamin B12 - 2 mcg
pantothenic acid - 9 mg
Can you suggest a replacement and give advice on treatment? (Thank you in advance. Marina
Discuss with your doctor the possibility of replacing this drug with cyanocobalamin (vitamin B12).
By the way, we did not find Vitasprint in the State Register medicines Russia.
The information provided is intended for medical and pharmaceutical professionals, should not be used for treatment and cannot be considered as official. The most accurate information about the drug is contained in the instructions supplied with the packaging by the manufacturer. No information posted on this or any other page of our website can serve as a substitute for personal contact with a specialist.
Please pay attention to the specified dates for entering information; information may become out of date.
Is it possible to combine these vitamins? Calculation of dosage, instructions for use of drugs in ampoules. Possible side effects.
B vitamins are elements that should be part of the diet and supplied in sufficient quantities for the body. This is especially important against the backdrop of a deteriorating environmental situation, addiction to bad habits and mass love for unhealthy food. There are several ways to fill the deficit:
Nutritionists and doctors agree that the latter option is more preferable. The only question is what are the features of the drugs in the ampoules, how to properly inject B vitamins, and what effect these substances have on the body.
The importance of the vitamins in question for the human body is difficult to overestimate. At the same time, the trinity deserves special attention useful elements from group B - B1, B6 and B12 (thiamine, pyridoxine and cyanocobalamin, respectively). They perform well in treating the central nervous system and normalizing metabolic processes. Moreover, each of them is responsible for separate processes:
Separately, it is worth noting the importance of B6 for children who are bottle-fed.
Cyanocobalamin is especially important during pregnancy, because it is responsible for the nervous system of the fetus, and its deficiency causes the development of serious pathologies at the intrauterine level. The daily requirement is:
Elements B1, B6 and B12 provide the following results:
At the same time, getting B vitamins from food in full is a difficult task. This will require additional use of special supplements. The question is which option to give preference to - tablets or injections. A popular form is tablets, but in this case the vitamins travel a long way to their destination: the esophagus, stomach and intestines. In this case, the body receives a small proportion of the substance. That is why the course of taking capsules is 1-2 months.
If you decide to use vitamins B1, B6, B12 in ampoules, instructions for use should be at hand. It is highly advisable to obtain a doctor's advice in advance. It is recommended to inject the mentioned drugs into the gluteal muscle. The best option is to use the help of a health professional or person with the required skills. If there is no such thing nearby, then the injection can be done independently, but not in the buttock, but in the upper lobe of the thigh.
Before performing any manipulations, you need to prepare:
The sequence of actions is as follows:
When the first drop appears, you can begin the procedure:
During the course, it is worth considering one more nuance - the compatibility of vitamins with each other:
Despite the compatibility of some drugs, it is not recommended to put them into one syringe. The ideal option is to alternate injections. One day - one drug, and the next - the next. So, B6 and B12 get along well with each other, but they should only be injected separately and preferably every other day.
When taking medications B1, B6 or B12 in ampoules, it is worth considering the following:
Practice has shown that drugs are easily tolerated, but in some cases they may adverse reactions, which are also observed in case of overdose:
Much has already been said about the benefits of B vitamins. Its representatives are of paramount importance. For example, in order for a woman to have a dazzling appearance, she must regularly replenish her body with them. They are available and can be purchased at any pharmacy. Vitamins are packaged in ampoules and can be either water or oil based.
Cyanocobalamin (vitamin B12) was discovered in 1948. It was isolated from raw liver. For a long time Scientists could not understand why patients who took raw liver in small quantities managed to overcome pernicious anemia.
Since then, vitamin B12 and its effect on the body have been studied quite well; all that remains is to understand that this is an expensive gift from nature that should be used wisely. Vitamin B12 helps avoid the effects of stress; it, with the help of vitamins B5, B9 and C, helps block stress hormones and helps restore nerve cells and participates in the construction of new ones, that is, it is an active participant in the processes of biosynthesis of amino acids and the synthesis of DNA and RNA. The substance improves the process of blood clotting and reduces the amount of cholesterol in it.
Vitamin B12 can be obtained from food or supplemented with tablets and injections. Cyanocobalamin is found in animal products, which is why vegetarians tend to suffer from a lack of it in the body. It is not synthesized in plants.
It is much more convenient to use vitamin B12 in ampoules. It is slightly liquid pink color. Indications for cyanocobalamin injections may include trigeminal neuralgia, hepatitis, neurodermatitis, anemia, Down syndrome, as well as migraine, diabetic neuritis, radiation sickness, multiple sclerosis, cerebral palsy. This vitamin affects reproductive function - both female and male. Has a beneficial effect on the human immune system. If the body of HIV-infected people does not have enough vitamin B12, the disease progresses much faster.
B12 injections should not be prescribed in the presence of erythrocytosis or hypersensitivity to the drug; caution must also be exercised in case of malignant and benign tumors and angina pectoris.
As mentioned above, vitamin B 12 belongs to the group of vitamins. It is widely used traditional medicine, as one of the components used for treatment various diseases or for their prevention. Therefore, if cyanocobalamin is prescribed by a doctor, then this is not subject to discussion, but if someone independently decided to inject vitamin B12 in ampoules, the instructions for use in this case are subject to detailed study.
First of all, you need to know that cyanocobalamin can be used intravenously, subcutaneously, or intramuscularly. And the instructions also detail that it cannot be used together with drugs that increase blood clotting; you also cannot mix vitamins B1, B6 and B12 in one syringe; in addition, if the patient has an allergic reaction to vitamin B1, then B12 can significantly strengthen. You cannot combine cyanocobolamin with riboflavin and ascorbic acid, but colchicine, antiepileptic drugs and salicylates can reduce the degree of its absorption by the body. And there are many nuances that only a doctor can know, so only he can fully answer the question of how to inject vitamin B12.
Vitamin B12 in ampoules, the price of which is quite reasonable - from 17 to 25 rubles, depending on the manufacturer, has a significant effect in the treatment of various diseases. As practice shows, many people inject cyanocobalamin when the following signs of deficiency of this vitamin appear:
Headache and dizziness;
Fatigue and weakness;
Irritability, neuritis and nervousness;
The appearance of ulcers on the tongue and in the mouth;
Pallor skin;
Decreased appetite, back pain and sleep disturbances.
This drug is prescribed by doctors for certain diseases and for their prevention. For what diseases is B12 prescribed, how to inject it correctly?
The course of prophylaxis can range from 7 to 15 days, with injections from 200 mcg to 500 mcg per day.
Diseases associated with the central and peripheral nervous system:
The first 3 days, 200 mcg daily;
The next 4 days, 300 mcg daily.
If no complications arise within seven days, the course of treatment ends. If complications occur, the dose is increased:
5 days daily 400 mcg;
The next 3 days, 500 mcg daily.
Another quite serious disease that occurs due to a lack of B12 in the body is anemia. A characteristic feature of this ailment is that it develops almost asymptomatically and slowly, but, as a rule, affects the nervous system. During treatment, cyanocobalamin is prescribed along with other drugs in a dose of 200 to 300 mcg; if complications arise, it is increased to 500 mcg and administered 1 or 2 times a day. If the patient's condition worsens, the dose can reach up to 1000 mcg. After 10 days it can be reduced, but for another 3 months the daily norm will be 300 mcg of the vitamin. And after the end of treatment, one injection is given every two weeks for six months.
Before injecting vitamin B12 in ampoules, it would be useful to familiarize yourself with the consequences in case of an overdose: if the body is hypersensitive to this substance, then a large dose can cause an allergic reaction, which will manifest itself in the form of urticaria (rash on the body and mucous membranes), as well as pain in the heart area, tachycardia, increased nervousness.
It should be remembered that an excess of cyanocobalamin is very difficult to remove from the body.
Cyanocobalamin is an excellent assistant in hair care. At home, the vitamin can be added to shampoo, thereby making it fortified. It is also added to hair masks. For example, an excellent mask against hair loss is to mix one teaspoon of honey and lemon juice and add one ampoule of vitamin B6 and B12 to the mixture. Apply the mixture to clean hair, leave for 10 minutes, then rinse. Repeat the procedure five times a week.
But, as you know, external application is always inferior in results to internal application. What to do if vitamin B12 cannot be used in the form of injections due to the individual characteristics of the body, but at the same time you want to have beautiful hair? In such cases, it is best to include foods containing cyanocobalamin in sufficient quantities in your diet.
Most vitamin B12 is found in beef or veal liver, but it is in large quantities also contain chicken and pork liver. It is also found in marine products such as crabs and oysters, fish, egg yolks, meat, hard cheese, dairy and fermented milk products.
Nowadays, fortified mixtures are offered in large quantities, for example, oatmeal, muesli in the form of breakfast cereals. In fact, it is unlikely that it will be possible to find the specified amount of vitamins there, because long-term storage helps to reduce it, and the preservatives contained in such products are harmful.
There is another caveat: vitamin B 12 is heat stable, which means it is not destroyed by cooking. But at the same time, direct sunlight has a detrimental effect on it.
As many reviews indicate, vitamin B 12 in ampoules with correct intake allows you to solve many problems. With its help, they have even achieved weight loss, and in general, it perfectly fights the deposition of fat in the liver. Perhaps this vitamin belongs to the category of those about which nothing bad can be said, except in cases where the consumers themselves overdosed, or when they started taking the drug without consulting a doctor, and the body reacted with an allergic reaction. To avoid unpleasant moments and taking the vitamin was beneficial, it is still better to consult a doctor. Perhaps he will even prescribe some specific tests, and then, based on their results, establish a norm and regimen for you.
Most of the population of our country have personally encountered such unpleasant problems as joint pathology, radiculitis, neuritis, neuropathies and anemia. Climate features, eating behavior, lifestyle and availability chronic diseases inevitably lead to the occurrence of any of these pathologies.
It is these diseases that often lead to weakness, increased fatigue, decreased performance and memory, the appearance of pallor of the skin and even pronounced pain syndrome. However, there is a safe solution to this issue.
A course of conventional vitamin therapy can lead to the disappearance of the diseases themselves and their symptoms, namely intramuscular injections vitamin B12.
According to the instructions for use, the pharmacological name of vitamin B12 is cyanocobalamin. This substance has high biological activity, which allows it to participate in all types of metabolism. Cyanocobalamin has many more positive effects on the body:
Despite the many points of influence, the main pharmacological actions of vitamin B12 are: antianemic, stimulation of erythropoiesis (the process of formation of new red blood cells), hematopoiesis - the synthesis of other blood cells, as well as the ability to restore nerve cells and elements of cartilage tissue.
Vitamin B12 is absorbed in the intestines. However, this process takes quite a long time (several hours) and most of the vitamin is excreted from the body without entering the systemic bloodstream. It is thanks to this property that cyanocobalamin is produced in ampoules containing a solution for intramuscular injection.
In the instructions for use for this drug all diseases and conditions for which doctors recommend taking a course of therapy with this drug are prescribed. These conditions include:
In many cases, cyanocobalamin is not suitable for monotherapy, but is only one of the components drug treatment. Despite this, clinicians often resort to the use of this substance to achieve faster and better results.
The solution of cyanocobalamin in ampoules is by its nature a vitamin, the composition of which does not differ from the vitamin that enters the body with food. Naturalness and safety of this medicinal substance cause a rather meager list of contraindications. Namely:
Also, the drug in ampoules is contraindicated in pregnant women, since there is clinical evidence of its harmful effects on the fetus.
If the patient normal level hemoglobin and red blood cells, then it is not advisable for him to prescribe a course of vitamin therapy with cyanocobalamin. And self-prescribing any drugs can lead to disastrous consequences.
It is non-compliance with contraindications, dosages and injection techniques that lead to such phenomena. To avoid them, follow your doctor's instructions.
Injections of cyanocobalamin can be carried out under the skin, into a muscle, into a vein, and also intralumbarally, that is, inside the spinal canal. However, most often the course of injections is administered intramuscularly.
The dosage of the drug ranges from 15 to 500 or even 1000 mcg per day. It depends on the condition of the patient and his disease. The duration of the course also varies and is selected by the doctor individually. On average, a course of vitamin therapy is 10–15 days.
As a rule, 1 injection per day is prescribed. One ampoule contains 1 ml of the drug, which contains 500 or 200 mcg of vitamin.
It must be remembered that vitamins B12, B6 and B1 cannot be mixed in one syringe, since pharmacologically they are not compatible in their composition.
From all of the above it follows that the drug is safe and very beneficial for the body. It is more advisable to use a B12 solution in ampoules, but if only oral administration is possible, then it is carried out in combination with Folic acid to improve the absorption process in the intestine.
During therapy with cyanocobalamin, you should monitor the dynamics in the peripheral blood picture. When the target levels of red blood cells and hemoglobin are achieved, the drug is discontinued.
The use of vitamin B12 as part of complex therapy for diseases of the joints, nervous or connective tissue not only leads to increased pharmacological action basic drugs, but also prevents the progression of pathology.
Vitamin B12 has the property of accumulating in the human body and being consumed as needed. Strictly speaking, vitamin B12 is a group of substances similar in structure, properties and functions, although most often only cyanocobalamin is understood by this name. When, for one reason or another, the body begins to experience a shortage of this substance, vitamin B12 in ampoules comes to the rescue - the most rational form of its release, which involves introducing the substance into the body by injection.
The biological role of vitamin B12 is the regulation of cellular respiration and vascular tone, participation in the synthesis nucleic acids, maturation of male germ cells, hematopoiesis. Vitamin deficiency can lead to severe anemia, infertility, memory impairment, dizziness, critical loss of muscle mass, increased risk of myocardial infarction and strokes, ulcerative lesions gastrointestinal tract.
As you can see, doctors may have a lot of reasons to prescribe cyanocobalamin in injection ampoules, and you shouldn’t be afraid of this.
The first symptoms of a lack of vitamin B12 in the body are tingling and itching in the fingertips. Almost every vegetarian encounters these sensations when starting their meat-free diet.
Vitamin B12 preparations are currently available in three dosage forms:
The last two forms, of course, are more convenient for the patient to take, since they do not require painful injections for administration. However, injection of the vitamin is the most effective, as it allows you to achieve a therapeutic effect in a shorter time.
In addition, oral administration of vitamin B12 in the form of tablets is ineffective in cases of damage to the ileum with impaired production of Castle factor, which promotes the absorption of cyanocobalamin in the intestine. At helminthic infestations the bioavailability of oral forms of the vitamin is also reduced.
Vitamin B12 solutions for injection are used to treat lesions of the nervous system of various natures, with serious surgical operations on the gastrointestinal tract, severe intoxication, hematopoietic disorders.
Sometimes it is necessary to administer vitamin B12 solutions to people following a strict vegetarian diet, since natural vitamin found mainly in products of animal origin.
Cyanocobalamin - aqueous solution vitamin B12 with sodium chloride. Produced by various manufacturers in ampoules containing 0.2 and 0.5 mg of vitamin B12 each.
The solution is administered intramuscularly, intravenously, subcutaneously or intralumbarally. The price of this drug is 30 rubles for 10 ampoules.
According to the instructions for the use of vitamin B12 in Cyanocobalamin ampoules, from half to three ampoules are administered once at intervals specific to each disease.
For myelosis and sclerosis, the drug is injected into the spinal canal.
This vitamin B12 in ampoules is produced by the German concern Merck. Contraindications include pregnancy, breast-feeding, age under 12 years, allergic reactions to the components of the drug.
Neurobion is a combination of vitamins B1, B6 and B12. Indications for use are neuralgia and neuritis various localizations. Available in the form of an injection solution of 3 ml in an ampoule. The price of a package containing 3 ampoules is about 200 rubles.
“We were prescribed Trigamma, but it was being re-certified. The pharmacy said that there is an analogue, Neurobion, but it is painful to inject. We bought it for lack of an alternative, and now we are suffering.”
Neurorubin is a vitamin B12 preparation in ampoules (and also available in tablet form), an analogue of Neurobion, produced by the German company Mepha. Intended for use for symptoms of vitamin deficiency of vitamins B12, B6 and B1, for anemia and some forms of sclerosis.
For a single administration, the contents of 1-3 ampoules are used, but specific doses should only be prescribed by a doctor!
Vitagamma - vitamin B 12 in Russian-made ampoules, produced by V. Bryntsalov’s company.
In addition to vitamins B1, B6 and B12, it also contains lidocaine, which reduces pain during injection. The price of this drug is approximately 15 rubles for 1 ampoule or 60 rubles for a pack of 5 ampoules.
Trigamma is an analogue of Vitagamma from MosKhimPharmPreparatov.
Also, along with vitamins B1, B6, B12, it contains Lidocaine to reduce painful sensations upon introduction. The drug is contraindicated in children, pregnant and lactating women, people with heart failure and those who have increased sensitivity to vitamin B12 injections.
Beplex is a multivitamin preparation sold in boxes of 10 ampoules of 2 ml each.
Beplex contains vitamins B12, B1, B6, B5 and PP, and is intended for use for symptoms of hypovitaminosis of B vitamins, infectious diseases, digestive tract disorders, neuralgia, encephalopathy and dermatitis.
“We were examined. Diagnosis: anemia at the initial stage, abnormal blood count, leukemia. Beplex was prescribed for treatment and Hematogen as a preventive measure. Vitamin B12 was forbidden to take in tablets, they said that it was poorly absorbed. And it’s good: after a month of treatment, the condition became significantly better.”
Compligam B - another one Russian drug vitamin B12 in ampoules.
Its price is approximately 150 rubles for 10 ampoules of 2 ml. Contains vitamins B12, B1 and B6, as well as lidocaine as a local anesthetic.
The drug Combilipen is an analogue of Compligam B, and contains the same components. The price for Combilipen in ampoules is about 600 rubles for 10 ampoules of 2 ml each.
Prescribed for trigeminal neuralgia, polyneuropathies of various etiologies, inflammation facial nerve and for pain in many diseases of the spine.
Instructions for use: the drug should be administered intramuscularly, 2 ml per day for a week. After 7-10 days, you need to switch to injections with a frequency of 2-3 times a week; for mild forms of the disease, injections with this frequency can be given immediately.
Of all the vitamin B12 preparations in ampoules, you should prefer those that contain lidocaine - these products do not have such painful injections (you need to be sure that you are not allergic to lidocaine). Otherwise, all drugs differ little from each other and have similar effects.
It is important to remember that in any case, only a doctor should prescribe specific vitamin B12 injections! He will choose the drug that is best suited for a particular clinical case, and the one that will be optimal in price. Self-medication in in this case unacceptable.
Injectable vitamin B12 preparations are usually administered intramuscularly. Before injecting vitamin B12, you must wash your hands thoroughly with soap. Wipe the injection site with a cotton ball moistened with alcohol or an alcohol-containing preparation.
Most modern manufacturers produce drugs in ampoules, to open which you just need to click on the mark printed in the form of a dot at the top of the ampoule. To protect your fingers from possible injury from sharp edges or glass fragments, the top of the ampoule should be wrapped in a napkin or cotton wool. If there is no mark, you need to run the nail file or ceramic plate supplied with the drug along the neck of the ampoule several times.
The ampoule is opened by moving away from you. Opened vitamin ampoules cannot be stored.
The quantity and dosage of vitamin B12 in ampoules should be selected in strict accordance with the instructions, and only a doctor should do this. This is especially true when it is necessary to inject vitamins B6 and B12 at the same time - if prescribed incorrectly, such drugs can cause side effects.
Injectable forms of vitamin B12 are usually available as combination drugs, also containing vitamins B1 and B6. The combined administration of these vitamins significantly increases the effectiveness of each of them compared to use separately.
The therapeutic effect of a combination of B vitamins is associated with the acceleration of metabolism in nerve tissues, which contributes to its rapid recovery. That is why the combination of vitamins B1, B6 and B12 in one preparation, in the absence of contraindications, is more preferable than the presence of only B12.
They prescribed us vitamin B12 drops for injections. It’s very inconvenient for me to travel regularly for procedures, so our veterinarian injected me. The instructions for this vitamin in ampoules are simple, so it worked. We bought a product with vitamins B6, B1 and B12, the doctor said that it was better than taking only B12.”
Galina Pavlovna, Eremeyskoye
It is possible (and often even necessary) to inject vitamins B12 and B6 at the same time, but only after agreement with your doctor.
It should be remembered that vitamins are substances with exceptionally high biological activity that perform fine regulation of various body functions and can not only improve the patient’s condition, but also cause significant harm to health if used incorrectly. Therefore, the decision on the need to use vitamin preparations for injections, timing and dosage regimen should only be taken by a doctor.
International name. Pyridoxine.
Composition and release form. Solution for injection, 1 ampoule with 1 ml of solution for injection contains 0.05 g, 0.1 g or 0.15 g of pyridoxine hydrochloride, 10 pcs in a cardboard box.
Pharmacological action. Vitamin B6 (pyridoxine) regulates protein metabolism. This is due to its participation in the transport of amino acids through cell membranes. Pyridoxine increases the content of creatinine in striated muscles, which plays an important role in the process of muscle contraction. Takes part in fat and lipid metabolism, improves the absorption of unsaturated fatty acids. With a deficiency of vitamin B6 (pyridoxine), the activity of glucose-6-phosphate dehydrogenase, one of the enzymes for the direct oxidation of glucose in the pentose-phosphate cycle, decreases. Pyridoxal-5-phosphate is part of phosphorylase, which regulates the breakdown of glycogen. Significantly affects hematopoiesis and immunity. Vitamin B6 (pyridoxine) synthesizes erythropoiesis, leukopoiesis and hemoglobin biosynthesis; activates cellular factors of nonspecific immunological reactivity of the body. Helps stabilize blood sugar, encourages cells to metabolize blood glucose and resists eye damage and vision loss due to diabetic retinopathy. Regular use of vitamin B6 reduces the level of xanthurenic acid, a dangerous chemical by-product of vitamin B6 deficiency that can cause diabetes. It can remove from the body the risk factor for heart disease - homocysteine - an amino acid, the increased content of which in the blood leads to strokes and myocardial infarctions. In the absence of vitamin B6, the blood becomes thicker and more prone to form clots that clog arteries. In addition, pyridoxine acts as a diuretic, helping to reduce water retention in the body and, as a result, reduce blood pressure. Pyridoxine improves an indicator of the functioning of our immune system - the number of T cells. Plays a central role in maintaining balance female hormones. By helping convert estradiol, a type of estrogen, into estriol, its least harmful and least carcinogenic form, vitamin B6 counteracts one of the causes of cancer in women. He must be integral part treatment programs for uterine fibroids, endometriosis or fibrocystic mastopathy. Being natural diuretic, pyridoxine brings welcome relief from premenstrual tension. In combination with magnesium orthophosphate, vitamin B6 (pyridoxine) minimizes the formation of calcium oxalate, the main component of most kidney stones. Promotes the production of norepinephrine and serotonin - neurochemicals responsible for a sense of well-being and good mood.
Indications for taking vitamin B6. Hypo- and vitamin deficiency B6 (treatment and prevention) - malnutrition, long-term infections, diarrhea, enteritis, sprue, prolonged stress, malabsorption syndrome, condition after removal of the stomach and large sections of the intestine, hemodialysis. As part of complex therapy: hypochromic and microcytic anemia, parkinsonism, radiculitis, Little's disease, Meniere's disease and syndrome, neuritis (including against the background of diabetes mellitus), neuralgia, congenital pyridoxine-dependent convulsive syndrome in newborns, prevention of seizures in patients with time of taking ftivazid; gestosis, alcoholism, liver damage caused by ethanol and anti-tuberculosis drugs, acute and chronic hepatitis, to increase diuresis and enhance the effect of diuretics. Dermatitis (including atopic and seborrheic), herpetic infections(Varicella zoster, Herpes simplex), psoriasis, exudative diathesis.
Contraindications for the use of vitamin B6. Hypersensitivity. Caution. Peptic ulcer of the stomach and duodenum, coronary heart disease.
Side effects. Allergic reactions, hypersecretion of HCl, numbness, a feeling of constriction in the limbs - a symptom of “stockings” and “gloves”, decreased lactation (sometimes this is used as a therapeutic effect); rarely - convulsions (occur only with rapid administration).
Dosage regimen. For the treatment of sideroblastic anemia, 100 mg is prescribed intramuscularly, 2 times a week. It is advisable to simultaneously take folic acid, cyanocobalamin, and riboflavin. For parkinsonism - intramuscularly, 100 mg/day; for a course of injections, the course of treatment is repeated after 2-3 months or, starting with a dose of 1 mg/day, the dose is increased daily by 50 mg, bringing it to 1 mg/day, in the form of a single injection over the course of a day. For depression of involutional age - intramuscularly, 200 mg/day.
For the treatment of pyridoxine-dependent convulsive syndrome in adults - intravenously or intramuscularly, mg; childrenmg daily.
Interaction with other drugs. Strengthens the effect of diuretics; weakens the activity of levodopa. Isonicotine hydrazide, penicillamine, cycloserine and estrogen-containing oral contraceptives weaken the effect of pyridoxine. Combines well with cardiac glycosides (pyridoxine helps increase the synthesis of contractile proteins in the myocardium), with glutamic acid and asparkam (increases resistance to hypoxia). Pharmaceutically incompatible with vitamins B1 and B12, in powder with ascorbic and nicotinic acids.
Storage conditions. Vitamin B6 (pyridoxine) should be stored in a dry, cool place, out of reach of children, at a temperature not exceeding +25°C.
Manufacturer. WEIMER PHARMA, Germany.
Use of the drug vitamin B6 only as prescribed by a doctor, instructions are given for reference!
According to scientists, which is based on their numerous studies, modern man does not receive the norm he needs useful substances(vitamins, minerals). We usually get these substances from food. But few modern people follow the principles of healthy, balanced nutrition, preferring snacks, semi-finished products and mono-diets. Hence the emergence of a deficiency of vitamins, minerals, and other essential substances.
Very often the body lacks vitamin B6. This is one of the vital important elements essential for health. Its daily requirement is 2.0 mg per day and no less. Vitamin B6 is involved in the synthesis of serotonin, known as the hormone of happiness. Therefore, it is often called an antidepressant vitamin. Subject to availability required quantity B6 in the blood, a person does not lose peace of mind, he often experiences joyful emotions, being in a good psycho-emotional state.
With its deficiency, a person suffers from insomnia, dermatitis develops on the skin, and attacks of irritability occur more and more often. Also, a deficiency of this substance has negative influence to the liver.
Any modern pharmacy offers vitamin ampoules with vitamin B6 or tablets. Each package contains instructions for this drug. But you can take additional vitamin B6 only as prescribed by a doctor, after appropriate medical examination. Remember that an excess of it is no less dangerous than a deficiency. But treating the consequences of such an excess is much more difficult.
What are the indications for use of the vitamin B6 drug?
First of all, the drug is prescribed in the presence of hypo- and vitamin deficiency of this particular substance. This often happens with various diets, poor nutrition. The remedy is also indicated in the treatment of long-term infectious diseases.
The drug is effective for diarrhea, enteritis, malabsorption syndrome. It is prescribed for stressful conditions, as well as the condition after resection of the stomach and intestines. Recommended during hemodialysis.
The vitamin is prescribed as part of complex therapy for hypochromic or microcytic anemia. Included in the treatment of Parkinson's disease, radiculitis, Little's disease, neuritis and neuralgia.
Used in the treatment of congenital pyridoxine-dependent convulsive syndrome, sometimes observed in newborns. Prescribed as a means of preventing convulsive conditions in patients while taking ftivazid.
Prescribed for complex therapy of gestosis and alcoholism. For liver pathologies that appeared due to the use of ethanol or anti-tuberculosis drugs. It is often recommended to be taken by patients with hepatitis in order to enhance diuresis and enhance the effect of diuretic drugs.
Vitamin B6 is often prescribed to heart patients to regulate blood pressure. It is recommended to take during treatment depressive states.
Often, preparations with this vitamin are prescribed for skin diseases- lichen dermatitis, with frequent exacerbations of herpes and psoriasis. Prescribed for neurodermatitis, in the treatment of seborrhea, exudative diathesis.
Prescribed for the treatment of autism and epilepsy. The drug is indicated for patients with generalized anxiety.
What is the dosage and use of vitamin B6?
Pills:
The drug in tablets is taken after meals. WITH for preventive purposes take 0.002-0.005 g per day for adults.
What is the use of vitamin B6 in solution for injection?
The vitamin is administered intramuscularly:
For the treatment of sideroblastic anemia - 100 mg twice a week. At the same time, folic acid, cyanocobalamin and riboflavin are usually prescribed.
For the treatment of parkinsonism - 100 mg per day. The course is 20-25 injections. If necessary, treatment is repeated after 2-3 months.
In the treatment of depressive states of involutional age - 200 mg per day with intramuscular administration.
When treating convulsive syndrome (pyridoxine-dependent):
Adults: IV or IM - 30-600 mg per day.
Children: 10-100 mg per day.
What are the contraindications for vitamin B6?
Additional doses or treatment with B6 should not be prescribed to patients with hypersensitivity. For strict restrictions of the drug, vitamin B6, the instructions for use refer to patients with peptic ulcer disease, as well as those suffering from cardiac ischemia.
What are the side effects of vitamin B6?
When using drugs that are sources of this substance, allergic manifestations are possible, such as skin rashes, swelling, redness of the skin, itching. Hypersecretion of HCl may occur. Sometimes the patient complains of a feeling of squeezing in the arms and legs. Lactating women experience a decrease in lactation. With rapid administration of the drug, convulsions may occur.
You will learn even more detailed information about the properties and use of vitamin B6 from the original paper instructions, which you will find in the package with the drug.
Do not self-prescribe medications. Do not risk your own health, always seek a prescription from a doctor. Be healthy!
This B vitamin is important for human metabolism. B6 contributes to the proper functioning of the nervous system. In pharmacology it is accepted international name active substance– pyridoxine. In the human body it acts as a coenzyme and promotes the normal absorption of amino acids. Participates in the production of the “transport mechanism” of human blood - hemoglobin. It can have a positive effect on glucose levels, stabilizing them and protecting a person from their fluctuations.
Pyridoxine hydrochloride solution for injection, as well as tablets and capsules. Trade names– pyridoxine, pyridoxal, vitamin B6.
The vitamin is absorbed from food and is involved in protein synthesis. This is its main purpose. Also involved in lipid metabolism. There is evidence that adequate dosages of B6 can prevent the so-called “ cholesterol disease“—increased levels of “bad” cholesterol. The vitamin is often prescribed to such patients.
It promotes the synthesis of hemoglobin, thereby participating in the formation of red blood cells. A lack of vitamin B6 can manifest itself in a decrease in hemoglobin levels too.
Affects the state of the nervous system, promotes the adequacy of reactions of excitation and inhibition. According to some data, it can accelerate the process of recovery of the nervous system after it is “accelerated” by stimulants.
Participates in the process of glucose uptake by brain cells. Helps to “even out” blood sugar levels and is indicated for sudden fluctuations. Increases mental performance by improving nutrition of brain cells.
It has a lipotropic effect, promotes the normal functioning of the human liver, and also participates in fat metabolism. However, in this regard, it is a mistake to believe that the vitamin is a fat burner. It is not capable of catalyzing the processes of utilization of fatty deposits, but its deficiency can also result in impaired liver function.
It enters the human body with food and supplements, but can also be synthesized by healthy intestinal flora.
Indications for the use of pyridoxine are symptoms of its deficiency. They can be systemic and are quite easily confused with manifestations of various diseases. Therefore, vitamins must be prescribed by a doctor after a series of tests.
Vitamin B6 deficiency can manifest itself:
Other symptoms include cracks in the corners of the lips, tingling sensations in the fingers, numbness in the limbs and hair loss. This part of the manifestations may be mixed with the usual symptoms of malnutrition.
Some experts associate B6 deficiency with poor circulation, as well as with the state when without visible reasons a person feels chronic fatigue and cannot get rid of it.
In sports, the very nature of the athlete’s activities is often considered an indication. In particular, those training for muscle hypertrophy using bodybuilding methods experience a vitamin deficiency due to the fact that they consume increased amounts of protein foods. In sports practice, the dosage is increased to the maximum, 100 mg, but it cannot be increased further, as this can lead to poisoning and hypervitaminosis.
Vitamin B6 is also used when withdrawing from various stimulants. It can help relieve withdrawal symptoms. In practice recent years its injectable forms are administered when withdrawal syndrome occurs after using fat burners that stimulate the nervous system. Withdrawal syndrome in this case manifests itself in the form of depression and decreased tone.
The need for vitamins also increases when taken birth control pills, fever, cold. In addition, in individuals who abuse nicotine and alcohol, the need for this vitamin can be significantly increased.
The causes of vitamin B6 deficiency are usually described as poor-quality nutrition with a predominance of unnatural foods and fast food, as well as overwork and physical overload with inadequate support with vitamin preparations and against the background of poor-quality nutrition.
Vitamin B6 is found in many food products, and among them there are both plant and animal, and quite a lot of sources of complete protein. Most of it is found in spinach, carrots, white and cauliflower, mackerel, cherries, lemons and oranges. Some amounts can also be obtained from dairy products, including cheese and cottage cheese. Also found in poultry meat, some types of fish and eggs. Some amount can be obtained with buckwheat and potatoes.
Use with caution for coronary heart disease and duodenal ulcers. May be toxic in severe liver damage. Also used carefully when various diseases Gastrointestinal tract. Typically, “caution” means that vitamins are administered by injection rather than in the form of tablets and capsules.
An overdose is detected when the substance accumulates in tissues. This is possible with long-term use in high doses. Treatment of overdose is symptomatic, usually manifested in drug withdrawal rather than exclusion. food sources vitamin B6.
Symptoms of overdose may include skin rashes in the early stages and seizures later, but they do not appear in all cases.
Different sources indicate different dosages. In foreign countries – 2 mg for an adult healthy person and 2.5 mg for pregnant women. In domestic ones - 1.5 mg for adults, 2-2.5 mg for pregnant women and from 0.3 mg for children of the first year of life.
The need for taking the vitamin increases in people with tuberculosis; in this case, the dosage is increased individually, depending on the main drugs used to treat the disease.
The effectiveness of vitamin preparations decreases against the background contraception, as well as human estrogen preparations taken for HRT. Taking penicillamine and cuprimin helps bind vitamin B6 and remove it from the body. Vitamin B6 also interacts with corticosteroids; they can contribute to its elimination and the occurrence of deficiency.
Pyridoxine is less easily absorbed in alcoholics, as well as in people who constantly take alcohol-containing medical supplies. May affect the absorption and effect of anti-TB drugs. Often reduces the effectiveness of drugs against Parkinson's disease.
Especially for – fitness trainer Elena Selivanova
Vitamin B 6 is a group of substances consisting of three interchangeable isomers with equal activity: pyridoxole, pyridoxal, pyridoxamine. All three names are suitable to refer to the vitamin. But to avoid confusion, in chemistry and pharmaceuticals it is customary to use one name for isomers - pyridoxine. Sometimes in the scientific literature you can find the old names of the substance - adermin and factor Y. Pyridoxine is available in tablets and in injection solutions of any kind. In most cases, tableted vitamins are used to prevent hypovitaminosis and normalize the condition of hair, skin, and nail plates.
For the tablet form of release it is used active ingredient in the form of pyridoxine hydrochloride. In one tablet of the drug different manufacturers contains 2, 5 or 10 mg of active substance.
In the pharmacy, tablet vitamins can be found under two names:
Vitamin B6 is also the main component of brewer's yeast, sold as a dietary supplement. Brewer's yeast is purchased primarily by women. The dietary supplement brings great benefits to the female body, significantly improves the condition of the skin, strengthens hair and nails.
In addition to single-component preparations and dietary supplements, multicomponent preparations based on group B compounds can be used as sources of vitamin B6. There are much more multivitamin preparations sold in the pharmacy chain than single-component sources of pyridoxine. Among the most effective and popular vitamin complexes can be noted:
Pyridoxine is involved in metabolic reactions and is needed for the proper functioning of all parts of the nervous system. The basis of the pharmacological action of the substance is its participation in the metabolism of the hormone histamine and many amino acids. The vitamin ensures normal lipid metabolism.
In the body, pyridoxine undergoes phosphorylation and is converted into pyridoxal-5-phosphate. In this form, it is included in the enzymes that break down amino acids.
Usually the vitamin enters the body in sufficient quantities. Pyridoxine deficiency is a rare phenomenon, diagnosed mainly in young children fed artificial formula. Hypovitaminosis B6 in infants is manifested by anemia, convulsive conditions, stool disorders, and sometimes peripheral neuropathy.
Taking pyridoxine is indicated for a variety of pathological conditions:
Tablet preparations based on vitamin B 6 are taken orally. Reception is carried out after meals.
The preventive dose for hypovitaminosis is 2–5 mg per day for adults, and no more than 2 mg for children. The therapeutic dose, according to the instructions for use, is 20–30 mg 1 or 2 times a day for an adult patient. For children with therapeutic purpose the drug is prescribed in different doses depending on the age of the child.
The course of treatment lasts 1 – 2 months.
Some buyers are interested in the question of whether it is possible to use not tableted pyridoxine for oral administration, but a solution of the vitamin in ampoules. Drinking the vitamin in this form is harmless, but also useless. The substance from the ampoule solution is absorbed into digestive tract only by 10%. Therefore, if taking pills is contraindicated, it is better to give vitamin injections into a muscle or vein.
The only absolute contraindications are intolerance to the components. Caution is required when taking vitamins when peptic ulcer and ischemia.
From side effects problems that occur when taking the drug in large quantities are most often observed:
Pyridoxine increases the effect of diuretic drugs, but reduces the effect of antiparkinsonian drugs.
The effectiveness of the vitamin is reduced when taken simultaneously with antituberculosis drugs isonicotinic acid hydrazide and estrogen-based contraceptives.
Pyridoxine has good compatibility with cardiac glycosides (the vitamin helps synthesize protein structures that ensure contraction of the heart muscle) and glutamic acid preparations.
Do not take pyridoxine, thiamine and cobalamin together. In powder form, vitamin B 6 is incompatible with vitamin C and niacin.
Pyridoxine preparations are stored in a shaded place out of reach of children.
Vitamin tablets are suitable for use for 3 years.
Vitamin B 6 tablets are inexpensive. The price of a package containing 50 tablets (10 mg each) ranges from 30 to 70 rubles in different pharmacies.
